Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR513A2 Gene

Subcategory (RNA class) for MIR513A2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR513A2 Gene

  • MicroRNA 513a-2 2 3
  • MicroRNA 513-2 2 3
  • Hsa-Mir-513a-2 3
  • Hsa-Mir-513-2 3
  • MIRN513A-2 3
  • MIRN513-2 3
  • MIRN513A2 3

External Ids for MIR513A2 Gene

Previous HGNC Symbols for MIR513A2 Gene

  • MIRN513-2
  • MIRN513A-2
  • MIRN513A2

Previous GeneCards Identifiers for MIR513A2 Gene

  • GC0XM146117
  • GC0XM146307

Summaries for MIR513A2 Gene

Entrez Gene Summary for MIR513A2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR513A2 Gene

MIR513A2 (MicroRNA 513a-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR513A2 Gene

Genomics for MIR513A2 Gene

Genomic Location for MIR513A2 Gene

Start:
147,225,826 bp from pter
End:
147,225,952 bp from pter
Size:
127 bases
Orientation:
Minus strand

Genomic View for MIR513A2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR513A2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR513A2 Gene

No data available for Regulatory Elements for MIR513A2 Gene

Proteins for MIR513A2 Gene

Post-translational modifications for MIR513A2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR513A2 Gene

Domains for MIR513A2 Gene

Gene Families for MIR513A2 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR513A2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR513A2 Gene

Function for MIR513A2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR513A2 Gene

Localization for MIR513A2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR513A2 Gene

Pathways for MIR513A2 Gene

SuperPathways for MIR513A2 Gene

No Data Available

Interacting Proteins for MIR513A2 Gene

Gene Ontology (GO) - Biological Process for MIR513A2 Gene

None

No data available for Pathways by source for MIR513A2 Gene

Transcripts for MIR513A2 Gene

mRNA/cDNA for MIR513A2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR513A2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR513A2 Gene

No ASD Table

Relevant External Links for MIR513A2 Gene

GeneLoc Exon Structure for
MIR513A2
ECgene alternative splicing isoforms for
MIR513A2

Expression for MIR513A2 Gene

mRNA expression in normal human tissues for MIR513A2 Gene

genes like me logo Genes that share expressions with MIR513A2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR513A2 Gene

Orthologs for MIR513A2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR513A2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-513a-3 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR513A2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR513A2 Gene

ENSEMBL:
Gene Tree for MIR513A2 (if available)
TreeFam:
Gene Tree for MIR513A2 (if available)

Paralogs for MIR513A2 Gene

No data available for Paralogs for MIR513A2 Gene

Variants for MIR513A2 Gene

Sequence variations from dbSNP and Humsavar for MIR513A2 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2018562 -- 147,225,643(+) CTCAT(C/T)TGGCA downstream-variant-500B
rs2018598 -- 147,226,178(-) atcac(A/G)ccaat upstream-variant-2KB
rs2018600 -- 147,226,187(-) tgagc(C/T)gagat upstream-variant-2KB
rs3037717 -- 147,226,834(+) tgtgt(-/GT)GATGT upstream-variant-2KB
rs9698651 -- 147,226,793(+) TAtgt(A/G)tgtgt upstream-variant-2KB

Relevant External Links for MIR513A2 Gene

HapMap Linkage Disequilibrium report
MIR513A2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR513A2 Gene

Disorders for MIR513A2 Gene

No disorders were found for MIR513A2 Gene.

No data available for UniProtKB/Swiss-Prot for MIR513A2 Gene

Publications for MIR513A2 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. MicroRNA miR-513a-3p acts as a co-regulator of luteinizing hormone/chorionic gonadotropin receptor gene expression in human granulosa cells. (PMID: 24747085) Troppmann B. … Gromoll J. (Mol. Cell. Endocrinol. 2014) 3

Products for MIR513A2 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR513A2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR513A2
    • Block miRNA regulation of MIR513A2 using miScript Target Protectors

    Sources for MIR513A2 Gene

    Back to Top

    Content