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Aliases for MIR499B Gene

Subcategory (RNA class) for MIR499B Gene

miRNA

Quality Score for this RNA gene is

7

Aliases for MIR499B Gene

  • MicroRNA 499b 2 3
  • MicroRNA 499a 2 3
  • Hsa-Mir-499a 3
  • Hsa-Mir-499b 3
  • MIR499A 3

External Ids for MIR499B Gene

Previous HGNC Symbols for MIR499B Gene

  • MIR499A

Previous GeneCards Identifiers for MIR499B Gene

  • GC20U900708
  • GC20M033582

Summaries for MIR499B Gene

Entrez Gene Summary for MIR499B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR499B Gene

MIR499B (MicroRNA 499b) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR499B Gene

Genomics for MIR499B Gene

Genomic Location for MIR499B Gene

Start:
34,990,400 bp from pter
End:
34,990,472 bp from pter
Size:
73 bases
Orientation:
Minus strand

Genomic View for MIR499B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR499B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR499B Gene

ORGUL Member Location for MIR499B Gene

ORGUL Member Location for MIR499B gene

No data available for Regulatory Elements for MIR499B Gene

Proteins for MIR499B Gene

Post-translational modifications for MIR499B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR499B Gene

Domains for MIR499B Gene

Gene Families for MIR499B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR499B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR499B Gene

Function for MIR499B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR499B Gene

Localization for MIR499B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR499B Gene

Pathways for MIR499B Gene

SuperPathways for MIR499B Gene

No Data Available

Interacting Proteins for MIR499B Gene

Gene Ontology (GO) - Biological Process for MIR499B Gene

None

No data available for Pathways by source for MIR499B Gene

Transcripts for MIR499B Gene

Alternative Splicing Database (ASD) splice patterns (SP) for MIR499B Gene

No ASD Table

Relevant External Links for MIR499B Gene

GeneLoc Exon Structure for
MIR499B
ECgene alternative splicing isoforms for
MIR499B

No data available for mRNA/cDNA for MIR499B Gene

Expression for MIR499B Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR499B Gene

Orthologs for MIR499B Gene

No data available for Orthologs and Evolution for MIR499B Gene

Paralogs for MIR499B Gene

No data available for Paralogs for MIR499B Gene

Variants for MIR499B Gene

Relevant External Links for MIR499B Gene

HapMap Linkage Disequilibrium report
MIR499B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR499B Gene

Disorders for MIR499B Gene

No disorders were found for MIR499B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR499B Gene

Publications for MIR499B Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR499B Gene

Sources for MIR499B Gene

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