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Aliases for MIR5090 Gene

Subcategory (RNA class) for MIR5090 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5090 Gene

  • MicroRNA 5090 2 3 5
  • Hsa-Mir-5090 3
  • Mir-5090 3

External Ids for MIR5090 Gene

Previous GeneCards Identifiers for MIR5090 Gene

  • GC07U903236
  • GC07P102110
  • GC07P102122

Summaries for MIR5090 Gene

Entrez Gene Summary for MIR5090 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5090 Gene

MIR5090 (MicroRNA 5090) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5090 Gene

Genomics for MIR5090 Gene

Regulatory Elements for MIR5090 Gene

Enhancers for MIR5090 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G102463 1.1 ENCODE 0.7 -0.7 -689 2.1 HDGF PKNOX1 CREB3L1 AGO1 ARID4B SIN3A ZBTB7B YY1 ZNF766 ZNF207 POLR2J ORAI2 RASA4DP GC07P102467 PIR43748 MIR5090
GH07G102467 0.7 ENCODE 0.7 +1.6 1608 0.1 HDGF CTCF ZSCAN4 ZNF501 ZNF398 RAD21 ZFHX2 POLR2A TARDBP IKZF1 MIR5090 MIR4467
GH07G102470 0.6 ENCODE 0.7 +4.9 4887 0.2 CTCF MAX ZNF623 GABPA YY1 HNF4G PRDM10 HNF4A HNRNPL MIR548O PRKRIP1 MIR5090 MIR4467
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5090 on UCSC Golden Path with GeneCards custom track

Promoters for MIR5090 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000216102 -742 1601 HDGF PKNOX1 CREB3L1 AGO1 ARID4B SIN3A ZBTB7B YY1 ZNF766 ZNF207

Genomic Location for MIR5090 Gene

Chromosome:
7
Start:
102,465,742 bp from pter
End:
102,465,826 bp from pter
Size:
85 bases
Orientation:
Plus strand

Genomic View for MIR5090 Gene

Genes around MIR5090 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5090 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5090 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5090 Gene

Proteins for MIR5090 Gene

Post-translational modifications for MIR5090 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5090 Gene

Domains & Families for MIR5090 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5090 Gene

Function for MIR5090 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5090 Gene

Localization for MIR5090 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5090 Gene

Pathways & Interactions for MIR5090 Gene

SuperPathways for MIR5090 Gene

No Data Available

Interacting Proteins for MIR5090 Gene

Gene Ontology (GO) - Biological Process for MIR5090 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5090 Gene

Drugs & Compounds for MIR5090 Gene

No Compound Related Data Available

Transcripts for MIR5090 Gene

mRNA/cDNA for MIR5090 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5090 Gene

No ASD Table

Relevant External Links for MIR5090 Gene

GeneLoc Exon Structure for
MIR5090
ECgene alternative splicing isoforms for
MIR5090

Expression for MIR5090 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5090 Gene

mRNA differential expression in normal tissues according to GTEx for MIR5090 Gene

This gene is overexpressed in Testis (x17.3).

NURSA nuclear receptor signaling pathways regulating expression of MIR5090 Gene:

MIR5090
genes like me logo Genes that share expression patterns with MIR5090: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5090 Gene

Orthologs for MIR5090 Gene

Evolution for MIR5090 Gene

ENSEMBL:
Gene Tree for MIR5090 (if available)
TreeFam:
Gene Tree for MIR5090 (if available)

No data available for Orthologs for MIR5090 Gene

Paralogs for MIR5090 Gene

No data available for Paralogs for MIR5090 Gene

Variants for MIR5090 Gene

Sequence variations from dbSNP and Humsavar for MIR5090 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000046552 -- 102,463,744(+) TCCTT(C/T)GGATA intron-variant, upstream-variant-2KB
rs1002390196 -- 102,465,153(+) TCCGG(A/T)GTCTG upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs1006113348 -- 102,464,493(+) CCCCC(A/G)GAGTC intron-variant, upstream-variant-2KB
rs1006678947 -- 102,464,942(+) CCGGT(A/C)GTTAA upstream-variant-2KB, utr-variant-5-prime
rs1007269255 -- 102,466,053(+) GACGG(C/T)AAGTG downstream-variant-500B, upstream-variant-2KB, splice-donor-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5090 Gene

Variant ID Type Subtype PubMed ID
dgv11540n54 CNV loss 21841781
dgv6538n100 CNV gain 25217958
nsv428182 CNV gain 18775914
nsv464664 CNV gain 19166990
nsv464665 CNV loss 19166990
nsv5879 CNV deletion 18451855
nsv607998 CNV gain+loss 21841781
nsv607999 CNV loss 21841781
nsv608003 CNV gain 21841781
nsv8192 CNV gain 18304495
nsv831083 CNV loss 17160897

Relevant External Links for MIR5090 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5090

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5090 Gene

Disorders for MIR5090 Gene

Relevant External Links for MIR5090

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5090

No disorders were found for MIR5090 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5090 Gene

Publications for MIR5090 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N. … Zhou G. (J. Radiat. Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5090 Gene

Sources for MIR5090 Gene

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