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Aliases for MIR496 Gene

Subcategory (RNA class) for MIR496 Gene


Quality Score for this RNA gene is


Aliases for MIR496 Gene

  • MicroRNA 496 2 3
  • Hsa-Mir-496 3
  • Mir-496 3
  • MIRN496 3

External Ids for MIR496 Gene

ORGUL Members for MIR496 Gene

Previous HGNC Symbols for MIR496 Gene

  • MIRN496

Previous GeneCards Identifiers for MIR496 Gene

  • GC14P100837
  • GC14P100927
  • GC14P101528
  • GC14P101557
  • GC14P101591
  • GC14P101630
  • GC14P101658
  • GC14P101692
  • GC14P101730
  • GC14P101770
  • GC14P101828
  • GC14P101968
  • GC14P102165
  • GC14P101270

Summaries for MIR496 Gene

Entrez Gene Summary for MIR496 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR496 Gene

MIR496 (MicroRNA 496) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR496 include facioscapulohumeral muscular dystrophy 1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR496 Gene

Genomics for MIR496 Gene

Genomic Location for MIR496 Gene

101,060,558 bp from pter
101,060,674 bp from pter
117 bases
Plus strand

Genomic View for MIR496 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR496 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR496 Gene

No data available for Regulatory Elements for MIR496 Gene

Proteins for MIR496 Gene

Post-translational modifications for MIR496 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR496 Gene

Domains & Families for MIR496 Gene

Gene Families for MIR496 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR496: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR496 Gene

Function for MIR496 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR496 Gene

Localization for MIR496 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR496 Gene

Pathways & Interactions for MIR496 Gene

SuperPathways for MIR496 Gene

No Data Available

Interacting Proteins for MIR496 Gene

Gene Ontology (GO) - Biological Process for MIR496 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR496 Gene

Drugs & Compounds for MIR496 Gene

No Compound Related Data Available

Transcripts for MIR496 Gene

mRNA/cDNA for MIR496 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR496 Gene

No ASD Table

Relevant External Links for MIR496 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR496 Gene

mRNA expression in normal human tissues for MIR496 Gene

genes like me logo Genes that share expression patterns with MIR496: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR496 Gene

Orthologs for MIR496 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR496 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-496 36
  • 79 (a)
(Canis familiaris)
Mammalia cfa-mir-496 36
  • 97 (a)
(Mus musculus)
Mammalia Mir496 36
  • 94 (a)
(Pan troglodytes)
Mammalia ptr-mir-496 36
  • 100 (a)
Species with no ortholog for MIR496:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR496 Gene

Gene Tree for MIR496 (if available)
Gene Tree for MIR496 (if available)

Paralogs for MIR496 Gene

No data available for Paralogs for MIR496 Gene

Variants for MIR496 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR496 Gene

Variant ID Type Subtype PubMed ID
nsv509551 CNV Insertion 20534489

Relevant External Links for MIR496 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR496 Gene

Disorders for MIR496 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR496 Gene - From: DISEASES

Disorder Aliases PubMed IDs
facioscapulohumeral muscular dystrophy 1
  • facioscapulohumeral muscular dystrophy
- elite association

Relevant External Links for MIR496

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR496: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR496 Gene

Publications for MIR496 Gene

  1. Methylated DNA binding domain protein 2 (MBD2) coordinately silences gene expression through activation of the microRNA hsa-mir-496 promoter in breast cancer cell line. (PMID: 24204564) Alvarado S. … Szyf M. (PLoS ONE 2013) 67
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 67
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 67
  5. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 67

Products for MIR496 Gene

Sources for MIR496 Gene

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