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Aliases for MIR492 Gene

Subcategory (RNA class) for MIR492 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR492 Gene

  • MicroRNA 492 2 3 5
  • Hsa-Mir-492 3
  • MIRN492 3

External Ids for MIR492 Gene

ORGUL Members for MIR492 Gene

Previous HGNC Symbols for MIR492 Gene

  • MIRN492

Previous GeneCards Identifiers for MIR492 Gene

  • GC12P093753
  • GC12P095229
  • GC12P095230
  • GC12P095232
  • GC12P095234
  • GC12P095236

Summaries for MIR492 Gene

Entrez Gene Summary for MIR492 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR492 Gene

MIR492 (MicroRNA 492) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR492 Gene

Genomics for MIR492 Gene

Regulatory Elements for MIR492 Gene

Enhancers for MIR492 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G094792 0.6 Ensembl 11.9 -41.6 -41644 0.7 HLF CEBPB MAX CEBPG MNT ZNF384 ZNF316 CEBPA KDM1A MYC KRT19P2 MIR492 GC12M094805 GC12M094666
GH12G094972 0.5 ENCODE 10 +139.0 138974 1.7 BHLHE40 FOS HNF4A TBX21 NDUFA12 FGD6 KRT19P2 MIR492 TMCC3 ENSG00000258365 GC12M094957 LOC105369915
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR492 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR492 Gene

Chromosome:
12
Start:
94,834,398 bp from pter
End:
94,834,513 bp from pter
Size:
116 bases
Orientation:
Plus strand

Genomic View for MIR492 Gene

Genes around MIR492 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR492 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR492 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR492 Gene

Proteins for MIR492 Gene

Post-translational modifications for MIR492 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR492 Gene

Domains & Families for MIR492 Gene

Gene Families for MIR492 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR492: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR492 Gene

Function for MIR492 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR492 Gene

Localization for MIR492 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR492 Gene

Pathways & Interactions for MIR492 Gene

SuperPathways for MIR492 Gene

No Data Available

Interacting Proteins for MIR492 Gene

Gene Ontology (GO) - Biological Process for MIR492 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR492 Gene

Transcripts for MIR492 Gene

mRNA/cDNA for MIR492 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR492 Gene

No ASD Table

Relevant External Links for MIR492 Gene

GeneLoc Exon Structure for
MIR492
ECgene alternative splicing isoforms for
MIR492

Expression for MIR492 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR492 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR492 Gene:

MIR492
genes like me logo Genes that share expression patterns with MIR492: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR492 Gene

Orthologs for MIR492 Gene

Evolution for MIR492 Gene

ENSEMBL:
Gene Tree for MIR492 (if available)
TreeFam:
Gene Tree for MIR492 (if available)

No data available for Orthologs for MIR492 Gene

Paralogs for MIR492 Gene

No data available for Paralogs for MIR492 Gene

Variants for MIR492 Gene

Sequence variations from dbSNP and Humsavar for MIR492 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1003230487 -- 94,834,891(+) GGTCT(C/T)GAGAT nc-transcript-variant, downstream-variant-500B
rs1003235098 -- 94,833,667(+) GATCG(A/T)GTTCA upstream-variant-2KB
rs1003692152 -- 94,834,665(+) GGCCA(A/G)GTGGG nc-transcript-variant, downstream-variant-500B
rs1004751910 -- 94,834,919(+) TCAGC(A/G)TGAAA nc-transcript-variant, downstream-variant-500B
rs1005632063 -- 94,833,982(+) ATGAA(A/G)TGATA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR492 Gene

Variant ID Type Subtype PubMed ID
nsv1044757 CNV gain 25217958
nsv53265 CNV deletion 16902084
nsv7234 OTHER inversion 18451855

Relevant External Links for MIR492 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR492

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR492 Gene

Disorders for MIR492 Gene

Relevant External Links for MIR492

Genetic Association Database (GAD)
MIR492
Human Genome Epidemiology (HuGE) Navigator
MIR492
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR492

No disorders were found for MIR492 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR492 Gene

Publications for MIR492 Gene

  1. Genetic variation in MicroRNA genes and risk of oral premalignant lesions. (PMID: 19851984) Clague J. … Wu X. (Mol. Carcinog. 2010) 3 46 64
  2. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. (PMID: 20732906) Lin J. … Wu X. (Carcinogenesis 2010) 3 46 64
  3. Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk. (PMID: 19138993) Ye Y. … Wu X. (Cancer Prev Res (Phila) 2008) 3 46 64
  4. miR-492G>C polymorphism (rs2289030) is associated with overall survival of hepatocellular carcinoma patients. (PMID: 26753964) Yu G. … Jiang D.K. (Tumour Biol. 2016) 3 64
  5. Myeloid zinc-finger 1 (MZF-1) suppresses prostate tumor growth through enforcing ferroportin-conducted iron egress. (PMID: 25284586) Chen Y. … Liu S. (Oncogene 2015) 3 64

Products for MIR492 Gene

Sources for MIR492 Gene

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