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Aliases for MIR485 Gene

Subcategory (RNA class) for MIR485 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR485 Gene

  • MicroRNA 485 2 3 5
  • Hsa-Mir-485 3
  • Mir-485 3
  • MIRN485 3

External Ids for MIR485 Gene

ORGUL Members for MIR485 Gene

Previous HGNC Symbols for MIR485 Gene

  • MIRN485

Previous GeneCards Identifiers for MIR485 Gene

  • GC14P100834
  • GC14P100924
  • GC14P101525
  • GC14P101554
  • GC14P101589
  • GC14P101628
  • GC14P101656
  • GC14P101690
  • GC14P101728
  • GC14P101768
  • GC14P101826
  • GC14P101966
  • GC14P102163
  • GC14P101267
  • GC14P101876
  • GC14P102199
  • GC14P102367
  • GC14P102537
  • GC14P102716
  • GC14P102889

Summaries for MIR485 Gene

Entrez Gene Summary for MIR485 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR485 Gene

MIR485 (MicroRNA 485) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway.

Additional gene information for MIR485 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR485 Gene

Genomics for MIR485 Gene

GeneHancer (GH) Regulatory Elements for MIR485 Gene

Promoters and enhancers for MIR485 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I101004 Enhancer 0.7 Ensembl ENCODE 11 -50.3 -50334 1.9 GATA3 MNT MYC TCF7L2 MIR134 MIR487A MIR154 MIR323B MIR485 MIR377 MIR496 MIR376C MIR1185-2 MIR300
GH14I101096 Enhancer 0.7 FANTOM5 ENCODE 10.9 +42.9 42929 3.2 ATF4 POLR2A JUN MAFK RTL1 LOC105370670 MEG9 MIR369 MIR541 MIR656 MIR412 MIR410 MIR409 MIR154
GH14I101176 Enhancer 0.5 ENCODE 10.7 +121.9 121947 2 ZNF680 ZFP3 RCOR1 CHD2 MIR496 MIR377 MIR154 MIR485 MIR134 MIR487A MIR323B SNORD113-2 SNORD113-3 ENSG00000222185
GH14I101008 Enhancer 0.2 ENCODE 11 -46.7 -46720 0.2 MIR487A MIR134 MIR323B MIR485 MIR154 MIR377 MIR496 MIR1185-1 MIR300 MIR376C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR485 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR485 Gene

Genomic Locations for MIR485 Gene
chr14:101,055,419-101,055,491
(GRCh38/hg38)
Size:
73 bases
Orientation:
Plus strand
chr14:101,521,738-101,521,848
(GRCh37/hg19)

Genomic View for MIR485 Gene

Genes around MIR485 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR485 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR485 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR485 Gene

Proteins for MIR485 Gene

Post-translational modifications for MIR485 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR485 Gene

Domains & Families for MIR485 Gene

Gene Families for MIR485 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR485: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR485 Gene

Function for MIR485 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR485 Gene

Localization for MIR485 Gene

Gene Ontology (GO) - Cellular Components for MIR485 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR485: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR485 Gene

Pathways & Interactions for MIR485 Gene

SuperPathways for MIR485 Gene

SuperPathway Contained pathways
1 Parkinsons Disease Pathway
genes like me logo Genes that share pathways with MIR485: view

Pathways by source for MIR485 Gene

1 BioSystems pathway for MIR485 Gene

Interacting Proteins for MIR485 Gene

Gene Ontology (GO) - Biological Process for MIR485 Gene

None

No data available for SIGNOR curated interactions for MIR485 Gene

Drugs & Compounds for MIR485 Gene

No Compound Related Data Available

Transcripts for MIR485 Gene

mRNA/cDNA for MIR485 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR485 Gene

No ASD Table

Relevant External Links for MIR485 Gene

GeneLoc Exon Structure for
MIR485
ECgene alternative splicing isoforms for
MIR485

Expression for MIR485 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR485 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR485 Gene:

MIR485
genes like me logo Genes that share expression patterns with MIR485: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR485 Gene

Orthologs for MIR485 Gene

Evolution for MIR485 Gene

ENSEMBL:
Gene Tree for MIR485 (if available)
TreeFam:
Gene Tree for MIR485 (if available)

No data available for Orthologs for MIR485 Gene

Paralogs for MIR485 Gene

No data available for Paralogs for MIR485 Gene

Variants for MIR485 Gene

Sequence variations from dbSNP and Humsavar for MIR485 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1001787824 -- 101,053,450(+) A/G upstream_transcript_variant
rs1002933201 -- 101,054,171(+) G/C upstream_transcript_variant
rs1003488050 -- 101,054,234(+) G/A upstream_transcript_variant
rs1003864116 -- 101,054,505(+) G/T upstream_transcript_variant
rs1005576245 -- 101,055,284(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR485 Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR485 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR485

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR485 Gene

Disorders for MIR485 Gene

Additional Disease Information for MIR485

No disorders were found for MIR485 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR485 Gene

Publications for MIR485 Gene

  1. Low serum level of miR-485-3p predicts poor survival in patients with glioblastoma. (PMID: 28931080) Wang ZQ … Wu SX (PloS one 2017) 3 58
  2. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  3. Hydrogen sulfide protects against TNF-α induced neuronal cell apoptosis through miR-485-5p/TRADD signaling. (PMID: 27562714) Chen Z … Sun Z (Biochemical and biophysical research communications 2016) 3 58
  4. MiR-485 inhibits metastasis and EMT of lung adenocarcinoma by targeting Flot2. (PMID: 27262438) Mou X … Liu S (Biochemical and biophysical research communications 2016) 3 58
  5. MiR-485-3p and miR-485-5p suppress breast cancer cell metastasis by inhibiting PGC-1α expression. (PMID: 27010860) Lou C … Li Z (Cell death & disease 2016) 3 58

Products for MIR485 Gene

Sources for MIR485 Gene

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