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Aliases for MIR5088 Gene

Subcategory (RNA class) for MIR5088 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5088 Gene

  • MicroRNA 5088 2 3 5
  • Hsa-Mir-5088 3
  • Mir-5088 3

External Ids for MIR5088 Gene

Previous GeneCards Identifiers for MIR5088 Gene

  • GC19U901596
  • GC19P050187
  • GC19P050188

Summaries for MIR5088 Gene

Entrez Gene Summary for MIR5088 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5088 Gene

MIR5088 (MicroRNA 5088) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5088 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5088 Gene

Genomics for MIR5088 Gene

GeneHancer (GH) Regulatory Elements for MIR5088 Gene

Promoters and enhancers for MIR5088 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I049675 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 0.8 -3.8 -3840 6.3 CLOCK DMAP1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC SSRP1 ZNF610 PRMT1 NUP62 POLD1 IRF3 PRR12 ENSG00000268047 SNORD35A PTOV1-AS2 ALDH16A1 SNORD35B
GH19I049684 Enhancer 0.6 ENCODE 0.8 +2.4 2442 0.1 HDGF CTCF SMAD5 ZNF621 POLR2A SMC3 ZNF143 ZNF444 SUPT5H GC19P049687 GC19P049689 MIR5088 PIR47705 PRMT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR5088 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR5088 Gene

Genomic Locations for MIR5088 Gene
chr19:49,682,117-49,682,195
(GRCh38/hg38)
Size:
79 bases
Orientation:
Plus strand
chr19:50,185,328-50,185,411
(GRCh37/hg19)

Genomic View for MIR5088 Gene

Genes around MIR5088 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5088 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5088 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5088 Gene

Proteins for MIR5088 Gene

Post-translational modifications for MIR5088 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5088 Gene

Domains & Families for MIR5088 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5088 Gene

Function for MIR5088 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5088 Gene

Localization for MIR5088 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5088 Gene

Pathways & Interactions for MIR5088 Gene

SuperPathways for MIR5088 Gene

No Data Available

Interacting Proteins for MIR5088 Gene

Gene Ontology (GO) - Biological Process for MIR5088 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5088 Gene

Drugs & Compounds for MIR5088 Gene

No Compound Related Data Available

Transcripts for MIR5088 Gene

mRNA/cDNA for MIR5088 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5088 Gene

No ASD Table

Relevant External Links for MIR5088 Gene

GeneLoc Exon Structure for
MIR5088
ECgene alternative splicing isoforms for
MIR5088

Expression for MIR5088 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5088 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5088 Gene:

MIR5088
genes like me logo Genes that share expression patterns with MIR5088: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5088 Gene

Orthologs for MIR5088 Gene

Evolution for MIR5088 Gene

ENSEMBL:
Gene Tree for MIR5088 (if available)
TreeFam:
Gene Tree for MIR5088 (if available)

No data available for Orthologs for MIR5088 Gene

Paralogs for MIR5088 Gene

No data available for Paralogs for MIR5088 Gene

Variants for MIR5088 Gene

Sequence variations from dbSNP and Humsavar for MIR5088 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1002501118 -- 49,681,512(+) T/TT upstream_transcript_variant
rs1002603512 -- 49,681,760(+) T/A upstream_transcript_variant
rs1002911967 -- 49,680,961(+) A/G upstream_transcript_variant
rs1003132869 -- 49,680,763(+) A/G upstream_transcript_variant
rs1004151275 -- 49,681,453(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR5088 Gene

Variant ID Type Subtype PubMed ID
nsv1160655 CNV deletion 26073780
nsv469715 CNV gain+loss 16826518
nsv470150 CNV gain 18288195
nsv817854 CNV gain 17921354
nsv833864 CNV gain 17160897
nsv833865 CNV gain+loss 17160897
nsv953600 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Additional Variant Information for MIR5088 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5088

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5088 Gene

Disorders for MIR5088 Gene

Additional Disease Information for MIR5088

No disorders were found for MIR5088 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5088 Gene

Publications for MIR5088 Gene

  1. Discovery of hundreds of mirtrons in mouse and human small RNA data. (PMID: 22955976) Ladewig E … Lai EC (Genome research 2012) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N … Zhou G (Journal of radiation research 2011) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR5088 Gene

Sources for MIR5088 Gene

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