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Aliases for MIR514B Gene

Subcategory (RNA class) for MIR514B Gene


Quality Score for this RNA gene is


Aliases for MIR514B Gene

  • MicroRNA 514b 2 3
  • Hsa-Mir-514b 3

External Ids for MIR514B Gene

Previous GeneCards Identifiers for MIR514B Gene

  • GC0XU901654
  • GC0XM135293
  • GC0XM146332
  • GC0XM146336

Summaries for MIR514B Gene

Entrez Gene Summary for MIR514B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR514B Gene

MIR514B (MicroRNA 514b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR514B Gene

Genomics for MIR514B Gene

Genomic Location for MIR514B Gene

147,250,151 bp from pter
147,250,230 bp from pter
80 bases
Minus strand

Genomic View for MIR514B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR514B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR514B Gene

No data available for Regulatory Elements for MIR514B Gene

Proteins for MIR514B Gene

Post-translational modifications for MIR514B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR514B Gene

Domains for MIR514B Gene

Gene Families for MIR514B Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR514B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR514B Gene

Function for MIR514B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR514B Gene

Localization for MIR514B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR514B Gene

Pathways for MIR514B Gene

SuperPathways for MIR514B Gene

No Data Available

Interacting Proteins for MIR514B Gene

Gene Ontology (GO) - Biological Process for MIR514B Gene


No data available for Pathways by source for MIR514B Gene

Transcripts for MIR514B Gene

mRNA/cDNA for MIR514B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR514B Gene

No ASD Table

Relevant External Links for MIR514B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR514B Gene

mRNA expression in normal human tissues for MIR514B Gene

genes like me logo Genes that share expressions with MIR514B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR514B Gene

Orthologs for MIR514B Gene

Evolution for MIR514B Gene

Gene Tree for MIR514B (if available)
Gene Tree for MIR514B (if available)

No data available for Orthologs for MIR514B Gene

Paralogs for MIR514B Gene

No data available for Paralogs for MIR514B Gene

Variants for MIR514B Gene

Sequence variations from dbSNP and Humsavar for MIR514B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs6626862 -- 147,249,828(+) GCTAC(A/G)GTTGG downstream-variant-500B
rs12391466 -- 147,251,308(+) ATGGA(C/T)GTCAG upstream-variant-2KB
rs12848355 -- 147,250,490(+) caaat(A/T)tccag upstream-variant-2KB
rs12848364 -- 147,250,491(+) aaatt(G/T)ccagt upstream-variant-2KB
rs73600095 -- 147,249,795(+) ATGTC(A/G)ATAGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR514B Gene

Variant ID Type Subtype PubMed ID
dgv2488e1 CNV Complex 17122850
esv35128 CNV Gain 17911159
nsv521982 CNV Gain 19592680
nsv508808 CNV Insertion 20534489

Relevant External Links for MIR514B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR514B Gene

Disorders for MIR514B Gene

No disorders were found for MIR514B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR514B Gene

Publications for MIR514B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton C.J. … Gunaratne P.H. (PLoS ONE 2010) 3
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3
  4. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D. … Lui W.O. (BMC Biol. 2010) 3
  5. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR514B Gene

Sources for MIR514B Gene

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