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Aliases for MIR484 Gene

Subcategory (RNA class) for MIR484 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR484 Gene

  • MicroRNA 484 2 3 5
  • Hsa-Mir-484 3
  • Mir-484 3
  • MIRN484 3

External Ids for MIR484 Gene

Previous HGNC Symbols for MIR484 Gene

  • MIRN484

Previous GeneCards Identifiers for MIR484 Gene

  • GC16P015645
  • GC16P015737

Summaries for MIR484 Gene

Entrez Gene Summary for MIR484 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR484 Gene

MIR484 (MicroRNA 484) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR484 Gene

Genomics for MIR484 Gene

Genomic Location for MIR484 Gene

Chromosome:
16
Start:
15,643,281 bp from pter
End:
15,643,390 bp from pter
Size:
110 bases
Orientation:
Plus strand

Genomic View for MIR484 Gene

Genes around MIR484 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR484 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR484 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR484 Gene

No data available for Regulatory Elements for MIR484 Gene

Proteins for MIR484 Gene

Post-translational modifications for MIR484 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR484 Gene

Domains & Families for MIR484 Gene

Gene Families for MIR484 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR484: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR484 Gene

Function for MIR484 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR484 Gene

Localization for MIR484 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR484 Gene

Pathways & Interactions for MIR484 Gene

SuperPathways for MIR484 Gene

No Data Available

Interacting Proteins for MIR484 Gene

Gene Ontology (GO) - Biological Process for MIR484 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR484 Gene

Drugs & Compounds for MIR484 Gene

No Compound Related Data Available

Transcripts for MIR484 Gene

mRNA/cDNA for MIR484 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR484 Gene

No ASD Table

Relevant External Links for MIR484 Gene

GeneLoc Exon Structure for
MIR484
ECgene alternative splicing isoforms for
MIR484

Expression for MIR484 Gene

mRNA expression in normal human tissues for MIR484 Gene

genes like me logo Genes that share expression patterns with MIR484: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR484 Gene

Orthologs for MIR484 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR484 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-484 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir484 36
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-484 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR484:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR484 Gene

ENSEMBL:
Gene Tree for MIR484 (if available)
TreeFam:
Gene Tree for MIR484 (if available)

Paralogs for MIR484 Gene

No data available for Paralogs for MIR484 Gene

Variants for MIR484 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR484 Gene

Variant ID Type Subtype PubMed ID
nsv435664 CNV Deletion 17901297
esv2714015 CNV Deletion 23290073
dgv2610n71 CNV Gain 21882294
nsv457428 CNV Gain 19166990
nsv469626 CNV Loss 16826518

Relevant External Links for MIR484 Gene

HapMap Linkage Disequilibrium report
MIR484

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR484 Gene

Disorders for MIR484 Gene

Relevant External Links for MIR484

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR484

No disorders were found for MIR484 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR484 Gene

Publications for MIR484 Gene

  1. The significance of detection of serum miR-423-5p and miR-484 for diagnosis of colorectal cancer. (PMID: 25807655) Lu X. … Lu J. (Clin. Lab. 2015) 3
  2. MicroRNA-484 is more highly expressed in serum of early breast cancer patients compared to healthy volunteers. (PMID: 24641801) Zearo S. … Soon P.S.h. (BMC Cancer 2014) 3
  3. A microRNA signature defines chemoresistance in ovarian cancer through modulation of angiogenesis. (PMID: 23697367) Vecchione A. … Croce C.M. (Proc. Natl. Acad. Sci. U.S.A. 2013) 3
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR484 Gene

Sources for MIR484 Gene

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