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Aliases for MIR5186 Gene

Subcategory (RNA class) for MIR5186 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5186 Gene

  • MicroRNA 5186 2 3 5
  • Hsa-Mir-5186 3

External Ids for MIR5186 Gene

Previous GeneCards Identifiers for MIR5186 Gene

  • GC03U901832
  • GC03M151285

Summaries for MIR5186 Gene

Entrez Gene Summary for MIR5186 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5186 Gene

MIR5186 (MicroRNA 5186) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5186 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5186 Gene

Genomics for MIR5186 Gene

GeneHancer (GH) Regulatory Elements for MIR5186 Gene

Promoters and enhancers for MIR5186 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03I151568 Enhancer 0.4 ENCODE 0.8 -2.4 -2393 0.2 ZNF335 PKNOX1 ATF2 MIR5186 IGSF10
GH03I151580 Enhancer 0.7 Ensembl ENCODE 0.4 -14.7 -14726 0.2 MEIS2 JUND PKNOX1 STAT3 CEBPB ZSCAN29 EP300 MIR5186 IGSF10
GH03I151537 Enhancer 0.8 Ensembl ENCODE 0.3 +27.6 27550 2.1 USF1 RNF2 L3MBTL2 MZF1 REST ZNF592 POLR2A GMEB1 MGA LINC02066 IGSF10 MIR5186 ENSG00000242119
GH03I151543 Enhancer 0.7 Ensembl 0.3 +22.5 22494 0.2 SOX13 NFIB BACH1 ZNF316 NFE2 FOS TCF7L2 ZNF639 SOX5 NFIA LINC02066 MIR5186 ENSG00000242119 IGSF10
GH03I151544 Enhancer 0.7 ENCODE 0.3 +22.3 22297 0.1 SOX13 NFIB BACH1 ZNF316 NFE2 FOS MAFK TCF7L2 NFE2L2 ZNF639 LINC02066 IGSF10 MIR5186 ENSG00000242119
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5186 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5186 Gene

Genomic Locations for MIR5186 Gene
chr3:151,565,876-151,565,995
(GRCh38/hg38)
Size:
120 bases
Orientation:
Minus strand
chr3:151,283,664-151,283,783
(GRCh37/hg19)

Genomic View for MIR5186 Gene

Genes around MIR5186 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5186 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5186 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5186 Gene

Proteins for MIR5186 Gene

Post-translational modifications for MIR5186 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5186 Gene

Domains & Families for MIR5186 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5186 Gene

Function for MIR5186 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5186 Gene

Localization for MIR5186 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5186 Gene

Pathways & Interactions for MIR5186 Gene

SuperPathways for MIR5186 Gene

No Data Available

Interacting Proteins for MIR5186 Gene

Gene Ontology (GO) - Biological Process for MIR5186 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5186 Gene

Drugs & Compounds for MIR5186 Gene

No Compound Related Data Available

Transcripts for MIR5186 Gene

mRNA/cDNA for MIR5186 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5186 Gene

No ASD Table

Relevant External Links for MIR5186 Gene

GeneLoc Exon Structure for
MIR5186
ECgene alternative splicing isoforms for
MIR5186

Expression for MIR5186 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5186 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5186 Gene:

MIR5186
genes like me logo Genes that share expression patterns with MIR5186: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5186 Gene

Orthologs for MIR5186 Gene

Evolution for MIR5186 Gene

ENSEMBL:
Gene Tree for MIR5186 (if available)
TreeFam:
Gene Tree for MIR5186 (if available)

No data available for Orthologs for MIR5186 Gene

Paralogs for MIR5186 Gene

No data available for Paralogs for MIR5186 Gene

Variants for MIR5186 Gene

Sequence variations from dbSNP and Humsavar for MIR5186 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1003455426 -- 151,566,745(-) G/A upstream_transcript_variant
rs1003552829 -- 151,566,100(-) G/A upstream_transcript_variant
rs1006720565 -- 151,567,001(-) G/A upstream_transcript_variant
rs1006807341 -- 151,567,419(-) T/C upstream_transcript_variant
rs1006815449 -- 151,566,812(-) T/C upstream_transcript_variant

Additional Variant Information for MIR5186 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5186

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR5186 Gene

Disorders for MIR5186 Gene

Additional Disease Information for MIR5186

No disorders were found for MIR5186 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5186 Gene

Publications for MIR5186 Gene

  1. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5186 Gene

Sources for MIR5186 Gene

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