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Aliases for MIR495 Gene

Subcategory (RNA class) for MIR495 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR495 Gene

  • MicroRNA 495 2 3
  • Hsa-Mir-495 3
  • MIRN495 3
  • MIR551A 6

External Ids for MIR495 Gene

ORGUL Members for MIR495 Gene

Previous HGNC Symbols for MIR495 Gene

  • MIRN495

Previous GeneCards Identifiers for MIR495 Gene

  • GC14P100821
  • GC14P100912
  • GC14P101504
  • GC14P101505
  • GC14P101569
  • GC14P101611
  • GC14P101636
  • GC14P101670
  • GC14P101711
  • GC14P101752
  • GC14P101810
  • GC14P101950
  • GC14P102141

Summaries for MIR495 Gene

Entrez Gene Summary for MIR495 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR495 Gene

MIR495 (MicroRNA 495) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR495 Gene

Genomics for MIR495 Gene

Genomic Location for MIR495 Gene

Start:
101,033,734 bp from pter
End:
101,033,841 bp from pter
Size:
108 bases
Orientation:
Plus strand

Genomic View for MIR495 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR495 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR495 Gene

No data available for Regulatory Elements for MIR495 Gene

Proteins for MIR495 Gene

Post-translational modifications for MIR495 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR495 Gene

Domains for MIR495 Gene

Gene Families for MIR495 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR495: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR495 Gene

Function for MIR495 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR495 Gene

Localization for MIR495 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR495 Gene

Pathways for MIR495 Gene

SuperPathways for MIR495 Gene

No Data Available

Interacting Proteins for MIR495 Gene

Gene Ontology (GO) - Biological Process for MIR495 Gene

None

No data available for Pathways by source for MIR495 Gene

Transcripts for MIR495 Gene

mRNA/cDNA for MIR495 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR495 Gene

No ASD Table

Relevant External Links for MIR495 Gene

GeneLoc Exon Structure for
MIR495
ECgene alternative splicing isoforms for
MIR495

Expression for MIR495 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR495 Gene

Orthologs for MIR495 Gene

Evolution for MIR495 Gene

ENSEMBL:
Gene Tree for MIR495 (if available)
TreeFam:
Gene Tree for MIR495 (if available)

No data available for Orthologs for MIR495 Gene

Paralogs for MIR495 Gene

No data available for Paralogs for MIR495 Gene

Variants for MIR495 Gene

Sequence variations from dbSNP and Humsavar for MIR495 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs2281611 -- 101,033,612(-) GCTCA(A/C)CCCAG upstream-variant-2KB
rs8004162 -- 101,033,600(+) CCCCC(A/G)CCTCC upstream-variant-2KB
rs8004285 -- 101,033,543(+) TTATC(C/T)GTGAT upstream-variant-2KB
rs8004825 -- 101,033,167(+) ACACT(G/T)AACTG upstream-variant-2KB
rs11625331 -- 101,032,700(+) acttg(G/T)ttaag upstream-variant-2KB

Relevant External Links for MIR495 Gene

HapMap Linkage Disequilibrium report
MIR495

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MIR495 Gene

Disorders for MIR495 Gene

No disorders were found for MIR495 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR495 Gene

Publications for MIR495 Gene

  1. Identification of hundreds of conserved and nonconserved human microRNAs. (PMID: 15965474) Bentwich I. … Bentwich Z. (Nat. Genet. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. (PMID: 21258409) Hwang-Verslues W.W. … Lee W.H. (Oncogene 2011) 3
  5. Deep-sequencing of endothelial cells exposed to hypoxia reveals the complexity of known and novel microRNAs. (PMID: 22282338) Voellenkle C. … Martelli F. (RNA 2012) 3

Products for MIR495 Gene

Sources for MIR495 Gene

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