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Aliases for MIR518D Gene

Subcategory (RNA class) for MIR518D Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR518D Gene

  • MicroRNA 518d 2 3
  • Hsa-Mir-518d 3
  • AC011453.3 5
  • MIRN518D 3

External Ids for MIR518D Gene

Previous HGNC Symbols for MIR518D Gene

  • MIRN518D

Previous GeneCards Identifiers for MIR518D Gene

  • GC19P058971
  • GC19P059015
  • GC19P054239
  • GC19P054241
  • GC19P054274
  • GC19P054324
  • GC19P054344
  • GC19P054415
  • GC19P054497

Summaries for MIR518D Gene

Entrez Gene Summary for MIR518D Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR518D Gene

MIR518D (MicroRNA 518d) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR518D Gene

Genomics for MIR518D Gene

Genomic Location for MIR518D Gene

Chromosome:
19
Start:
53,734,863 bp from pter
End:
53,734,981 bp from pter
Size:
119 bases
Orientation:
Plus strand

Genomic View for MIR518D Gene

Genes around MIR518D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR518D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR518D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR518D Gene

No data available for Regulatory Elements for MIR518D Gene

Proteins for MIR518D Gene

Post-translational modifications for MIR518D Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR518D Gene

Domains & Families for MIR518D Gene

Gene Families for MIR518D Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR518D: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR518D Gene

Function for MIR518D Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR518D Gene

Localization for MIR518D Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR518D Gene

Pathways & Interactions for MIR518D Gene

SuperPathways for MIR518D Gene

No Data Available

Interacting Proteins for MIR518D Gene

Gene Ontology (GO) - Biological Process for MIR518D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR518D Gene

Drugs & Compounds for MIR518D Gene

No Compound Related Data Available

Transcripts for MIR518D Gene

mRNA/cDNA for MIR518D Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR518D Gene

No ASD Table

Relevant External Links for MIR518D Gene

GeneLoc Exon Structure for
MIR518D
ECgene alternative splicing isoforms for
MIR518D

Expression for MIR518D Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR518D Gene

Orthologs for MIR518D Gene

Evolution for MIR518D Gene

ENSEMBL:
Gene Tree for MIR518D (if available)
TreeFam:
Gene Tree for MIR518D (if available)

No data available for Orthologs for MIR518D Gene

Paralogs for MIR518D Gene

No data available for Paralogs for MIR518D Gene

Variants for MIR518D Gene

Sequence variations from dbSNP and Humsavar for MIR518D Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs73053512 -- 53,733,412(+) TCATA(A/T)CACTA upstream-variant-2KB
rs73600979 -- 53,733,322(+) TATGC(C/T)GGGCA upstream-variant-2KB
rs73600982 -- 53,733,447(+) GTGTG(C/G)TTTTT upstream-variant-2KB
rs73600983 -- 53,733,518(+) CGGCT(C/G/T)ACTGT upstream-variant-2KB
rs73600986 -- 53,733,585(+) CACAG(C/T)GGGCT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR518D Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
nsv458781 CNV Gain 19166990
esv2718833 CNV Deletion 23290073
esv2718837 CNV Deletion 23290073
esv2448351 CNV Deletion 19546169

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for MIR518D Gene

Disorders for MIR518D Gene

Relevant External Links for MIR518D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR518D

No disorders were found for MIR518D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR518D Gene

Publications for MIR518D Gene

  1. MicroRNA-518d regulates PPARI+ protein expression in the placentas of females with gestational diabetes mellitus. (PMID: 24639097) Zhao C. … Ling X. (Mol Med Rep 2014) 3 67
  2. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3

Products for MIR518D Gene

Sources for MIR518D Gene

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