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Aliases for MIR5003 Gene

Subcategory (RNA class) for MIR5003 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR5003 Gene

  • MicroRNA 5003 2 3 5
  • Hsa-Mir-5003 3

External Ids for MIR5003 Gene

Previous GeneCards Identifiers for MIR5003 Gene

  • GC05U901615
  • GC05P172094

Summaries for MIR5003 Gene

Entrez Gene Summary for MIR5003 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR5003 Gene

MIR5003 (MicroRNA 5003) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR5003 Gene

Genomics for MIR5003 Gene

Regulatory Elements for MIR5003 Gene

Enhancers for MIR5003 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G172657 1.5 Ensembl ENCODE dbSUPER 0.7 -0.3 -274 8.6 PKNOX1 FOXA2 ZFP64 ARID4B SIN3A DMAP1 ZNF48 ZBTB7B YY1 GLIS2 NEURL1B SH3PXD2B LOC100268168 ENSG00000254295 RPL26L1 GC05P172658 MIR5003
GH05G172666 0.5 dbSUPER 0.7 +4.6 4612 0.8 CTCF ZMYM3 REST CEBPG RAD21 MIR5003 GC05M172673
GH05G172669 0.7 ENCODE dbSUPER 0.4 +6.9 6928 0.2 ZFHX2 EP300 EGR2 GC05M172673 MIR5003
GH05G172668 0.6 Ensembl dbSUPER 0.4 +6.4 6436 0.4 CTCF GC05M172673 MIR5003
GH05G172667 0.4 dbSUPER 0.4 +5.8 5750 0.6 ZNF623 GC05M172673 MIR5003
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR5003 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR5003 Gene

Chromosome:
5
Start:
172,662,165 bp from pter
End:
172,662,263 bp from pter
Size:
99 bases
Orientation:
Plus strand

Genomic View for MIR5003 Gene

Genes around MIR5003 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR5003 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR5003 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR5003 Gene

Proteins for MIR5003 Gene

Post-translational modifications for MIR5003 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR5003 Gene

Domains & Families for MIR5003 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR5003 Gene

Function for MIR5003 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR5003 Gene

Localization for MIR5003 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR5003 Gene

Pathways & Interactions for MIR5003 Gene

SuperPathways for MIR5003 Gene

No Data Available

Interacting Proteins for MIR5003 Gene

Gene Ontology (GO) - Biological Process for MIR5003 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR5003 Gene

Drugs & Compounds for MIR5003 Gene

No Compound Related Data Available

Transcripts for MIR5003 Gene

mRNA/cDNA for MIR5003 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR5003 Gene

No ASD Table

Relevant External Links for MIR5003 Gene

GeneLoc Exon Structure for
MIR5003
ECgene alternative splicing isoforms for
MIR5003

Expression for MIR5003 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR5003 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR5003 Gene:

MIR5003
genes like me logo Genes that share expression patterns with MIR5003: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR5003 Gene

Orthologs for MIR5003 Gene

Evolution for MIR5003 Gene

ENSEMBL:
Gene Tree for MIR5003 (if available)
TreeFam:
Gene Tree for MIR5003 (if available)

No data available for Orthologs for MIR5003 Gene

Paralogs for MIR5003 Gene

No data available for Paralogs for MIR5003 Gene

Variants for MIR5003 Gene

Sequence variations from dbSNP and Humsavar for MIR5003 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000133670 -- 172,662,165(+) GTCTG(A/T)TGAGT intron-variant, nc-transcript-variant
rs1001679769 -- 172,660,260(+) TCAGC(A/T)TGGGA intron-variant, upstream-variant-2KB
rs1003247999 -- 172,660,967(+) CCCAC(C/G)AATGG intron-variant, upstream-variant-2KB
rs1003267922 -- 172,660,770(+) AAGTA(A/G)CTGGG intron-variant, upstream-variant-2KB
rs1003340809 -- 172,662,132(+) TAATG(A/G)GCACC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR5003 Gene

Variant ID Type Subtype PubMed ID
dgv10173n54 CNV gain 21841781
dgv208e55 CNV gain 17911159
dgv5831n100 CNV gain 25217958
dgv729n27 CNV gain 19166990
esv2759393 CNV gain 17122850
esv2763518 CNV gain 21179565
esv34432 CNV gain 17911159
esv3607596 CNV gain 21293372
nsv1032497 CNV gain 25217958
nsv441974 CNV gain 18776908
nsv523045 CNV gain 19592680
nsv600287 CNV loss 21841781
nsv600289 CNV loss 21841781

Relevant External Links for MIR5003 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR5003

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR5003 Gene

Disorders for MIR5003 Gene

Relevant External Links for MIR5003

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR5003

No disorders were found for MIR5003 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR5003 Gene

Publications for MIR5003 Gene

  1. Enhancing miRNA annotation confidence in miRBase by continuous cross dataset analysis. (PMID: 21558790) Hansen T.B. … Bramsen J.B. (RNA Biol 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR5003 Gene

Sources for MIR5003 Gene

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