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Aliases for MIR4793 Gene

Subcategory (RNA class) for MIR4793 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4793 Gene

  • MicroRNA 4793 2 3 5
  • Hsa-Mir-4793 3

External Ids for MIR4793 Gene

Previous GeneCards Identifiers for MIR4793 Gene

  • GC03U901784

Summaries for MIR4793 Gene

Entrez Gene Summary for MIR4793 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4793 Gene

MIR4793 (MicroRNA 4793) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are GPCRs, Other.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4793 Gene

Genomics for MIR4793 Gene

Regulatory Elements for MIR4793 Gene

Enhancers for MIR4793 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03G048654 1.1 Ensembl ENCODE 0.4 -12.1 -12128 2.8 ARID4B SIN3A RAD21 ETS1 ZNF143 ZNF207 FOS CREM EGR2 SP5 WDR6 TMEM89 UQCRC1 NCKIPSD FBXW12 PRKAR2A-AS1 PRKAR2A CDC25A PIR43914 MIR4793
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4793 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4793 Gene

Chromosome:
3
Start:
48,644,194 bp from pter
End:
48,644,280 bp from pter
Size:
87 bases
Orientation:
Minus strand

Genomic View for MIR4793 Gene

Genes around MIR4793 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4793 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4793 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4793 Gene

ORGUL Member Location for MIR4793 Gene

ORGUL Member Location for MIR4793 gene

Proteins for MIR4793 Gene

Post-translational modifications for MIR4793 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4793 Gene

Domains & Families for MIR4793 Gene

Gene Families for MIR4793 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4793: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4793 Gene

Function for MIR4793 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4793 Gene

Localization for MIR4793 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4793 Gene

Pathways & Interactions for MIR4793 Gene

SuperPathways for MIR4793 Gene

SuperPathway Contained pathways
1 GPCRs, Other
genes like me logo Genes that share pathways with MIR4793: view

Pathways by source for MIR4793 Gene

1 BioSystems pathway for MIR4793 Gene

Interacting Proteins for MIR4793 Gene

Gene Ontology (GO) - Biological Process for MIR4793 Gene

None

No data available for SIGNOR curated interactions for MIR4793 Gene

Drugs & Compounds for MIR4793 Gene

No Compound Related Data Available

Transcripts for MIR4793 Gene

mRNA/cDNA for MIR4793 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4793 Gene

No ASD Table

Relevant External Links for MIR4793 Gene

GeneLoc Exon Structure for
MIR4793
ECgene alternative splicing isoforms for
MIR4793

Expression for MIR4793 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4793 Gene

mRNA differential expression in normal tissues according to GTEx for MIR4793 Gene

This gene is overexpressed in Brain - Cerebellum (x10.5), Brain - Cerebellar Hemisphere (x7.9), and Pituitary (x6.1).

NURSA nuclear receptor signaling pathways regulating expression of MIR4793 Gene:

MIR4793
genes like me logo Genes that share expression patterns with MIR4793: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4793 Gene

Orthologs for MIR4793 Gene

Evolution for MIR4793 Gene

ENSEMBL:
Gene Tree for MIR4793 (if available)
TreeFam:
Gene Tree for MIR4793 (if available)

No data available for Orthologs for MIR4793 Gene

Paralogs for MIR4793 Gene

No data available for Paralogs for MIR4793 Gene

Variants for MIR4793 Gene

Sequence variations from dbSNP and Humsavar for MIR4793 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs149614835 Uncertain significance 48,645,117(+) ACCTG(C/T)ATGCG upstream-variant-2KB, reference, missense
rs1000301493 -- 48,644,588(+) GGACA(C/G)AAAAA intron-variant, upstream-variant-2KB
rs1000418842 -- 48,644,371(+) CAGAG(A/G)GAGAC intron-variant, upstream-variant-2KB
rs1001462791 -- 48,644,510(+) GGCAG(C/G)GACAG intron-variant, upstream-variant-2KB
rs1001584492 -- 48,643,835(+) AGATG(G/T)GAGGT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4793 Gene

Variant ID Type Subtype PubMed ID
nsv523981 CNV loss 19592680
nsv590246 CNV loss 21841781
nsv590247 CNV loss 21841781
nsv818138 CNV gain 17921354
nsv834685 CNV loss 17160897
nsv954485 CNV deletion 24416366

Relevant External Links for MIR4793 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4793

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4793 Gene

Disorders for MIR4793 Gene

Relevant External Links for MIR4793

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4793

No disorders were found for MIR4793 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4793 Gene

Publications for MIR4793 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4793 Gene

Sources for MIR4793 Gene

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