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Aliases for MIR510 Gene

Subcategory (RNA class) for MIR510 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR510 Gene

  • MicroRNA 510 2 3 5
  • Hsa-Mir-510 3
  • Mir-510 3
  • MIRN510 3

External Ids for MIR510 Gene

Previous HGNC Symbols for MIR510 Gene

  • MIRN510

Previous GeneCards Identifiers for MIR510 Gene

  • GC0XM146162
  • GC0XM146353

Summaries for MIR510 Gene

Entrez Gene Summary for MIR510 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR510 Gene

MIR510 (MicroRNA 510) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR510 Gene

Genomics for MIR510 Gene

Genomic Location for MIR510 Gene

Chromosome:
X
Start:
147,272,335 bp from pter
End:
147,272,408 bp from pter
Size:
74 bases
Orientation:
Minus strand

Genomic View for MIR510 Gene

Genes around MIR510 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR510 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR510 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR510 Gene

No data available for Regulatory Elements for MIR510 Gene

Proteins for MIR510 Gene

Post-translational modifications for MIR510 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR510 Gene

Domains & Families for MIR510 Gene

Gene Families for MIR510 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR510: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR510 Gene

Function for MIR510 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR510 Gene

Localization for MIR510 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR510 Gene

Pathways & Interactions for MIR510 Gene

SuperPathways for MIR510 Gene

No Data Available

Interacting Proteins for MIR510 Gene

Gene Ontology (GO) - Biological Process for MIR510 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR510 Gene

Drugs & Compounds for MIR510 Gene

No Compound Related Data Available

Transcripts for MIR510 Gene

mRNA/cDNA for MIR510 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR510 Gene

No ASD Table

Relevant External Links for MIR510 Gene

GeneLoc Exon Structure for
MIR510
ECgene alternative splicing isoforms for
MIR510

Expression for MIR510 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR510 Gene

Orthologs for MIR510 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR510 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 36
  • 67 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-510 36
  • 72 (a)
OneToOne
Species with no ortholog for MIR510:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR510 Gene

ENSEMBL:
Gene Tree for MIR510 (if available)
TreeFam:
Gene Tree for MIR510 (if available)

Paralogs for MIR510 Gene

No data available for Paralogs for MIR510 Gene

Variants for MIR510 Gene

Sequence variations from dbSNP and Humsavar for MIR510 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs5904728 -- 147,272,507(+) TGGCC(A/G)TTGGC upstream-variant-2KB
rs5905028 -- 147,272,508(+) GGCCG(C/T)TGGCA upstream-variant-2KB
rs5905029 -- 147,272,668(+) TCATT(C/G/T)GATGC upstream-variant-2KB
rs5905030 -- 147,272,710(+) TAAAG(C/T)ATTAA upstream-variant-2KB
rs5905031 -- 147,272,833(+) AACTC(C/T)TCACT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR510 Gene

Variant ID Type Subtype PubMed ID
dgv2488e1 CNV Complex 17122850
esv35128 CNV Gain 17911159
nsv521982 CNV Gain 19592680
nsv508808 CNV Insertion 20534489
nsv7138 CNV Insertion 18451855
nsv216 CNV Insertion 15895083

Relevant External Links for MIR510 Gene

Human Gene Mutation Database (HGMD)
MIR510

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR510 Gene

Disorders for MIR510 Gene

Relevant External Links for MIR510

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR510

No disorders were found for MIR510 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR510 Gene

Publications for MIR510 Gene

  1. MicroRNA-510 promotes cell and tumor growth by targeting peroxiredoxin1 in breast cancer. (PMID: 23971998) Guo Q.J. … Findlay V.J. (Breast Cancer Res. 2013) 3 67
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  4. microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients. (PMID: 19954774) Hezova R. … Michalek J. (Cell. Immunol. 2010) 3
  5. First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome. (PMID: 18614545) Kapeller J. … Niesler B. (Hum. Mol. Genet. 2008) 3

Products for MIR510 Gene

Sources for MIR510 Gene

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