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Aliases for MIR500B Gene

Subcategory (RNA class) for MIR500B Gene


Quality Score for this RNA gene is


Aliases for MIR500B Gene

  • MicroRNA 500b 2 3
  • Hsa-Mir-500b 3

External Ids for MIR500B Gene

ORGUL Members for MIR500B Gene

Previous GeneCards Identifiers for MIR500B Gene

  • GC0XU901645
  • GC0XP047245
  • GC0XP049785
  • GC0XP049788
  • GC0XP049791
  • GC0XP049794
  • GC0XP049798
  • GC0XP049812
  • GC0XP049838

Summaries for MIR500B Gene

Entrez Gene Summary for MIR500B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR500B Gene

MIR500B (MicroRNA 500b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR500B Gene

Genomics for MIR500B Gene

Genomic Location for MIR500B Gene

50,010,671 bp from pter
50,010,750 bp from pter
80 bases
Plus strand

Genomic View for MIR500B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR500B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR500B Gene

No data available for Regulatory Elements for MIR500B Gene

Proteins for MIR500B Gene

Post-translational modifications for MIR500B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR500B Gene

Domains for MIR500B Gene

Gene Families for MIR500B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR500B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR500B Gene

Function for MIR500B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR500B Gene

Localization for MIR500B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR500B Gene

Pathways for MIR500B Gene

SuperPathways for MIR500B Gene

No Data Available

Interacting Proteins for MIR500B Gene

Gene Ontology (GO) - Biological Process for MIR500B Gene


No data available for Pathways by source for MIR500B Gene

Transcripts for MIR500B Gene

mRNA/cDNA for MIR500B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR500B Gene

No ASD Table

Relevant External Links for MIR500B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR500B Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR500B Gene

Orthologs for MIR500B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR500B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-500 36
  • 86 (a)
(Canis familiaris)
Mammalia -- 36
  • 88 (a)
(Pan troglodytes)
Mammalia ptr-mir-500-2 36
  • 100 (a)
Species with no ortholog for MIR500B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR500B Gene

Gene Tree for MIR500B (if available)
Gene Tree for MIR500B (if available)

Paralogs for MIR500B Gene

No data available for Paralogs for MIR500B Gene

Variants for MIR500B Gene

Relevant External Links for MIR500B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR500B Gene

Disorders for MIR500B Gene

No disorders were found for MIR500B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR500B Gene

Publications for MIR500B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3
  3. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3

Products for MIR500B Gene

Sources for MIR500B Gene

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