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Aliases for MIR5089 Gene

Subcategory (RNA class) for MIR5089 Gene


Quality Score for this RNA gene is


Aliases for MIR5089 Gene

  • MicroRNA 5089 2 3 5
  • Hsa-Mir-5089 3

External Ids for MIR5089 Gene

Previous GeneCards Identifiers for MIR5089 Gene

  • GC17U901694
  • GC17P045054

Summaries for MIR5089 Gene

Entrez Gene Summary for MIR5089 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5089 Gene

MIR5089 (MicroRNA 5089) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5089 Gene

Genomics for MIR5089 Gene

Regulatory Elements for MIR5089 Gene

Enhancers for MIR5089 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F046962 0.5 Ensembl 0.4 -10.4 -10417 0.4 KLF17 YBX1 ZIC2 ZFHX2 ZNF207 FOS ZBTB20 MTA2 TRIM22 TBX21 GOSR2 LOC101927060 PIR41700 MIR5089
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5089 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5089 Gene

46,973,017 bp from pter
46,973,100 bp from pter
84 bases
Plus strand

Genomic View for MIR5089 Gene

Genes around MIR5089 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5089 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5089 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5089 Gene

Proteins for MIR5089 Gene

Post-translational modifications for MIR5089 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5089 Gene

Domains & Families for MIR5089 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5089 Gene

Function for MIR5089 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5089 Gene

Localization for MIR5089 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5089 Gene

Pathways & Interactions for MIR5089 Gene

SuperPathways for MIR5089 Gene

No Data Available

Interacting Proteins for MIR5089 Gene

Gene Ontology (GO) - Biological Process for MIR5089 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR5089 Gene

Transcripts for MIR5089 Gene

mRNA/cDNA for MIR5089 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5089 Gene

No ASD Table

Relevant External Links for MIR5089 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR5089 Gene

mRNA expression in normal human tissues for MIR5089 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5089 Gene:

genes like me logo Genes that share expression patterns with MIR5089: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5089 Gene

Orthologs for MIR5089 Gene

Evolution for MIR5089 Gene

Gene Tree for MIR5089 (if available)
Gene Tree for MIR5089 (if available)

No data available for Orthologs for MIR5089 Gene

Paralogs for MIR5089 Gene

No data available for Paralogs for MIR5089 Gene

Variants for MIR5089 Gene

Sequence variations from dbSNP and Humsavar for MIR5089 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs11079746 -- 46,973,167(+) TGGAA(C/T)GCCGG intron-variant, downstream-variant-500B
rs112216108 -- 46,972,096(+) TATGT(C/T)CTATA intron-variant, upstream-variant-2KB
rs112661444 -- 46,973,128(+) GCAAC(A/C)CACAT intron-variant, downstream-variant-500B
rs11439236 -- 46,972,096(+) ATGTT(-/C)CTATA intron-variant, upstream-variant-2KB
rs114915286 -- 46,971,663(+) GATGA(A/C)GAAAC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5089 Gene

Variant ID Type Subtype PubMed ID
dgv41n68 CNV loss 17160897
esv2656635 CNV deletion 23128226
esv2758692 CNV gain+loss 17122850
nsv1146669 OTHER inversion 26484159

Relevant External Links for MIR5089 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5089 Gene

Disorders for MIR5089 Gene

Relevant External Links for MIR5089

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR5089 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5089 Gene

Publications for MIR5089 Gene

  1. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N. … Zhou G. (J. Radiat. Res. 2011) 3 64
  2. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. (PMID: 21807764) Joyce C.E. … Bowcock A.M. (Hum. Mol. Genet. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5089 Gene

Sources for MIR5089 Gene

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