Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR5186 Gene

Subcategory (RNA class) for MIR5186 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5186 Gene

  • MicroRNA 5186 2 3
  • Hsa-Mir-5186 3

External Ids for MIR5186 Gene

Summaries for MIR5186 Gene

Entrez Gene Summary for MIR5186 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5186 Gene

MIR5186 (MicroRNA 5186) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5186 Gene

Genomics for MIR5186 Gene

Genomic Location for MIR5186 Gene

Start:
151,565,876 bp from pter
End:
151,565,995 bp from pter
Size:
120 bases
Orientation:
Minus strand

Genomic View for MIR5186 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR5186 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5186 Gene

No data available for Regulatory Elements for MIR5186 Gene

Proteins for MIR5186 Gene

Post-translational modifications for MIR5186 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5186 Gene

Domains for MIR5186 Gene

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for MIR5186 Gene

Function for MIR5186 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR5186 Gene

Localization for MIR5186 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR5186 Gene

Pathways for MIR5186 Gene

SuperPathways for MIR5186 Gene

No Data Available

Interacting Proteins for MIR5186 Gene

Gene Ontology (GO) - Biological Process for MIR5186 Gene

None

No data available for Pathways by source for MIR5186 Gene

Transcripts for MIR5186 Gene

mRNA/cDNA for MIR5186 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5186 Gene

No ASD Table

Relevant External Links for MIR5186 Gene

GeneLoc Exon Structure for
MIR5186
ECgene alternative splicing isoforms for
MIR5186

Expression for MIR5186 Gene

mRNA expression in normal human tissues for MIR5186 Gene

genes like me logo Genes that share expressions with MIR5186: view

Orthologs for MIR5186 Gene

Evolution for MIR5186 Gene

ENSEMBL:
Gene Tree for MIR5186 (if available)
TreeFam:
Gene Tree for MIR5186 (if available)

No data available for Orthologs for MIR5186 Gene

Paralogs for MIR5186 Gene

No data available for Paralogs for MIR5186 Gene

Variants for MIR5186 Gene

Sequence variations from dbSNP and Humsavar for MIR5186 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs6776733 -- 151,566,928(+) GATGA(A/G)TCTCT upstream-variant-2KB
rs6804240 -- 151,567,876(+) CCACA(A/C/G)GCGAC upstream-variant-2KB
rs7623338 -- 151,567,461(+) ACCTA(C/T)TTGAA upstream-variant-2KB
rs7631281 -- 151,565,858(+) TGTAT(C/T)AATTA downstream-variant-500B
rs7635131 -- 151,567,515(+) GGGCC(C/T)CACAG upstream-variant-2KB

Relevant External Links for MIR5186 Gene

HapMap Linkage Disequilibrium report
MIR5186

No data available for Structural Variations from Database of Genomic Variants (DGV) for MIR5186 Gene

Disorders for MIR5186 Gene

No disorders were found for MIR5186 Gene.

No data available for UniProtKB/Swiss-Prot for MIR5186 Gene

Publications for MIR5186 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3

Products for MIR5186 Gene

Sources for MIR5186 Gene

Back to Top

Content