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Aliases for MIR483 Gene

Subcategory (RNA class) for MIR483 Gene


Quality Score for this RNA gene is


Aliases for MIR483 Gene

  • MicroRNA 483 2 3
  • Hsa-Mir-483 3
  • MIRN483 3

External Ids for MIR483 Gene

Previous HGNC Symbols for MIR483 Gene

  • MIRN483

Previous GeneCards Identifiers for MIR483 Gene

  • GC11M002115
  • GC11M002117
  • GC11M002155

Summaries for MIR483 Gene

Entrez Gene Summary for MIR483 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR483 Gene

MIR483 (MicroRNA 483) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR483 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR483 Gene

Genomics for MIR483 Gene

Genomic Location for MIR483 Gene

2,134,111 bp from pter
2,134,222 bp from pter
112 bases
Minus strand

Genomic View for MIR483 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR483 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR483 Gene

No data available for Regulatory Elements for MIR483 Gene

Proteins for MIR483 Gene

Post-translational modifications for MIR483 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR483 Gene

Domains for MIR483 Gene

Gene Families for MIR483 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR483: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR483 Gene

Function for MIR483 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR483 Gene

Localization for MIR483 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR483 Gene

Pathways for MIR483 Gene

SuperPathways for MIR483 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR483: view

Pathways by source for MIR483 Gene

1 KEGG pathway for MIR483 Gene

Interacting Proteins for MIR483 Gene

Gene Ontology (GO) - Biological Process for MIR483 Gene


Transcripts for MIR483 Gene

mRNA/cDNA for MIR483 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR483 Gene

No ASD Table

Relevant External Links for MIR483 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR483 Gene

mRNA expression in normal human tissues for MIR483 Gene

genes like me logo Genes that share expressions with MIR483: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR483 Gene

Orthologs for MIR483 Gene

Evolution for MIR483 Gene

Gene Tree for MIR483 (if available)
Gene Tree for MIR483 (if available)

No data available for Orthologs for MIR483 Gene

Paralogs for MIR483 Gene

No data available for Paralogs for MIR483 Gene

Variants for MIR483 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR483 Gene

Variant ID Type Subtype PubMed ID
nsv467645 CNV Gain 19166990
dgv992n71 CNV Loss 21882294
dgv993n71 CNV Loss 21882294
nsv896776 CNV Loss 21882294
dgv994n71 CNV Loss 21882294
dgv995n71 CNV Loss 21882294
nsv825707 CNV Gain 20364138
dgv996n71 CNV Loss 21882294

Relevant External Links for MIR483 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR483 Gene

Disorders for MIR483 Gene

No disorders were found for MIR483 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR483 Gene

Publications for MIR483 Gene

  1. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Oncogenic role of miR-483-3p at the IGF2/483 locus. (PMID: 20388800) Veronese A. … Negrini M. (Cancer Res. 2010) 3
  5. MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancer. (PMID: 21112326) Hao J. … Shao C. (FEBS Lett. 2011) 3

Products for MIR483 Gene

Sources for MIR483 Gene

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