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Aliases for MIR5008 Gene

Subcategory (RNA class) for MIR5008 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5008 Gene

  • MicroRNA 5008 2 3 5
  • Hsa-Mir-5008 3

External Ids for MIR5008 Gene

Previous GeneCards Identifiers for MIR5008 Gene

  • GC01U903345
  • GC01M228132

Summaries for MIR5008 Gene

Entrez Gene Summary for MIR5008 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5008 Gene

MIR5008 (MicroRNA 5008) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5008 Gene

Genomics for MIR5008 Gene

Regulatory Elements for MIR5008 Gene

Enhancers for MIR5008 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F227942 0.9 ENCODE 0.8 -4.0 -4034 6.0 HDGF PKNOX1 ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF143 FOS KLF13 C1orf145 WNT3A OBSCN IBA57 ENSG00000269934 MRPL55 MIR5008 WNT9A
GH01F227937 0.3 FANTOM5 0.8 +4.5 4505 0.1 GATA3 ARF1 MIR5008 PRSS38
GH01F227933 1 Ensembl ENCODE 0.4 +6.7 6685 2.6 ATF1 PKNOX1 INSM2 KLF17 ZEB1 ZNF391 FOS CREM ZNF280D SP3 CICP26 OBSCN C1orf145 HIST3H3 ENSG00000269890 MIR5008 PRSS38
GH01F227914 0.9 ENCODE 0.3 +27.1 27089 0.2 INSM2 KLF17 NFXL1 GLI4 ZNF2 RAD21 ZNF335 GLIS2 KLF7 EGR2 MIR5008 PRSS38
GH01F227915 0.4 ENCODE 0.3 +25.9 25869 0.2 HDGF MLX ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 CICP26 ENSG00000269890 MIR5008 PRSS38
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR5008 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5008 Gene

Chromosome:
1
Start:
227,941,590 bp from pter
End:
227,941,683 bp from pter
Size:
94 bases
Orientation:
Minus strand

Genomic View for MIR5008 Gene

Genes around MIR5008 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5008 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5008 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5008 Gene

Proteins for MIR5008 Gene

Post-translational modifications for MIR5008 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5008 Gene

Domains & Families for MIR5008 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5008 Gene

Function for MIR5008 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5008 Gene

Localization for MIR5008 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5008 Gene

Pathways & Interactions for MIR5008 Gene

SuperPathways for MIR5008 Gene

No Data Available

Interacting Proteins for MIR5008 Gene

Gene Ontology (GO) - Biological Process for MIR5008 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5008 Gene

Transcripts for MIR5008 Gene

mRNA/cDNA for MIR5008 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5008 Gene

No ASD Table

Relevant External Links for MIR5008 Gene

GeneLoc Exon Structure for
MIR5008
ECgene alternative splicing isoforms for
MIR5008

Expression for MIR5008 Gene

mRNA expression in normal human tissues for MIR5008 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5008 Gene:

MIR5008
genes like me logo Genes that share expression patterns with MIR5008: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR5008 Gene

Orthologs for MIR5008 Gene

Evolution for MIR5008 Gene

ENSEMBL:
Gene Tree for MIR5008 (if available)
TreeFam:
Gene Tree for MIR5008 (if available)

No data available for Orthologs for MIR5008 Gene

Paralogs for MIR5008 Gene

No data available for Paralogs for MIR5008 Gene

Variants for MIR5008 Gene

Sequence variations from dbSNP and Humsavar for MIR5008 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs113467877 -- 227,943,427(+) AAACA(A/G)GCAAA intron-variant, upstream-variant-2KB
rs114394244 -- 227,941,113(+) GCACT(A/G)CACTA intron-variant, downstream-variant-500B
rs142445920 -- 227,942,881(+) GATGC(C/T)GCCTT intron-variant, upstream-variant-2KB
rs143134076 -- 227,942,990(+) AGGTG(-/C)CCCCT intron-variant, upstream-variant-2KB
rs144594745 -- 227,941,929(+) TTCCC(A/G)CAGCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5008 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV gain 17666407
nsv516409 CNV loss 19592680
nsv523935 CNV loss 19592680
nsv826908 CNV gain 20364138
nsv952132 CNV deletion 24416366

Relevant External Links for MIR5008 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5008

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5008 Gene

Disorders for MIR5008 Gene

Relevant External Links for MIR5008

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5008

No disorders were found for MIR5008 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5008 Gene

Publications for MIR5008 Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen T.B. … Bramsen J.B. (RNA Biol 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5008 Gene

Sources for MIR5008 Gene

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