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Aliases for MIR5193 Gene

Subcategory (RNA class) for MIR5193 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5193 Gene

  • MicroRNA 5193 2 3 5
  • Hsa-Mir-5193 3
  • Mir-5193 3

External Ids for MIR5193 Gene

Previous GeneCards Identifiers for MIR5193 Gene

  • GC03U901841
  • GC03M049847
  • GC03M049849

Summaries for MIR5193 Gene

Entrez Gene Summary for MIR5193 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5193 Gene

MIR5193 (MicroRNA 5193) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template and Interferon gamma signaling.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5193 Gene

Genomics for MIR5193 Gene

Regulatory Elements for MIR5193 Gene

Enhancers for MIR5193 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G049802 1.3 ENCODE dbSUPER 0.7 +0.5 468 7.2 HDGF FOXA2 MLX WRNIP1 SIN3A ARID4B YBX1 DMAP1 ZNF2 YY1 CDHR4 FAM212A AMT WDR6 MIR5193
GH03G049812 1.1 ENCODE dbSUPER 0.4 -7.7 -7711 2.5 ELF3 FOXA2 ARID4B RAD21 ZBTB40 ZNF766 RELB IKZF2 THAP11 HCFC1 CDHR4 UBA7 MIR5193
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5193 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5193 Gene

Chromosome:
3
Start:
49,806,137 bp from pter
End:
49,806,245 bp from pter
Size:
109 bases
Orientation:
Minus strand

Genomic View for MIR5193 Gene

Genes around MIR5193 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5193 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5193 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5193 Gene

Proteins for MIR5193 Gene

Post-translational modifications for MIR5193 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5193 Gene

Domains & Families for MIR5193 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5193 Gene

Function for MIR5193 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5193 Gene

Localization for MIR5193 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5193 Gene

Pathways & Interactions for MIR5193 Gene

genes like me logo Genes that share pathways with MIR5193: view

Interacting Proteins for MIR5193 Gene

Gene Ontology (GO) - Biological Process for MIR5193 Gene

None

No data available for SIGNOR curated interactions for MIR5193 Gene

Drugs & Compounds for MIR5193 Gene

No Compound Related Data Available

Transcripts for MIR5193 Gene

mRNA/cDNA for MIR5193 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5193 Gene

No ASD Table

Relevant External Links for MIR5193 Gene

GeneLoc Exon Structure for
MIR5193
ECgene alternative splicing isoforms for
MIR5193

Expression for MIR5193 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5193 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5193 Gene:

MIR5193
genes like me logo Genes that share expression patterns with MIR5193: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5193 Gene

Orthologs for MIR5193 Gene

Evolution for MIR5193 Gene

ENSEMBL:
Gene Tree for MIR5193 (if available)
TreeFam:
Gene Tree for MIR5193 (if available)

No data available for Orthologs for MIR5193 Gene

Paralogs for MIR5193 Gene

No data available for Paralogs for MIR5193 Gene

Variants for MIR5193 Gene

Sequence variations from dbSNP and Humsavar for MIR5193 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000827279 -- 49,808,231(+) CTCCT(C/T)TTGAT intron-variant, upstream-variant-2KB
rs1003079643 -- 49,806,381(+) CGCAC(A/G)GGGAA intron-variant, upstream-variant-2KB
rs1003933823 -- 49,806,291(+) GGGGT(-/G)GGGGG intron-variant, upstream-variant-2KB
rs1005032107 -- 49,808,209(+) CTGTC(A/G)GGGGG intron-variant, upstream-variant-2KB
rs1007637878 -- 49,805,817(+) GGCTG(A/G)GAAGA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR5193 Gene

Variant ID Type Subtype PubMed ID
nsv834688 CNV loss 17160897

Relevant External Links for MIR5193 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5193

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5193 Gene

Disorders for MIR5193 Gene

Relevant External Links for MIR5193

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5193

No disorders were found for MIR5193 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5193 Gene

Publications for MIR5193 Gene

  1. Human miR-5193 Triggers Gene Silencing in Multiple Genotypes of Hepatitis B Virus. (PMID: 26456535) Khlaiphuengsin A. … Payungporn S. (Microrna 2015) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5193 Gene

Sources for MIR5193 Gene

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