Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR484 Gene

Subcategory (RNA class) for MIR484 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR484 Gene

  • MicroRNA 484 2 3 5
  • Hsa-Mir-484 3
  • Mir-484 3
  • MIRN484 3

External Ids for MIR484 Gene

Previous HGNC Symbols for MIR484 Gene

  • MIRN484

Previous GeneCards Identifiers for MIR484 Gene

  • GC16P015645
  • GC16P015737
  • GC16P015646
  • GC16P015652

Summaries for MIR484 Gene

Entrez Gene Summary for MIR484 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR484 Gene

MIR484 (MicroRNA 484) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic.

Additional gene information for MIR484 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR484 Gene

Genomics for MIR484 Gene

Regulatory Elements for MIR484 Gene

Enhancers for MIR484 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16H015649 1.1 ENCODE 0.4 +7.4 7394 2 HDGF PKNOX1 ARNT ARID4B SIN3A YBX1 DMAP1 SLC30A9 CBX5 FOS ABCC1 LOC100505915 ENSG00000262171 ENSG00000263335 MPV17L C16orf45 GC16P015657 MIR484
GH16H015648 0.4 ENCODE 0.4 +5.0 5025 0 ZNF133 GC16P015657 MIR484
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR484 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR484 Gene

Chromosome:
16
Start:
15,643,294 bp from pter
End:
15,643,372 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR484 Gene

Genes around MIR484 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR484 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR484 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR484 Gene

Proteins for MIR484 Gene

Post-translational modifications for MIR484 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR484 Gene

Domains & Families for MIR484 Gene

Gene Families for MIR484 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR484: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR484 Gene

Function for MIR484 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR484
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR484 Gene

Localization for MIR484 Gene

Gene Ontology (GO) - Cellular Components for MIR484 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR484: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR484 Gene

Drugs & Compounds for MIR484 Gene

No Compound Related Data Available

Transcripts for MIR484 Gene

mRNA/cDNA for MIR484 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR484
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR484 Gene

No ASD Table

Relevant External Links for MIR484 Gene

GeneLoc Exon Structure for
MIR484
ECgene alternative splicing isoforms for
MIR484

Expression for MIR484 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR484 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR484 Gene:

MIR484
genes like me logo Genes that share expression patterns with MIR484: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR484 Gene

Orthologs for MIR484 Gene

Evolution for MIR484 Gene

ENSEMBL:
Gene Tree for MIR484 (if available)
TreeFam:
Gene Tree for MIR484 (if available)

No data available for Orthologs for MIR484 Gene

Paralogs for MIR484 Gene

No data available for Paralogs for MIR484 Gene

Variants for MIR484 Gene

Sequence variations from dbSNP and Humsavar for MIR484 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs77774475 Likely benign 15,643,548(+) TTTCA(A/G)TGAAA downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs79063947 Likely benign 15,643,529(+) GAAGG(C/G/T)GATTT downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs886051712 Likely benign 15,643,558(+) AAACC(-/C)TGTCC downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs138559781 Uncertain significance 15,643,740(+) CGCAA(A/G)GTTGC downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime
rs187630586 Uncertain significance 15,643,558(+) AAACC(A/C)TGTCC downstream-variant-500B, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR484 Gene

Variant ID Type Subtype PubMed ID
dgv4924n54 CNV gain 21841781
esv2714015 CNV deletion 23290073
nsv1047898 CNV loss 25217958
nsv1049647 CNV gain+loss 25217958
nsv1125134 CNV deletion 24896259
nsv435664 CNV deletion 17901297
nsv457428 CNV gain 19166990
nsv469626 CNV loss 16826518

Relevant External Links for MIR484 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR484

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR484 Gene

Disorders for MIR484 Gene

Relevant External Links for MIR484

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR484

No disorders were found for MIR484 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR484 Gene

Publications for MIR484 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  2. miR-155 and miR-484 Are Associated with Time to Progression in Metastatic Renal Cell Carcinoma Treated with Sunitinib. (PMID: 26064968) Merhautova J … Slaby O (BioMed research international 2015) 3 60
  3. The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival and clinical outcome in CLL. (PMID: 25936528) Vasyutina E … Herling M (Leukemia 2015) 3 60
  4. The significance of detection of serum miR-423-5p and miR-484 for diagnosis of colorectal cancer. (PMID: 25807655) Lu X … Lu J (Clinical laboratory 2015) 3 60
  5. Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer. (PMID: 25643696) Ye FG … Shao ZM (Cancer research 2015) 3 60

Products for MIR484 Gene

Sources for MIR484 Gene

Content
Loading form....