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Aliases for MIR487A Gene

Subcategory (RNA class) for MIR487A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR487A Gene

  • MicroRNA 487a 2 3 5
  • MicroRNA 487 2
  • Hsa-Mir-487a 3
  • Hsa-Mir-487 3
  • Mir-487a 3
  • MIRN487A 3
  • MIRN487 3

External Ids for MIR487A Gene

ORGUL Members for MIR487A Gene

Previous HGNC Symbols for MIR487A Gene

  • MIRN487
  • MIRN487A

Previous GeneCards Identifiers for MIR487A Gene

  • GC14P100830
  • GC14P100920
  • GC14P101521
  • GC14P101550
  • GC14P101585
  • GC14P101624
  • GC14P101652
  • GC14P101685
  • GC14P101722
  • GC14P101764
  • GC14P101822
  • GC14P101962
  • GC14P102159
  • GC14P101262
  • GC14P101873

Summaries for MIR487A Gene

Entrez Gene Summary for MIR487A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR487A Gene

MIR487A (MicroRNA 487a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR487A Gene

Genomics for MIR487A Gene

Genomic Location for MIR487A Gene

Chromosome:
14
Start:
101,052,424 bp from pter
End:
101,052,533 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR487A Gene

Genes around MIR487A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR487A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR487A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR487A Gene

No data available for Regulatory Elements for MIR487A Gene

Proteins for MIR487A Gene

Post-translational modifications for MIR487A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR487A Gene

Domains & Families for MIR487A Gene

Gene Families for MIR487A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR487A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR487A Gene

Function for MIR487A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR487A Gene

Localization for MIR487A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR487A Gene

Pathways & Interactions for MIR487A Gene

SuperPathways for MIR487A Gene

No Data Available

Interacting Proteins for MIR487A Gene

Gene Ontology (GO) - Biological Process for MIR487A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR487A Gene

Drugs & Compounds for MIR487A Gene

No Compound Related Data Available

Transcripts for MIR487A Gene

mRNA/cDNA for MIR487A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR487A Gene

No ASD Table

Relevant External Links for MIR487A Gene

GeneLoc Exon Structure for
MIR487A
ECgene alternative splicing isoforms for
MIR487A

Expression for MIR487A Gene

mRNA expression in normal human tissues for MIR487A Gene

genes like me logo Genes that share expression patterns with MIR487A: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR487A Gene

Orthologs for MIR487A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR487A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-487a 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-487a 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-487a 36
  • 98 (a)
OneToOne
Species with no ortholog for MIR487A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR487A Gene

ENSEMBL:
Gene Tree for MIR487A (if available)
TreeFam:
Gene Tree for MIR487A (if available)

Paralogs for MIR487A Gene

No data available for Paralogs for MIR487A Gene

Variants for MIR487A Gene

Sequence variations from dbSNP and Humsavar for MIR487A Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs753953405 -- 101,052,301(+) AGAAT(C/G)CATGG upstream-variant-2KB

Relevant External Links for MIR487A Gene

HapMap Linkage Disequilibrium report
MIR487A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR487A Gene

Disorders for MIR487A Gene

Relevant External Links for MIR487A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR487A

No disorders were found for MIR487A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR487A Gene

Publications for MIR487A Gene

  1. MiR-487a resensitizes mitoxantrone (MX)-resistant breast cancer cells (MCF-7/MX) to MX by targeting breast cancer resistance protein (BCRP/ABCG2). (PMID: 23879965) Ma M.T. … Wei M.J. (Cancer Lett. 2013) 3 67
  2. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3

Products for MIR487A Gene

Sources for MIR487A Gene

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