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MIR513A1 Gene(RNA Gene)

MicroRNA 513a-1

GCID:
GC0XM147213
GIFtS:
13
Genes Participants
UDN Logo

Aliases for MIR513A1 Gene

Subcategory (RNA class) for MIR513A1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR513A1 Gene

  • MicroRNA 513a-1 2 3 5
  • MicroRNA 513-1 2 3
  • Hsa-Mir-513a-1 3
  • Hsa-Mir-513-1 3
  • MIRN513-1 3
  • MIRN513A1 3

External Ids for MIR513A1 Gene

ORGUL Members for MIR513A1 Gene

Previous HGNC Symbols for MIR513A1 Gene

  • MIRN513-1
  • MIRN513A1

Previous GeneCards Identifiers for MIR513A1 Gene

  • GC0XM146104
  • GC0XM146294

Summaries for MIR513A1 Gene

Entrez Gene Summary for MIR513A1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR513A1 Gene

MIR513A1 (MicroRNA 513a-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR513A1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR513A1 Gene

Genomics for MIR513A1 Gene

Products:

  1. Regulatory Element

Genomic Locations for MIR513A1 Gene

Genomic Locations for MIR513A1 Gene
chrX:147,213,463-147,213,591
(GRCh38/hg38)
Size:
129 bases
Orientation:
Minus strand
chrX:146,294,981-146,295,109
(GRCh37/hg19)

Genomic View for MIR513A1 Gene

Genes around MIR513A1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR513A1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR513A1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR513A1 Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR513A1 Gene

Proteins for MIR513A1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR513A1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR513A1 Gene

Domains & Families for MIR513A1 Gene

Gene Families for MIR513A1 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR513A1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR513A1 Gene

Function for MIR513A1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR513A1 Gene

Localization for MIR513A1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR513A1 Gene

Pathways & Interactions for MIR513A1 Gene

SuperPathways for MIR513A1 Gene

PathCards logo More details on SuperPathways for MIR513A1
No Data Available

Interacting Proteins for MIR513A1 Gene

Gene Ontology (GO) - Biological Process for MIR513A1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR513A1 Gene

Drugs & Compounds for MIR513A1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR513A1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR513A1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR513A1 Gene

No ASD Table

Relevant External Links for MIR513A1 Gene

GeneLoc Exon Structure for
MIR513A1
ECgene alternative splicing isoforms for
MIR513A1

Expression for MIR513A1 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR513A1 Gene

mRNA expression in normal human tissues for MIR513A1 Gene
mRNA expression by GTEx for MIR513A1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR513A1 Gene:

MIR513A1
genes like me logo Genes that share expression patterns with MIR513A1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR513A1 Gene

Orthologs for MIR513A1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR513A1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia ptr-mir-513a-2 34
  • 95 (a)
 OneToOne
Species where no ortholog for MIR513A1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR513A1 Gene

ENSEMBL:
Gene Tree for MIR513A1 (if available)
TreeFam:
Gene Tree for MIR513A1 (if available)

Paralogs for MIR513A1 Gene

No data available for Paralogs for MIR513A1 Gene

Variants for MIR513A1 Gene

Sequence variations from dbSNP and Humsavar for MIR513A1 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1001086334 -- 147,213,139(-) C/T downstream_transcript_variant
rs1003217748 -- 147,214,492(-) T/C upstream_transcript_variant
rs1006875374 -- 147,213,780(-) G/C upstream_transcript_variant
rs1007303308 -- 147,213,805(-) A/C upstream_transcript_variant
rs1010344962 -- 147,213,169(-) G/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR513A1 Gene

Variant ID Type Subtype PubMed ID
esv2740574 CNV deletion 23290073
esv2758898 CNV gain 17122850
esv35128 CNV gain 17911159

Additional Variant Information for MIR513A1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR513A1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR513A1 Gene

Disorders for MIR513A1 Gene

Additional Disease Information for MIR513A1

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR513A1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR513A1 Gene

Publications for MIR513A1 Gene

  1. Upregulation of miR-513b inhibits cell proliferation, migration, and promotes apoptosis by targeting high mobility group-box 3 protein in gastric cancer. (PMID: 25095979) Chen X … Song G (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014) 3 58
  2. MicroRNA miR-513a-3p acts as a co-regulator of luteinizing hormone/chorionic gonadotropin receptor gene expression in human granulosa cells. (PMID: 24747085) Troppmann B … Gromoll J (Molecular and cellular endocrinology 2014) 3 58
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58
  5. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I … Bentwich Z (Nature genetics 2005) 3 58

Products for MIR513A1 Gene

Sources for MIR513A1 Gene

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