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Aliases for MIR502 Gene

Subcategory (RNA class) for MIR502 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR502 Gene

  • MicroRNA 502 2 3 5
  • Hsa-Mir-502 3
  • Mir-502 3
  • MIRN502 3

External Ids for MIR502 Gene

ORGUL Members for MIR502 Gene

Previous HGNC Symbols for MIR502 Gene

  • MIRN502

Previous GeneCards Identifiers for MIR502 Gene

  • GC0XP049669
  • GC0XP049779

Summaries for MIR502 Gene

Entrez Gene Summary for MIR502 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR502 Gene

MIR502 (MicroRNA 502) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR502 Gene

Genomics for MIR502 Gene

Genomic Location for MIR502 Gene

Chromosome:
X
Start:
50,014,598 bp from pter
End:
50,014,683 bp from pter
Size:
86 bases
Orientation:
Plus strand

Genomic View for MIR502 Gene

Genes around MIR502 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR502 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR502 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR502 Gene

No data available for Regulatory Elements for MIR502 Gene

Proteins for MIR502 Gene

Post-translational modifications for MIR502 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR502 Gene

Domains & Families for MIR502 Gene

Gene Families for MIR502 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR502: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR502 Gene

Function for MIR502 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR502 Gene

Localization for MIR502 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR502 Gene

Pathways & Interactions for MIR502 Gene

SuperPathways for MIR502 Gene

No Data Available

Interacting Proteins for MIR502 Gene

Gene Ontology (GO) - Biological Process for MIR502 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR502 Gene

Drugs & Compounds for MIR502 Gene

No Compound Related Data Available

Transcripts for MIR502 Gene

mRNA/cDNA for MIR502 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR502 Gene

No ASD Table

Relevant External Links for MIR502 Gene

GeneLoc Exon Structure for
MIR502
ECgene alternative splicing isoforms for
MIR502

Expression for MIR502 Gene

mRNA expression in normal human tissues for MIR502 Gene

genes like me logo Genes that share expression patterns with MIR502: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR502 Gene

Orthologs for MIR502 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR502 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-502a-1 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-502 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir500 36
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-502 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR502:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR502 Gene

ENSEMBL:
Gene Tree for MIR502 (if available)
TreeFam:
Gene Tree for MIR502 (if available)

Paralogs for MIR502 Gene

No data available for Paralogs for MIR502 Gene

Variants for MIR502 Gene

Relevant External Links for MIR502 Gene

HapMap Linkage Disequilibrium report
MIR502
Human Gene Mutation Database (HGMD)
MIR502

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR502 Gene

Disorders for MIR502 Gene

Relevant External Links for MIR502

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR502

No disorders were found for MIR502 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR502 Gene

Publications for MIR502 Gene

  1. Suppressive role of miR-502-5p in breast cancer via downregulation of TRAF2. (PMID: 24677135) Sun L.L. … Mi X.Y. (Oncol. Rep. 2014) 3
  2. Association of functional polymorphism at the miR-502-binding site in the 3' untranslated region of the SETD8 gene with risk of childhood acute lymphoblastic leukemia, a preliminary report. (PMID: 25048968) Hashemi M. … Taheri M. (Tumour Biol. 2014) 3
  3. Prognostic value of microRNA 502 binding site SNP in the 3'-untranslated region of the SET8 gene in patients with non-Hodgkin's lymphoma. (PMID: 25343552) Diao L. … Guo Z. (Tumori 2014) 3
  4. Inhibition of autophagy and tumor growth in colon cancer by miR-502. (PMID: 22580605) Zhai H. … Ju J. (Oncogene 2013) 3
  5. Association of miR-502-binding site single nucleotide polymorphism in the 3'-untranslated region of SET8 and TP53 codon 72 polymorphism with non-small cell lung cancer in Chinese population. (PMID: 24374662) Yang S. … Tang J. (Acta Biochim. Biophys. Sin. (Shanghai) 2013) 3

Products for MIR502 Gene

Sources for MIR502 Gene

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