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Aliases for MIR5087 Gene

Subcategory (RNA class) for MIR5087 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR5087 Gene

  • MicroRNA 5087 2 3 5
  • Hsa-Mir-5087 3

External Ids for MIR5087 Gene

Previous GeneCards Identifiers for MIR5087 Gene

  • GC01U903313

Summaries for MIR5087 Gene

Entrez Gene Summary for MIR5087 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5087 Gene

MIR5087 (MicroRNA 5087) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5087 Gene

Genomics for MIR5087 Gene

Regulatory Elements for MIR5087 Gene

Enhancers for MIR5087 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR5087 on UCSC Golden Path with GeneCards custom track

Promoters for MIR5087 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for MIR5087 Gene

Chromosome:
1
Start:
148,334,479 bp from pter
End:
148,334,554 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR5087 Gene

Genes around MIR5087 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5087 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5087 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5087 Gene

ORGUL Member Location for MIR5087 Gene

ORGUL Member Location for MIR5087 gene

Proteins for MIR5087 Gene

Post-translational modifications for MIR5087 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5087 Gene

Domains & Families for MIR5087 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5087 Gene

Function for MIR5087 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5087 Gene

Localization for MIR5087 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5087 Gene

Pathways & Interactions for MIR5087 Gene

SuperPathways for MIR5087 Gene

No Data Available

Interacting Proteins for MIR5087 Gene

Gene Ontology (GO) - Biological Process for MIR5087 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5087 Gene

Drugs & Compounds for MIR5087 Gene

No Compound Related Data Available

Transcripts for MIR5087 Gene

mRNA/cDNA for MIR5087 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5087 Gene

No ASD Table

Relevant External Links for MIR5087 Gene

GeneLoc Exon Structure for
MIR5087
ECgene alternative splicing isoforms for
MIR5087

Expression for MIR5087 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5087 Gene:

MIR5087
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5087 Gene

Orthologs for MIR5087 Gene

Evolution for MIR5087 Gene

ENSEMBL:
Gene Tree for MIR5087 (if available)
TreeFam:
Gene Tree for MIR5087 (if available)

No data available for Orthologs for MIR5087 Gene

Paralogs for MIR5087 Gene

No data available for Paralogs for MIR5087 Gene

Variants for MIR5087 Gene

Sequence variations from dbSNP and Humsavar for MIR5087 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs508233 -- 148,335,840(+) CACTC(A/G)GGCAT upstream-variant-2KB
rs481176 -- 148,335,153(+) TCCAA(A/G)GAAGC upstream-variant-2KB
rs537191 -- 148,334,756(+) CGATG(C/T)CAGGT upstream-variant-2KB
rs539114 -- 148,334,986(+) TACAT(A/T)GAAGT upstream-variant-2KB
rs1814656 -- 148,335,881(+) CTTCT(C/G)TAGAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5087 Gene

Variant ID Type Subtype PubMed ID
dgv327n100 CNV gain 25217958
dgv336n100 CNV gain+loss 25217958
dgv535n54 CNV gain 21841781
dgv66e199 CNV deletion 23128226
esv2761299 CNV gain+loss 21179565
esv3572675 CNV gain 25503493
esv3894134 CNV loss 25118596
nsv1000564 CNV gain 25217958
nsv1003688 CNV gain 25217958
nsv1005055 CNV loss 25217958
nsv1009417 CNV gain 25217958
nsv1132304 CNV duplication 24896259
nsv509457 CNV insertion 20534489
nsv510962 OTHER complex 20534489
nsv510984 OTHER inversion 20534489
nsv547679 CNV loss 21841781
nsv547682 CNV loss 21841781
nsv831448 CNV loss 17160897
nsv946326 CNV duplication 23825009

Relevant External Links for MIR5087 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5087

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5087 Gene

Disorders for MIR5087 Gene

Relevant External Links for MIR5087

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5087

No disorders were found for MIR5087 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5087 Gene

Publications for MIR5087 Gene

  1. Detection of novel human MiRNAs responding to X-ray irradiation. (PMID: 21785231) Ding N. … Zhou G. (J. Radiat. Res. 2011) 3 65
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 65

Products for MIR5087 Gene

Sources for MIR5087 Gene

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