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Aliases for MIR5186 Gene

Subcategory (RNA class) for MIR5186 Gene


Quality Score for this RNA gene is


Aliases for MIR5186 Gene

  • MicroRNA 5186 2 3 5
  • Hsa-Mir-5186 3

External Ids for MIR5186 Gene

Previous GeneCards Identifiers for MIR5186 Gene

  • GC03U901832
  • GC03M151285

Summaries for MIR5186 Gene

Entrez Gene Summary for MIR5186 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5186 Gene

MIR5186 (MicroRNA 5186) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5186 Gene

Genomics for MIR5186 Gene

Regulatory Elements for MIR5186 Gene

Enhancers for MIR5186 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F151568 0.4 ENCODE 0.8 -2.4 -2393 0.2 PKNOX1 ATF2 MIR5186 IGSF10
GH03F151543 1 Ensembl ENCODE 0.3 +22.4 22394 0.4 SOX13 BACH1 ZNF316 NFE2 FOS MAFK TCF7L2 NFE2L2 SOX5 NFIA ENSG00000241151 IGSF10 MIR5186 ENSG00000242119
GH03F151580 0.6 ENCODE 0.4 -14.8 -14773 0.2 PKNOX1 JUND CEBPB STAT3 ZSCAN29 EP300 MIR5186 IGSF10
GH03F151537 0.8 Ensembl ENCODE 0.3 +27.6 27550 2.1 L3MBTL2 GATA2 RNF2 E2F6 MGA ENSG00000241151 IGSF10 MIR5186 ENSG00000242119
GH03F151550 0.5 ENCODE 0.3 +15.7 15688 0.0 JUND CEBPB EP300 ENSG00000241151 MIR5186 ENSG00000242119
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5186 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5186 Gene

151,565,876 bp from pter
151,565,995 bp from pter
120 bases
Minus strand

Genomic View for MIR5186 Gene

Genes around MIR5186 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5186 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5186 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5186 Gene

Proteins for MIR5186 Gene

Post-translational modifications for MIR5186 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5186 Gene

Domains & Families for MIR5186 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5186 Gene

Function for MIR5186 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5186 Gene

Localization for MIR5186 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5186 Gene

Pathways & Interactions for MIR5186 Gene

SuperPathways for MIR5186 Gene

No Data Available

Interacting Proteins for MIR5186 Gene

Gene Ontology (GO) - Biological Process for MIR5186 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5186 Gene

Transcripts for MIR5186 Gene

mRNA/cDNA for MIR5186 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5186 Gene

No ASD Table

Relevant External Links for MIR5186 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5186 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5186 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5186 Gene:

genes like me logo Genes that share expression patterns with MIR5186: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5186 Gene

Orthologs for MIR5186 Gene

Evolution for MIR5186 Gene

Gene Tree for MIR5186 (if available)
Gene Tree for MIR5186 (if available)

No data available for Orthologs for MIR5186 Gene

Paralogs for MIR5186 Gene

No data available for Paralogs for MIR5186 Gene

Variants for MIR5186 Gene

Sequence variations from dbSNP and Humsavar for MIR5186 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs111348710 -- 151,566,504(+) TGTCC(C/T)TGCTT intron-variant, upstream-variant-2KB
rs113817542 -- 151,566,116(+) ATGTC(A/T)TGAGA intron-variant, upstream-variant-2KB
rs114151035 -- 151,565,818(+) AGATA(C/T)GAGAG intron-variant, downstream-variant-500B
rs116451337 -- 151,566,131(+) CCTGG(C/T)AGAGG intron-variant, upstream-variant-2KB
rs116766791 -- 151,567,363(+) TCTGC(G/T)GAGAG intron-variant, upstream-variant-2KB

Relevant External Links for MIR5186 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5186 Gene

Disorders for MIR5186 Gene

Relevant External Links for MIR5186

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5186 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5186 Gene

Publications for MIR5186 Gene

  1. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5186 Gene

Sources for MIR5186 Gene

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