Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR510 Gene

Subcategory (RNA class) for MIR510 Gene


Quality Score for this RNA gene is


Aliases for MIR510 Gene

  • MicroRNA 510 2 3
  • Hsa-Mir-510 3
  • MIRN510 3

External Ids for MIR510 Gene

Previous HGNC Symbols for MIR510 Gene

  • MIRN510

Previous GeneCards Identifiers for MIR510 Gene

  • GC0XM146162
  • GC0XM146353

Summaries for MIR510 Gene

Entrez Gene Summary for MIR510 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR510 Gene

MIR510 (MicroRNA 510) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR510 include irritable bowel syndrome.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR510 Gene

Genomics for MIR510 Gene

Genomic Location for MIR510 Gene

147,272,335 bp from pter
147,272,408 bp from pter
74 bases
Minus strand

Genomic View for MIR510 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR510 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR510 Gene

No data available for Regulatory Elements for MIR510 Gene

Proteins for MIR510 Gene

Post-translational modifications for MIR510 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR510 Gene

Domains for MIR510 Gene

Gene Families for MIR510 Gene

  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR510: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR510 Gene

Function for MIR510 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR510 Gene

Localization for MIR510 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR510 Gene

Pathways for MIR510 Gene

SuperPathways for MIR510 Gene

No Data Available

Interacting Proteins for MIR510 Gene

Gene Ontology (GO) - Biological Process for MIR510 Gene


No data available for Pathways by source for MIR510 Gene

Transcripts for MIR510 Gene

mRNA/cDNA for MIR510 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR510 Gene

No ASD Table

Relevant External Links for MIR510 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR510 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR510 Gene

Orthologs for MIR510 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR510 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 36
  • 67 (a)
(Pan troglodytes)
Mammalia ptr-mir-510 36
  • 72 (a)
Species with no ortholog for MIR510:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR510 Gene

Gene Tree for MIR510 (if available)
Gene Tree for MIR510 (if available)

Paralogs for MIR510 Gene

No data available for Paralogs for MIR510 Gene

Variants for MIR510 Gene

Sequence variations from dbSNP and Humsavar for MIR510 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1447392 -- 147,272,242(-) GTACC(C/G)TCCTC downstream-variant-500B
rs1447393 -- 147,272,022(-) CCTGC(C/G)GGGTC downstream-variant-500B
rs1447394 -- 147,271,971(-) CTCAG(A/C)CACAG downstream-variant-500B
rs5904728 -- 147,272,507(+) TGGCC(A/G)TTGGC upstream-variant-2KB
rs5905028 -- 147,272,508(+) GGCCG(C/T)TGGCA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR510 Gene

Variant ID Type Subtype PubMed ID
dgv2488e1 CNV Complex 17122850
esv35128 CNV Gain 17911159
nsv521982 CNV Gain 19592680
nsv508808 CNV Insertion 20534489
nsv7138 CNV Insertion 18451855
nsv216 CNV Insertion 15895083

Relevant External Links for MIR510 Gene

HapMap Linkage Disequilibrium report
Human Gene Mutation Database (HGMD)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR510 Gene

Disorders for MIR510 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR510 Gene in MalaCards »

(1) Diseases for MIR510 Gene including...

genes like me logo Genes that share disorders with MIR510: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR510 Gene

Publications for MIR510 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome. (PMID: 18614545) Kapeller J. … Niesler B. (Hum. Mol. Genet. 2008) 3
  5. microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients. (PMID: 19954774) Hezova R. … Michalek J. (Cell. Immunol. 2010) 3

Products for MIR510 Gene

Sources for MIR510 Gene

Back to Top