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Aliases for MIR5088 Gene

Subcategory (RNA class) for MIR5088 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5088 Gene

  • MicroRNA 5088 2 3 5
  • Hsa-Mir-5088 3
  • Mir-5088 3

External Ids for MIR5088 Gene

Previous GeneCards Identifiers for MIR5088 Gene

  • GC19U901596
  • GC19P050187
  • GC19P050188

Summaries for MIR5088 Gene

Entrez Gene Summary for MIR5088 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5088 Gene

MIR5088 (MicroRNA 5088) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5088 Gene

Genomics for MIR5088 Gene

Regulatory Elements for MIR5088 Gene

Enhancers for MIR5088 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F049675 1.2 ENCODE 0.8 -3.8 -3841 6.3 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 PRR12 AKT1S1 NUP62 TEAD2 POLD1 PLEKHA4 SNORD35A BCL2L12 ALDH16A1 ENSG00000268157
GH19F049684 0.6 ENCODE 0.8 +2.4 2442 0.1 HDGF CTCF POLR2A SMC3 ZBTB7A SUPT5H GC19P049687 GC19P049689 MIR5088 PIR47705
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5088 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5088 Gene

Chromosome:
19
Start:
49,682,117 bp from pter
End:
49,682,195 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR5088 Gene

Genes around MIR5088 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5088 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5088 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5088 Gene

Proteins for MIR5088 Gene

Post-translational modifications for MIR5088 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5088 Gene

Domains & Families for MIR5088 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5088 Gene

Function for MIR5088 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5088 Gene

Localization for MIR5088 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5088 Gene

Pathways & Interactions for MIR5088 Gene

SuperPathways for MIR5088 Gene

No Data Available

Interacting Proteins for MIR5088 Gene

Gene Ontology (GO) - Biological Process for MIR5088 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5088 Gene

Transcripts for MIR5088 Gene

mRNA/cDNA for MIR5088 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5088 Gene

No ASD Table

Relevant External Links for MIR5088 Gene

GeneLoc Exon Structure for
MIR5088
ECgene alternative splicing isoforms for
MIR5088

Expression for MIR5088 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR5088 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5088 Gene:

MIR5088
genes like me logo Genes that share expression patterns with MIR5088: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5088 Gene

Orthologs for MIR5088 Gene

Evolution for MIR5088 Gene

ENSEMBL:
Gene Tree for MIR5088 (if available)
TreeFam:
Gene Tree for MIR5088 (if available)

No data available for Orthologs for MIR5088 Gene

Paralogs for MIR5088 Gene

No data available for Paralogs for MIR5088 Gene

Variants for MIR5088 Gene

Sequence variations from dbSNP and Humsavar for MIR5088 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs111301567 -- 49,681,389(+) AGGTA(A/G)CAGTG intron-variant, upstream-variant-2KB
rs111983858 -- 49,680,624(+) CTTAG(A/C/G/T)GGGGC intron-variant, upstream-variant-2KB
rs112553988 -- 49,681,296(+) CTCCG(A/G)CTTTG intron-variant, upstream-variant-2KB
rs1128424 -- 49,682,200(+) GATCG(A/T)GTGTT nc-transcript-variant, downstream-variant-500B, reference, missense
rs113823612 -- 49,682,259(+) ACCAC(C/G)GTGAG nc-transcript-variant, downstream-variant-500B, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR5088 Gene

Variant ID Type Subtype PubMed ID
nsv1160655 CNV deletion 26073780
nsv469715 CNV gain+loss 16826518
nsv470150 CNV gain 18288195
nsv817854 CNV gain 17921354
nsv833864 CNV gain 17160897
nsv833865 CNV gain+loss 17160897
nsv953600 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Relevant External Links for MIR5088 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5088

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5088 Gene

Disorders for MIR5088 Gene

Relevant External Links for MIR5088

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5088

No disorders were found for MIR5088 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5088 Gene

Publications for MIR5088 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E. … Lai E.C. (Genome Res. 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N. … Zhou G. (J. Radiat. Res. 2011) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5088 Gene

Sources for MIR5088 Gene

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