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Aliases for MIR500A Gene

Subcategory (RNA class) for MIR500A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR500A Gene

  • MicroRNA 500a 2 3
  • MicroRNA 500 2 3
  • Hsa-Mir-500a 3
  • Hsa-Mir-500 3
  • MIRN500 3
  • MIR500 3

External Ids for MIR500A Gene

ORGUL Members for MIR500A Gene

Previous Symbols for MIR500A Gene

  • MIRN500
  • MIR500

Summaries for MIR500A Gene

Entrez Gene Summary for MIR500A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR500A Gene

MIR500A (MicroRNA 500a) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR500A Gene

Genomics for MIR500A Gene

Genomic Location for MIR500A Gene

Start:
50,008,431 bp from pter
End:
50,008,514 bp from pter
Size:
84 bases
Orientation:
Plus strand

Genomic View for MIR500A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR500A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR500A Gene

No data available for Regulatory Elements for MIR500A Gene

Proteins for MIR500A Gene

Post-translational modifications for MIR500A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR500A Gene

Domains for MIR500A Gene

Gene Families for MIR500A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR500A: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR500A Gene

Function for MIR500A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR500A Gene

Localization for MIR500A Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR500A Gene

Pathways for MIR500A Gene

SuperPathways for MIR500A Gene

No Data Available

Interacting Proteins for MIR500A Gene

Gene Ontology (GO) - Biological Process for MIR500A Gene

None

No data available for Pathways by source for MIR500A Gene

Transcripts for MIR500A Gene

mRNA/cDNA for MIR500A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR500A Gene

No ASD Table

Relevant External Links for MIR500A Gene

GeneLoc Exon Structure for
MIR500A
ECgene alternative splicing isoforms for
MIR500A

Expression for MIR500A Gene

mRNA expression in normal human tissues for MIR500A Gene

genes like me logo Genes that share expressions with MIR500A: view

Orthologs for MIR500A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR500A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-500-1 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-502b 37
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-500 37
  • 98 (a)
OneToOne
Species with no ortholog for MIR500A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR500A Gene

ENSEMBL:
Gene Tree for MIR500A (if available)
TreeFam:
Gene Tree for MIR500A (if available)

Paralogs for MIR500A Gene

No data available for Paralogs for MIR500A Gene

Variants for MIR500A Gene

Relevant External Links for MIR500A Gene

HapMap Linkage Disequilibrium report
MIR500A

No data available for Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR500A Gene

Disorders for MIR500A Gene

No disorders were found for MIR500A Gene.

No data available for UniProtKB/Swiss-Prot for MIR500A Gene

Publications for MIR500A Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma. (PMID: 19863192) Yamamoto Y. … Ochiya T. (Biomarkers 2009) 3

Products for MIR500A Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR500A
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR500A
    • Block miRNA regulation of MIR500A using miScript Target Protectors

    Sources for MIR500A Gene

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