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Aliases for MIR5197 Gene

Subcategory (RNA class) for MIR5197 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5197 Gene

  • MicroRNA 5197 2 3 5
  • Hsa-Mir-5197 3

External Ids for MIR5197 Gene

Previous GeneCards Identifiers for MIR5197 Gene

  • GC05U901590
  • GC05P143062

Summaries for MIR5197 Gene

Entrez Gene Summary for MIR5197 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5197 Gene

MIR5197 (MicroRNA 5197) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5197 Gene

Genomics for MIR5197 Gene

Regulatory Elements for MIR5197 Gene

Enhancers for MIR5197 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05F143680 1.1 Ensembl ENCODE 0.8 +2.5 2527 3.1 THRB RAD21 RARA ZNF366 FOS CREM MIXL1 THAP11 HMG20B ZNF362 NR3C1 MIR5197 LOC100420513
GH05F143693 1.4 FANTOM5 Ensembl ENCODE 0.4 +14.4 14358 1.8 HDGF PKNOX1 MLX ARID4B BMI1 RAD21 ZBTB40 RARA MIER2 TBX21 KCTD16 MIR5197 LOC100420513
GH05F143674 0.8 ENCODE 0.4 -5.7 -5710 0.2 ELF3 MLX RAD21 ZBTB40 RARA CREM MIXL1 HMG20B TGIF2 CEBPA MIR5197 GC05M143652
GH05F143657 0.7 Ensembl 0.3 -21.9 -21859 0.4 GATAD2A NFIA YY2 FOXA3 CEBPB FEZF1 ZEB2 ZIC2 OSR2 JUND GC05M143652 MIR5197
GH05F143698 0.6 FANTOM5 0.3 +18.8 18840 0.2 KLF1 NFE2 ZSCAN29 EP300 RFX5 MIR5197 LOC100420513
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5197 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5197 Gene

Chromosome:
5
Start:
143,679,860 bp from pter
End:
143,679,971 bp from pter
Size:
112 bases
Orientation:
Plus strand

Genomic View for MIR5197 Gene

Genes around MIR5197 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5197 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5197 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5197 Gene

Proteins for MIR5197 Gene

Post-translational modifications for MIR5197 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5197 Gene

Domains & Families for MIR5197 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5197 Gene

Function for MIR5197 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5197 Gene

Localization for MIR5197 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5197 Gene

Pathways & Interactions for MIR5197 Gene

SuperPathways for MIR5197 Gene

No Data Available

Interacting Proteins for MIR5197 Gene

Gene Ontology (GO) - Biological Process for MIR5197 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5197 Gene

Transcripts for MIR5197 Gene

mRNA/cDNA for MIR5197 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5197 Gene

No ASD Table

Relevant External Links for MIR5197 Gene

GeneLoc Exon Structure for
MIR5197
ECgene alternative splicing isoforms for
MIR5197

Expression for MIR5197 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5197 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5197 Gene:

MIR5197
genes like me logo Genes that share expression patterns with MIR5197: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5197 Gene

Orthologs for MIR5197 Gene

Evolution for MIR5197 Gene

ENSEMBL:
Gene Tree for MIR5197 (if available)
TreeFam:
Gene Tree for MIR5197 (if available)

No data available for Orthologs for MIR5197 Gene

Paralogs for MIR5197 Gene

No data available for Paralogs for MIR5197 Gene

Variants for MIR5197 Gene

Sequence variations from dbSNP and Humsavar for MIR5197 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs10051292 -- 143,678,512(+) TCCCA(A/T)CTTTA upstream-variant-2KB
rs10051301 -- 143,678,548(+) TTTTC(A/C)TACTT upstream-variant-2KB
rs111891198 -- 143,680,394(+) TCTCT(C/T)TTTTT downstream-variant-500B
rs112632817 -- 143,680,395(+) TCTTT(C/T)TTTTT downstream-variant-500B
rs11348891 -- 143,680,392(+) CTCTC(-/T)TTTTT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR5197 Gene

Variant ID Type Subtype PubMed ID
nsv830512 CNV gain 17160897

Relevant External Links for MIR5197 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5197

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5197 Gene

Disorders for MIR5197 Gene

Relevant External Links for MIR5197

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5197

No disorders were found for MIR5197 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5197 Gene

Publications for MIR5197 Gene

  1. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5197 Gene

Sources for MIR5197 Gene

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