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Aliases for MIR5194 Gene

Subcategory (RNA class) for MIR5194 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5194 Gene

  • MicroRNA 5194 2 3 5
  • Hsa-Mir-5194 3
  • Mir-5194 3

External Ids for MIR5194 Gene

Previous GeneCards Identifiers for MIR5194 Gene

  • GC08U901596
  • GC08M131023

Summaries for MIR5194 Gene

Entrez Gene Summary for MIR5194 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5194 Gene

MIR5194 (MicroRNA 5194) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5194 Gene

Genomics for MIR5194 Gene

Regulatory Elements for MIR5194 Gene

Enhancers for MIR5194 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F130007 1.1 Ensembl ENCODE 0.8 -0.1 -67 2.2 PKNOX1 TBL1XR1 WRNIP1 BMI1 YY1 RELA POLR2A EGR1 CBX5 EED MIR5194 FAM49B
GH08F130012 1.1 ENCODE 0.4 -6.7 -6709 5.2 HDGF ATF1 PKNOX1 ARNT SIN3A ZNF2 ZNF121 GTF3C2 GLIS2 CBX5 ASAP1 FAM49B MIR5194
GH08F130005 0.4 ENCODE 0.8 +3.0 3024 0.8 ZMYM3 RNU7-181P MIR5194
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5194 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5194 Gene

Chromosome:
8
Start:
130,008,334 bp from pter
End:
130,008,453 bp from pter
Size:
120 bases
Orientation:
Minus strand

Genomic View for MIR5194 Gene

Genes around MIR5194 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5194 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5194 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5194 Gene

Proteins for MIR5194 Gene

Post-translational modifications for MIR5194 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5194 Gene

Domains & Families for MIR5194 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5194 Gene

Function for MIR5194 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5194 Gene

Localization for MIR5194 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5194 Gene

Pathways & Interactions for MIR5194 Gene

SuperPathways for MIR5194 Gene

No Data Available

Interacting Proteins for MIR5194 Gene

Gene Ontology (GO) - Biological Process for MIR5194 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5194 Gene

Transcripts for MIR5194 Gene

mRNA/cDNA for MIR5194 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5194 Gene

No ASD Table

Relevant External Links for MIR5194 Gene

GeneLoc Exon Structure for
MIR5194
ECgene alternative splicing isoforms for
MIR5194

Expression for MIR5194 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5194 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5194 Gene:

MIR5194
genes like me logo Genes that share expression patterns with MIR5194: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5194 Gene

Orthologs for MIR5194 Gene

Evolution for MIR5194 Gene

ENSEMBL:
Gene Tree for MIR5194 (if available)
TreeFam:
Gene Tree for MIR5194 (if available)

No data available for Orthologs for MIR5194 Gene

Paralogs for MIR5194 Gene

No data available for Paralogs for MIR5194 Gene

Variants for MIR5194 Gene

Sequence variations from dbSNP and Humsavar for MIR5194 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs111396287 -- 130,008,895(+) GTTTT(C/G)AGCAA intron-variant, upstream-variant-2KB
rs113080038 -- 130,009,269(+) GCATC(-/T)TTTTT intron-variant, upstream-variant-2KB
rs114858933 -- 130,008,965(+) ACTGA(C/G)GCTCT intron-variant, upstream-variant-2KB
rs114897220 -- 130,008,935(+) GTCTA(C/T)ATGTT intron-variant, upstream-variant-2KB
rs116564594 -- 130,008,006(+) GTGTT(C/T)AAGAC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR5194 Gene

Variant ID Type Subtype PubMed ID
nsv612233 CNV loss 21841781
nsv612232 CNV loss 21841781
nsv612231 CNV gain 21841781
nsv524349 CNV gain 19592680
nsv465808 CNV loss 19166990
nsv1161802 CNV deletion 26073780
nsv1018045 CNV gain 25217958
esv3576608 CNV gain 25503493

Relevant External Links for MIR5194 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5194

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5194 Gene

Disorders for MIR5194 Gene

Relevant External Links for MIR5194

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5194

No disorders were found for MIR5194 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5194 Gene

Publications for MIR5194 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5194 Gene

Sources for MIR5194 Gene

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