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Aliases for MIR512-2 Gene

Subcategory (RNA class) for MIR512-2 Gene


Quality Score for this RNA gene is


Aliases for MIR512-2 Gene

  • MicroRNA 512-2 2 3
  • Hsa-Mir-512-2 3
  • MIRN512-2 3

External Ids for MIR512-2 Gene

ORGUL Members for MIR512-2 Gene

Previous HGNC Symbols for MIR512-2 Gene

  • MIRN512-2

Previous GeneCards Identifiers for MIR512-2 Gene

  • GC19P058865
  • GC19P054172

Summaries for MIR512-2 Gene

Entrez Gene Summary for MIR512-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR512-2 Gene

MIR512-2 (MicroRNA 512-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR512-2 Gene

Genomics for MIR512-2 Gene

Genomic Location for MIR512-2 Gene

53,669,157 bp from pter
53,669,254 bp from pter
98 bases
Plus strand

Genomic View for MIR512-2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR512-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR512-2 Gene

No data available for Regulatory Elements for MIR512-2 Gene

Proteins for MIR512-2 Gene

Post-translational modifications for MIR512-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR512-2 Gene

Domains for MIR512-2 Gene

Gene Families for MIR512-2 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR512-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR512-2 Gene

Function for MIR512-2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR512-2 Gene

Localization for MIR512-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR512-2 Gene

Pathways for MIR512-2 Gene

SuperPathways for MIR512-2 Gene

No Data Available

Interacting Proteins for MIR512-2 Gene

Gene Ontology (GO) - Biological Process for MIR512-2 Gene


No data available for Pathways by source for MIR512-2 Gene

Transcripts for MIR512-2 Gene

mRNA/cDNA for MIR512-2 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MIR512-2

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR512-2 Gene

No ASD Table

Relevant External Links for MIR512-2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR512-2 Gene

mRNA expression in normal human tissues for MIR512-2 Gene

genes like me logo Genes that share expressions with MIR512-2: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR512-2 Gene

Orthologs for MIR512-2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR512-2 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 36
  • 22 (a)
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
Species with no ortholog for MIR512-2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR512-2 Gene

Gene Tree for MIR512-2 (if available)
Gene Tree for MIR512-2 (if available)

Paralogs for MIR512-2 Gene

No data available for Paralogs for MIR512-2 Gene

Variants for MIR512-2 Gene

Sequence variations from dbSNP and Humsavar for MIR512-2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs1968439 -- 53,669,063(-) AATAG(C/T)GAAAG upstream-variant-2KB
rs7253932 -- 53,667,660(+) Tggca(A/G)gacgc upstream-variant-2KB
rs7254473 -- 53,668,056(+) TTGCC(G/T)CTCTG upstream-variant-2KB
rs7254488 -- 53,668,103(+) AACAA(A/G)AAGTT upstream-variant-2KB
rs7255095 -- 53,668,051(+) CTGTG(C/T)TGCCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR512-2 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv912385 CNV Gain 21882294
dgv3999n71 CNV Gain 21882294
esv5886 CNV Loss 19470904

Relevant External Links for MIR512-2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR512-2 Gene

Disorders for MIR512-2 Gene

No disorders were found for MIR512-2 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR512-2 Gene

Publications for MIR512-2 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Chromatin remodeling at Alu repeats by epigenetic treatment activates silenced microRNA-512-5p with downregulation of Mcl-1 in human gastric cancer cells. (PMID: 19503096) Saito Y. … Hibi T. (Oncogene 2009) 3
  5. Inhibition of c-FLIP expression by miR-512-3p contributes to taxol-induced apoptosis in hepatocellular carcinoma cells. (PMID: 20372864) Chen F. … Chen Z. (Oncol. Rep. 2010) 3

Products for MIR512-2 Gene

Sources for MIR512-2 Gene

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