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Aliases for MIR5089 Gene

Subcategory (RNA class) for MIR5089 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5089 Gene

  • MicroRNA 5089 2 3
  • Hsa-Mir-5089 3

External Ids for MIR5089 Gene

Previous GeneCards Identifiers for MIR5089 Gene

  • GC17U901694
  • GC17P045054

Summaries for MIR5089 Gene

Entrez Gene Summary for MIR5089 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5089 Gene

MIR5089 (MicroRNA 5089) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5089 Gene

Genomics for MIR5089 Gene

Genomic Location for MIR5089 Gene

Start:
46,973,017 bp from pter
End:
46,973,100 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR5089 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR5089 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5089 Gene

No data available for Regulatory Elements for MIR5089 Gene

Proteins for MIR5089 Gene

Post-translational modifications for MIR5089 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5089 Gene

Domains for MIR5089 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5089 Gene

Function for MIR5089 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR5089 Gene

Localization for MIR5089 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5089 Gene

Pathways for MIR5089 Gene

SuperPathways for MIR5089 Gene

No Data Available

Interacting Proteins for MIR5089 Gene

Gene Ontology (GO) - Biological Process for MIR5089 Gene

None

No data available for Pathways by source for MIR5089 Gene

Transcripts for MIR5089 Gene

mRNA/cDNA for MIR5089 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5089 Gene

No ASD Table

Relevant External Links for MIR5089 Gene

GeneLoc Exon Structure for
MIR5089
ECgene alternative splicing isoforms for
MIR5089

Expression for MIR5089 Gene

mRNA expression in normal human tissues for MIR5089 Gene

genes like me logo Genes that share expressions with MIR5089: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR5089 Gene

Orthologs for MIR5089 Gene

Evolution for MIR5089 Gene

ENSEMBL:
Gene Tree for MIR5089 (if available)
TreeFam:
Gene Tree for MIR5089 (if available)

No data available for Orthologs for MIR5089 Gene

Paralogs for MIR5089 Gene

No data available for Paralogs for MIR5089 Gene

Variants for MIR5089 Gene

Sequence variations from dbSNP and Humsavar for MIR5089 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs3863498 -- 46,971,733(+) CACCC(C/G)GACCT upstream-variant-2KB
rs9893406 -- 46,973,389(+) AACTC(C/G)TGGGC downstream-variant-500B
rs9901977 -- 46,971,198(+) CAGGC(A/T)TGGTG upstream-variant-2KB
rs11079746 -- 46,973,167(+) TGGAA(C/T)GCCGG downstream-variant-500B
rs11439236 -- 46,972,096(+) ATGTT(-/C)CTATA upstream-variant-2KB

Relevant External Links for MIR5089 Gene

HapMap Linkage Disequilibrium report
MIR5089

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR5089 Gene

Disorders for MIR5089 Gene

No disorders were found for MIR5089 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR5089 Gene

Publications for MIR5089 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N. … Zhou G. (J. Radiat. Res. 2011) 3
  3. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce C.E. … Bowcock A.M. (Hum. Mol. Genet. 2011) 3

Products for MIR5089 Gene

Sources for MIR5089 Gene

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