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Aliases for MIR487A Gene

Subcategory (RNA class) for MIR487A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR487A Gene

  • MicroRNA 487a 2 3 5
  • MicroRNA 487 2
  • Hsa-Mir-487a 3
  • Hsa-Mir-487 3
  • Mir-487a 3
  • MIRN487A 3
  • MIRN487 3

External Ids for MIR487A Gene

ORGUL Members for MIR487A Gene

Previous HGNC Symbols for MIR487A Gene

  • MIRN487
  • MIRN487A

Previous GeneCards Identifiers for MIR487A Gene

  • GC14P100830
  • GC14P100920
  • GC14P101521
  • GC14P101550
  • GC14P101585
  • GC14P101624
  • GC14P101652
  • GC14P101685
  • GC14P101722
  • GC14P101764
  • GC14P101822
  • GC14P101962
  • GC14P102159
  • GC14P101262
  • GC14P101873
  • GC14P102193
  • GC14P102361
  • GC14P102532
  • GC14P102712
  • GC14P102885

Summaries for MIR487A Gene

Entrez Gene Summary for MIR487A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR487A Gene

MIR487A (MicroRNA 487a) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR487A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR487A Gene

Genomics for MIR487A Gene

GeneHancer (GH) Regulatory Elements for MIR487A Gene

Promoters and enhancers for MIR487A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I101004 Enhancer 0.7 Ensembl ENCODE 11 -47.4 -47361 1.9 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR154 MIR323B MIR485 MIR377 MIR496 MIR376C MIR1185-1 MIR1185-2
GH14I101096 Enhancer 0.7 FANTOM5 ENCODE 10.9 +45.9 45902 3.2 ATF4 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR409 MIR410 MIR412 MIR541 MIR656 MIR154
GH14I101176 Enhancer 0.5 ENCODE 10.7 +124.9 124920 2 ZNF680 ZFP3 RCOR1 CHD2 MIR154 MIR377 MIR496 MIR134 MIR323B MIR487A MIR485 SNORD113-2 SNORD113-3 ENSG00000222185
GH14I101008 Enhancer 0.2 ENCODE 11.1 -43.7 -43747 0.2 MIR487A MIR134 MIR323B MIR485 MIR154 MIR377 MIR496 MIR1185-1 MIR300 MIR376C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR487A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR487A Gene

Genomic Locations for MIR487A Gene
chr14:101,052,446-101,052,525
(GRCh38/hg38)
Size:
80 bases
Orientation:
Plus strand
chr14:101,518,783-101,518,862
(GRCh37/hg19)

Genomic View for MIR487A Gene

Genes around MIR487A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR487A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR487A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR487A Gene

Proteins for MIR487A Gene

Post-translational modifications for MIR487A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR487A Gene

Domains & Families for MIR487A Gene

Gene Families for MIR487A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR487A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR487A Gene

Function for MIR487A Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR487A Gene

Localization for MIR487A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR487A Gene

Pathways & Interactions for MIR487A Gene

SuperPathways for MIR487A Gene

No Data Available

Interacting Proteins for MIR487A Gene

Gene Ontology (GO) - Biological Process for MIR487A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR487A Gene

Drugs & Compounds for MIR487A Gene

No Compound Related Data Available

Transcripts for MIR487A Gene

mRNA/cDNA for MIR487A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR487A Gene

No ASD Table

Relevant External Links for MIR487A Gene

GeneLoc Exon Structure for
MIR487A
ECgene alternative splicing isoforms for
MIR487A

Expression for MIR487A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR487A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR487A Gene:

MIR487A
genes like me logo Genes that share expression patterns with MIR487A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR487A Gene

Orthologs for MIR487A Gene

Evolution for MIR487A Gene

ENSEMBL:
Gene Tree for MIR487A (if available)
TreeFam:
Gene Tree for MIR487A (if available)

No data available for Orthologs for MIR487A Gene

Paralogs for MIR487A Gene

No data available for Paralogs for MIR487A Gene

Variants for MIR487A Gene

Sequence variations from dbSNP and Humsavar for MIR487A Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1000145018 -- 101,051,981(+) C/G upstream_transcript_variant
rs1001554749 -- 101,051,043(+) C/A upstream_transcript_variant
rs1002100659 -- 101,051,658(+) T/C upstream_transcript_variant
rs1002153173 -- 101,051,448(+) C/A/T upstream_transcript_variant
rs1004228428 -- 101,050,515(+) T/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR487A Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR487A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR487A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR487A Gene

Disorders for MIR487A Gene

Additional Disease Information for MIR487A

No disorders were found for MIR487A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR487A Gene

Publications for MIR487A Gene

  1. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58
  2. MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2). (PMID: 23879965) Ma MT … Wei MJ (Cancer letters 2013) 3 58
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P … Tuschl T (Cell 2007) 3 58
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR487A Gene

Sources for MIR487A Gene

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