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Aliases for MIR5196 Gene

Subcategory (RNA class) for MIR5196 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5196 Gene

  • MicroRNA 5196 2 3 5
  • Hsa-Mir-5196 3
  • Mir-5196 3

External Ids for MIR5196 Gene

Previous GeneCards Identifiers for MIR5196 Gene

  • GC19U901559
  • GC19P035840
  • GC19P035848
  • GC19P035959
  • GC19P035502
  • GC19P035511
  • GC19P035520
  • GC19P035323
  • GC19P036109
  • GC19P036225

Summaries for MIR5196 Gene

Entrez Gene Summary for MIR5196 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5196 Gene

MIR5196 (MicroRNA 5196) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Class I MHC mediated antigen processing and presentation and Antigen activates B Cell Receptor (BCR) leading to generation of second messengers.

Additional gene information for MIR5196 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5196 Gene

Genomics for MIR5196 Gene

Regulatory Elements for MIR5196 Gene

Enhancers for MIR5196 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H035345 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.7 +2.1 2139 4 HDGF ZNF766 ZNF143 ZNF207 ATF7 RUNX3 CAVIN1 JUNB ZNF592 NBN FFAR1 FFAR2 FFAR3 CD22 U2AF1L4 GRAMD1A USF2 FXYD5 IGFLR1 MIR5196
GH19H035339 0.6 dbSUPER 0.7 -4.1 -4094 4 POLR2A ZNF366 ETV6 ZNF300 ZNF433 ZKSCAN1 ZNF599 TMEM147-AS1 HAUS5 MAG ENSG00000271049 CD22 ETV2 FFAR1 U2AF1L4 MIR5196
GH19H035337 0.6 dbSUPER 0.4 -7.8 -7761 1 HDGF ZNF362 POLR2A IKZF1 PRDM10 SPI1 MAG KRTDAP DMKN HAMP ENSG00000233214 FAM187B TMEM147 TMEM147-AS1 ENSG00000232680 FXYD3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5196 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5196 Gene

Chromosome:
19
Start:
35,345,513 bp from pter
End:
35,345,627 bp from pter
Size:
115 bases
Orientation:
Plus strand

Genomic View for MIR5196 Gene

Genes around MIR5196 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5196 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5196 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5196 Gene

Proteins for MIR5196 Gene

Post-translational modifications for MIR5196 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5196 Gene

Domains & Families for MIR5196 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5196 Gene

Function for MIR5196 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5196
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5196 Gene

Localization for MIR5196 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5196 Gene

Drugs & Compounds for MIR5196 Gene

No Compound Related Data Available

Transcripts for MIR5196 Gene

mRNA/cDNA for MIR5196 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5196
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5196 Gene

No ASD Table

Relevant External Links for MIR5196 Gene

GeneLoc Exon Structure for
MIR5196
ECgene alternative splicing isoforms for
MIR5196

Expression for MIR5196 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5196 Gene

mRNA differential expression in normal tissues according to GTEx for MIR5196 Gene

This gene is overexpressed in Spleen (x9.4) and Ovary (x6.7).

NURSA nuclear receptor signaling pathways regulating expression of MIR5196 Gene:

MIR5196
genes like me logo Genes that share expression patterns with MIR5196: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5196 Gene

Orthologs for MIR5196 Gene

Evolution for MIR5196 Gene

ENSEMBL:
Gene Tree for MIR5196 (if available)
TreeFam:
Gene Tree for MIR5196 (if available)

No data available for Orthologs for MIR5196 Gene

Paralogs for MIR5196 Gene

No data available for Paralogs for MIR5196 Gene

Variants for MIR5196 Gene

Sequence variations from dbSNP and Humsavar for MIR5196 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000176298 -- 35,345,822(+) GGCAC(C/G/T)CTGAT intron-variant, downstream-variant-500B
rs1000988588 -- 35,344,062(+) GTGGT(A/G)GCGCG intron-variant, upstream-variant-2KB
rs1001197427 -- 35,343,715(+) TCATA(A/G)CAGGA intron-variant, upstream-variant-2KB
rs1001738617 -- 35,343,742(+) AATAC(A/C)AAAAA intron-variant, upstream-variant-2KB
rs1010286663 -- 35,343,565(+) GTTCT(A/G)TATCT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5196 Gene

Variant ID Type Subtype PubMed ID
esv2758758 CNV loss 17122850
nsv1067129 CNV loss 25217958
nsv510765 CNV deletion 20534489
nsv833810 CNV gain 17160897

Relevant External Links for MIR5196 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5196

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5196 Gene

Disorders for MIR5196 Gene

Relevant External Links for MIR5196

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5196

No disorders were found for MIR5196 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5196 Gene

Publications for MIR5196 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5196 Gene

Sources for MIR5196 Gene

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