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Aliases for MIR5187 Gene

Subcategory (RNA class) for MIR5187 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5187 Gene

  • MicroRNA 5187 2 3 5
  • Hsa-Mir-5187 3
  • Mir-5187 3

External Ids for MIR5187 Gene

Previous GeneCards Identifiers for MIR5187 Gene

  • GC01U903353
  • GC01P161199

Summaries for MIR5187 Gene

Entrez Gene Summary for MIR5187 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5187 Gene

MIR5187 (MicroRNA 5187) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5187 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5187 Gene

Genomics for MIR5187 Gene

Regulatory Elements for MIR5187 Gene

Enhancers for MIR5187 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H161222 1.1 ENCODE 0.7 -0.9 -888 6 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 B4GALT3 LOC100287049 DEDD TOMM40L NDUFS2 FCER1G MIR5187
GH01H161237 0.9 ENCODE 0.4 +11.2 11195 1 FOXA2 ATF1 ARID4B THRB RAD21 RARA YY1 CREM MIXL1 SP5 SDHC MPZ NECTIN4 NDUFS2 ADAMTS4 NR1I3 MIR5187
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5187 on UCSC Golden Path with GeneCards custom track

Promoters for MIR5187 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000014662 -986 801 PKNOX1 ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF143 ZNF207 FOS DEK

Genomic Location for MIR5187 Gene

Chromosome:
1
Start:
161,227,186 bp from pter
End:
161,227,261 bp from pter
Size:
76 bases
Orientation:
Plus strand

Genomic View for MIR5187 Gene

Genes around MIR5187 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5187 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5187 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5187 Gene

Proteins for MIR5187 Gene

Post-translational modifications for MIR5187 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5187 Gene

Domains & Families for MIR5187 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5187 Gene

Function for MIR5187 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5187
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5187 Gene

Localization for MIR5187 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5187 Gene

Pathways & Interactions for MIR5187 Gene

SuperPathways for MIR5187 Gene

No Data Available

Interacting Proteins for MIR5187 Gene

Gene Ontology (GO) - Biological Process for MIR5187 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5187 Gene

Drugs & Compounds for MIR5187 Gene

No Compound Related Data Available

Transcripts for MIR5187 Gene

mRNA/cDNA for MIR5187 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5187
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5187 Gene

No ASD Table

Relevant External Links for MIR5187 Gene

GeneLoc Exon Structure for
MIR5187
ECgene alternative splicing isoforms for
MIR5187

Expression for MIR5187 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5187 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5187 Gene:

MIR5187
genes like me logo Genes that share expression patterns with MIR5187: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5187 Gene

Orthologs for MIR5187 Gene

Evolution for MIR5187 Gene

ENSEMBL:
Gene Tree for MIR5187 (if available)
TreeFam:
Gene Tree for MIR5187 (if available)

No data available for Orthologs for MIR5187 Gene

Paralogs for MIR5187 Gene

No data available for Paralogs for MIR5187 Gene

Variants for MIR5187 Gene

Sequence variations from dbSNP and Humsavar for MIR5187 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002294447 -- 161,227,015(+) CATCT(C/T)CTCCT intron-variant, upstream-variant-2KB
rs1002296489 -- 161,226,268(+) ACAAG(A/T)GGGGG intron-variant, upstream-variant-2KB
rs1002363263 -- 161,227,479(+) TGAAT(-/GA)GAGAG intron-variant, downstream-variant-500B
rs1002514058 -- 161,225,225(+) TTGTC(C/T)CTGGT upstream-variant-2KB
rs1006446654 -- 161,227,752(+) GTTCC(C/T)GCCTC intron-variant, downstream-variant-500B

Relevant External Links for MIR5187 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5187

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5187 Gene

Disorders for MIR5187 Gene

Relevant External Links for MIR5187

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5187

No disorders were found for MIR5187 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5187 Gene

Publications for MIR5187 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 60
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce CE … Bowcock AM (Human molecular genetics 2011) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5187 Gene

Sources for MIR5187 Gene

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