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Aliases for MIR5093 Gene

Subcategory (RNA class) for MIR5093 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR5093 Gene

  • MicroRNA 5093 2 3 5
  • Hsa-Mir-5093 3

External Ids for MIR5093 Gene

Previous GeneCards Identifiers for MIR5093 Gene

  • GC16U901380
  • GC16M085342

Summaries for MIR5093 Gene

Entrez Gene Summary for MIR5093 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5093 Gene

MIR5093 (MicroRNA 5093) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5093 Gene

Genomics for MIR5093 Gene

Regulatory Elements for MIR5093 Gene

Enhancers for MIR5093 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16F085302 0.9 FANTOM5 Ensembl ENCODE 0.8 -2.3 -2346 12.7 HDGF PKNOX1 CREB3L1 ARNT MLX ZFP64 ARID4B SIN3A DMAP1 YBX1 ENSG00000261243 ENSG00000260859 ENSG00000269898 ENSG00000261177 ENSG00000260504 KLHL36 ENSG00000270184 CRISPLD2 RN7SL381P FAM92B
GH16F085301 0.2 ENCODE 0.8 +4.8 4790 0.9 PKNOX1 ARNT SIN3A YY1 ZNF121 GLIS2 ZNF766 GATA2 NCOA1 CREB3 MIR5093 LINC00311
GH16F085303 0.4 ENCODE 0.8 +4.2 4156 0.2 EGR2 ZBTB2 NCOA1 CEBPB ZEB2 MBD2 ZNF589 SMARCA4 PBX2 IKZF1 MIR5093 LINC00311
GH16F085297 0.2 ENCODE 0.4 +8.9 8916 0.2 HDGF PKNOX1 ARNT SIN3A ARID4B FEZF1 GLIS2 ZNF143 ZNF263 REST MIR5093 LINC00311
GH16F085285 0.8 Ensembl ENCODE 0.3 +19.6 19583 2.3 PKNOX1 YY1 EGR2 SMARCA5 REST ZNF623 NR2F2 TFDP1 SMARCA4 PBX2 LOC105371374 LINC00311 MIR5093
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5093 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5093 Gene

Chromosome:
16
Start:
85,306,226 bp from pter
End:
85,306,325 bp from pter
Size:
100 bases
Orientation:
Minus strand

Genomic View for MIR5093 Gene

Genes around MIR5093 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5093 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5093 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5093 Gene

ORGUL Member Location for MIR5093 Gene

ORGUL Member Location for MIR5093 gene

Proteins for MIR5093 Gene

Post-translational modifications for MIR5093 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5093 Gene

Domains & Families for MIR5093 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5093 Gene

Function for MIR5093 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5093 Gene

Localization for MIR5093 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5093 Gene

Pathways & Interactions for MIR5093 Gene

SuperPathways for MIR5093 Gene

No Data Available

Interacting Proteins for MIR5093 Gene

Gene Ontology (GO) - Biological Process for MIR5093 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5093 Gene

Transcripts for MIR5093 Gene

mRNA/cDNA for MIR5093 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5093 Gene

No ASD Table

Relevant External Links for MIR5093 Gene

GeneLoc Exon Structure for
MIR5093
ECgene alternative splicing isoforms for
MIR5093

Expression for MIR5093 Gene

mRNA expression in normal human tissues for MIR5093 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5093 Gene:

MIR5093
genes like me logo Genes that share expression patterns with MIR5093: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5093 Gene

Orthologs for MIR5093 Gene

Evolution for MIR5093 Gene

ENSEMBL:
Gene Tree for MIR5093 (if available)
TreeFam:
Gene Tree for MIR5093 (if available)

No data available for Orthologs for MIR5093 Gene

Paralogs for MIR5093 Gene

No data available for Paralogs for MIR5093 Gene

Variants for MIR5093 Gene

Sequence variations from dbSNP and Humsavar for MIR5093 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs112238963 -- 85,307,613(+) GCACA(C/G)AGCAT intron-variant, nc-transcript-variant, upstream-variant-2KB
rs114280915 -- 85,307,070(+) GCTGA(A/G)TTTGG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs12927290 -- 85,308,107(+) ATGGA(A/C)TTCAG intron-variant, upstream-variant-2KB
rs139034502 -- 85,307,389(+) GCCCC(A/C)GGACA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs140105649 -- 85,307,611(+) GGCAC(-/CAGA)ACAGC intron-variant, nc-transcript-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5093 Gene

Variant ID Type Subtype PubMed ID
nsv483044 CNV gain 15286789
nsv833312 CNV loss 17160897
nsv833313 CNV loss 17160897
nsv952062 CNV deletion 24416366

Relevant External Links for MIR5093 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5093

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5093 Gene

Disorders for MIR5093 Gene

Relevant External Links for MIR5093

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5093

No disorders were found for MIR5093 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5093 Gene

Publications for MIR5093 Gene

  1. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N. … Zhou G. (J. Radiat. Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5093 Gene

Sources for MIR5093 Gene

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