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Aliases for MIR509-1 Gene

Subcategory (RNA class) for MIR509-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR509-1 Gene

  • MicroRNA 509-1 2 3
  • MicroRNA 509 2 3
  • Hsa-Mir-509-1 3
  • Hsa-Mir-509 3
  • MIRN509-1 3
  • MIRN509 3

External Ids for MIR509-1 Gene

Previous Symbols for MIR509-1 Gene

  • MIRN509
  • MIRN509-1

Summaries for MIR509-1 Gene

Entrez Gene Summary for MIR509-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR509-1 Gene

MIR509-1 (MicroRNA 509-1) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR509-1 Gene

Genomics for MIR509-1 Gene

Genomic Location for MIR509-1 Gene

Start:
147,260,532 bp from pter
End:
147,260,625 bp from pter
Size:
94 bases
Orientation:
Minus strand

Genomic View for MIR509-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR509-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR509-1 Gene

No data available for Regulatory Elements for MIR509-1 Gene

Proteins for MIR509-1 Gene

Post-translational modifications for MIR509-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR509-1 Gene

Domains for MIR509-1 Gene

Gene Families for MIR509-1 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR509-1: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR509-1 Gene

Function for MIR509-1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR509-1 Gene

Localization for MIR509-1 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR509-1 Gene

Pathways for MIR509-1 Gene

SuperPathways for MIR509-1 Gene

No Data Available

Interacting Proteins for MIR509-1 Gene

Gene Ontology (GO) - Biological Process for MIR509-1 Gene

None

No data available for Pathways by source for MIR509-1 Gene

Transcripts for MIR509-1 Gene

mRNA/cDNA for MIR509-1 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR509-1 Gene

No ASD Table

Relevant External Links for MIR509-1 Gene

GeneLoc Exon Structure for
MIR509-1
ECgene alternative splicing isoforms for
MIR509-1

Expression for MIR509-1 Gene

mRNA expression in normal human tissues for MIR509-1 Gene

genes like me logo Genes that share expressions with MIR509-1: view

Orthologs for MIR509-1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR509-1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-509a-1 37
  • 98 (a)
OneToOne
Species with no ortholog for MIR509-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR509-1 Gene

ENSEMBL:
Gene Tree for MIR509-1 (if available)
TreeFam:
Gene Tree for MIR509-1 (if available)

Paralogs for MIR509-1 Gene

No data available for Paralogs for MIR509-1 Gene

Variants for MIR509-1 Gene

Sequence variations from dbSNP and Humsavar for MIR509-1 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs7060824 -- 147,262,586(+) gcatg(A/C)cctgg upstream-variant-2KB
rs55759604 -- 147,262,290(+) TTTGC(C/T)GGAGA upstream-variant-2KB
rs112473678 -- 147,262,160(+) AAGCC(C/G)CAAGC upstream-variant-2KB
rs143461608 -- 147,261,951(+) GAAAG(-/T)ATCTC upstream-variant-2KB
rs144284533 -- 147,261,945(+) AATGG(G/T)GAAAG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR509-1 Gene

Variant ID Type Subtype PubMed ID
dgv2488e1 CNV Complex 17122850
esv35128 CNV Gain 17911159
nsv521982 CNV Gain 19592680
nsv508808 CNV Insertion 20534489
esv2740575 CNV Deletion 23290073

Relevant External Links for MIR509-1 Gene

HapMap Linkage Disequilibrium report
MIR509-1

Disorders for MIR509-1 Gene

No disorders were found for MIR509-1 Gene.

No data available for UniProtKB/Swiss-Prot for MIR509-1 Gene

Publications for MIR509-1 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. Analysis of gene expression in normal and neoplastic human testis: new roles of RNA. (PMID: 17573847) Novotny G.W. … Leffers H. (Int. J. Androl. 2007) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. Tumor suppressive miR-509-5p contributes to cell migration, proliferation and antiapoptosis in renal cell carcinoma. (PMID: 23619562) Zhang W.B. … Zheng X.M. (Ir J Med Sci 2013) 3

Products for MIR509-1 Gene

Sources for MIR509-1 Gene

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