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Aliases for MIR5008 Gene

Subcategory (RNA class) for MIR5008 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5008 Gene

  • MicroRNA 5008 2 3 5
  • Hsa-Mir-5008 3

External Ids for MIR5008 Gene

Previous GeneCards Identifiers for MIR5008 Gene

  • GC01U903345
  • GC01M228132

Summaries for MIR5008 Gene

Entrez Gene Summary for MIR5008 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5008 Gene

MIR5008 (MicroRNA 5008) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR5008 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5008 Gene

Genomics for MIR5008 Gene

Regulatory Elements for MIR5008 Gene

Enhancers for MIR5008 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H227942 1.3 ENCODE dbSUPER 0.7 -4.0 -4034 5 ARNT SIN3A ZNF2 ZBTB7B ZNF121 GLIS2 ELK1 ZNF143 FOS KLF7 OBSCN-AS1 WNT3A OBSCN IBA57 ENSG00000269934 MRPL55 MIR5008 WNT9A
GH01H227933 1.4 Ensembl ENCODE dbSUPER 0.4 +6.7 6685 2 ZNF473 INSM2 KLF17 ZEB1 ZNF391 FOS SP3 ZNF280D ZNF174 TSHZ1 ZNF678 CICP26 OBSCN OBSCN-AS1 C1orf35 JMJD4 CDC42BPA HIST3H3 MIR5008 PRSS38
GH01H227937 0.5 FANTOM5 0.7 +4.5 4505 0 GATA3 TARDBP DPF2 ARF1 MIR5008 PRSS38
GH01H227885 1.4 FANTOM5 Ensembl ENCODE 0.2 +54.3 54321 4 PKNOX1 YY1 TCF12 GATA2 SCRT2 FOS EGR2 REST HDAC8 ZNF592 WNT9A MIR5008 PRSS38
GH01H227909 0.9 FANTOM5 ENCODE 0.3 +31.0 30977 1 MAZ SP3 KLF1 ZNF280D KLF17 NFXL1 ZFHX2 ZNF341 WT1 EGR2 WNT3A MIR5008 PRSS38
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5008 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5008 Gene

Chromosome:
1
Start:
227,941,590 bp from pter
End:
227,941,683 bp from pter
Size:
94 bases
Orientation:
Minus strand

Genomic View for MIR5008 Gene

Genes around MIR5008 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5008 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5008 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5008 Gene

Proteins for MIR5008 Gene

Post-translational modifications for MIR5008 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5008 Gene

Domains & Families for MIR5008 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5008 Gene

Function for MIR5008 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5008
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5008 Gene

Localization for MIR5008 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR5008 Gene

Pathways & Interactions for MIR5008 Gene

SuperPathways for MIR5008 Gene

No Data Available

Interacting Proteins for MIR5008 Gene

Gene Ontology (GO) - Biological Process for MIR5008 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5008 Gene

Drugs & Compounds for MIR5008 Gene

No Compound Related Data Available

Transcripts for MIR5008 Gene

mRNA/cDNA for MIR5008 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR5008
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5008 Gene

No ASD Table

Relevant External Links for MIR5008 Gene

GeneLoc Exon Structure for
MIR5008
ECgene alternative splicing isoforms for
MIR5008

Expression for MIR5008 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5008 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5008 Gene:

MIR5008
genes like me logo Genes that share expression patterns with MIR5008: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5008 Gene

Orthologs for MIR5008 Gene

Evolution for MIR5008 Gene

ENSEMBL:
Gene Tree for MIR5008 (if available)
TreeFam:
Gene Tree for MIR5008 (if available)

No data available for Orthologs for MIR5008 Gene

Paralogs for MIR5008 Gene

No data available for Paralogs for MIR5008 Gene

Variants for MIR5008 Gene

Sequence variations from dbSNP and Humsavar for MIR5008 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1001728115 -- 227,943,179(+) AGCCT(C/G)CTCTT intron-variant, upstream-variant-2KB
rs1002532055 -- 227,942,268(+) CACAC(A/G)CCCTC intron-variant, upstream-variant-2KB
rs1004036457 -- 227,941,976(+) AGGGT(C/T)CAGAG intron-variant, upstream-variant-2KB
rs1005105121 -- 227,943,302(+) GCAGG(G/T)GTAAG intron-variant, upstream-variant-2KB
rs1008063633 -- 227,942,564(+) CCTGG(-/C)CCCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5008 Gene

Variant ID Type Subtype PubMed ID
esv32853 CNV gain 17666407
nsv516409 CNV loss 19592680
nsv523935 CNV loss 19592680
nsv826908 CNV gain 20364138
nsv952132 CNV deletion 24416366

Relevant External Links for MIR5008 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5008

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5008 Gene

Disorders for MIR5008 Gene

Relevant External Links for MIR5008

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5008

No disorders were found for MIR5008 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5008 Gene

Publications for MIR5008 Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen TB … Bramsen JB (RNA biology 2011) 3 60
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR5008 Gene

Sources for MIR5008 Gene

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