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Aliases for MIR4784 Gene

Subcategory (RNA class) for MIR4784 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4784 Gene

  • MicroRNA 4784 2 3 5
  • Hsa-Mir-4784 3

External Ids for MIR4784 Gene

Previous GeneCards Identifiers for MIR4784 Gene

  • GC02U902417
  • GC02M132300
  • GC02M132313
  • GC02M132334

Summaries for MIR4784 Gene

Entrez Gene Summary for MIR4784 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4784 Gene

MIR4784 (MicroRNA 4784) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4784 Gene

Genomics for MIR4784 Gene

Regulatory Elements for MIR4784 Gene

Enhancers for MIR4784 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G131490 1.4 ENCODE dbSUPER 0.7 -1.3 -1334 3.9 HDGF HNRNPUL1 FOXA2 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZBTB7B LOC150776 MZT2A ENSG00000272769 MIR4784
GH02G131488 0.6 dbSUPER 0.7 +2.4 2415 1.1 POLR2A SMARCA4 EGR1 ZBTB33 REST RBFOX2 EGR2 MZT2A MIR4784 TUBA3D
GH02G131478 0.4 dbSUPER 0.4 +12.5 12512 0.9 FOS LOC150776 MZT2A TUBA3D MIR4784
GH02G131479 0.2 dbSUPER 0.4 +11.8 11794 0.4 MZT2A TUBA3D MIR4784
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4784 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4784 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000123165 -1564 2801 HDGF HNRNPUL1 FOXA2 ARNT CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZBTB7B

Genomic Location for MIR4784 Gene

Chromosome:
2
Start:
131,491,160 bp from pter
End:
131,491,236 bp from pter
Size:
77 bases
Orientation:
Minus strand

Genomic View for MIR4784 Gene

Genes around MIR4784 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4784 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4784 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4784 Gene

ORGUL Member Location for MIR4784 Gene

ORGUL Member Location for MIR4784 gene

Proteins for MIR4784 Gene

Post-translational modifications for MIR4784 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4784 Gene

Domains & Families for MIR4784 Gene

Gene Families for MIR4784 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4784: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4784 Gene

Function for MIR4784 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4784 Gene

Localization for MIR4784 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4784 Gene

Pathways & Interactions for MIR4784 Gene

SuperPathways for MIR4784 Gene

No Data Available

Interacting Proteins for MIR4784 Gene

Gene Ontology (GO) - Biological Process for MIR4784 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4784 Gene

Transcripts for MIR4784 Gene

mRNA/cDNA for MIR4784 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4784 Gene

No ASD Table

Relevant External Links for MIR4784 Gene

GeneLoc Exon Structure for
MIR4784
ECgene alternative splicing isoforms for
MIR4784

Expression for MIR4784 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4784 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4784 Gene:

MIR4784
genes like me logo Genes that share expression patterns with MIR4784: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4784 Gene

Orthologs for MIR4784 Gene

Evolution for MIR4784 Gene

ENSEMBL:
Gene Tree for MIR4784 (if available)
TreeFam:
Gene Tree for MIR4784 (if available)

No data available for Orthologs for MIR4784 Gene

Paralogs for MIR4784 Gene

No data available for Paralogs for MIR4784 Gene

Variants for MIR4784 Gene

Sequence variations from dbSNP and Humsavar for MIR4784 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1001364199 -- 131,493,132(+) TATGG(A/G)TCCCA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1001427922 -- 131,492,791(+) GGGGT(-/G)GGGGG intron-variant, upstream-variant-2KB
rs1005723578 -- 131,492,399(+) AGGTG(-/CGCCCCGCCC)CGCCG intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, frameshift-variant, utr-variant-5-prime
rs1008316047 -- 131,493,198(+) GCGAG(C/T)CCCTG intron-variant, upstream-variant-2KB
rs1008514015 -- 131,492,504(+) CGCGG(A/G)GACGG intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR4784 Gene

Variant ID Type Subtype PubMed ID
dgv4075n100 CNV gain 25217958
dgv4077n100 CNV gain 25217958
dgv4079n100 CNV loss 25217958
dgv4080n100 CNV gain 25217958
dgv476n27 CNV loss 19166990
esv2670824 CNV deletion 23128226
esv2759092 CNV gain+loss 17122850
esv2760576 CNV gain+loss 21179565
esv34412 CNV gain 17911159
esv34704 CNV gain 17911159
esv3575300 CNV gain 25503493
esv3584079 CNV loss 25503493
esv3592483 CNV loss 21293372
esv3592484 CNV gain 21293372
esv3893359 CNV gain+loss 25118596
nsv1002963 CNV gain 25217958
nsv1006738 CNV gain 25217958
nsv1008539 CNV gain 25217958
nsv1014682 CNV loss 25217958
nsv428404 CNV loss 18775914
nsv459396 CNV gain 19166990
nsv470486 CNV loss 18288195
nsv524021 CNV loss 19592680
nsv583140 CNV gain 21841781
nsv583143 CNV gain+loss 21841781
nsv583145 CNV loss 21841781
nsv7327 OTHER inversion 18451855
nsv834376 CNV gain 17160897
nsv979124 CNV duplication 23825009
nsv997248 CNV loss 25217958

Relevant External Links for MIR4784 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4784

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4784 Gene

Disorders for MIR4784 Gene

Relevant External Links for MIR4784

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4784

No disorders were found for MIR4784 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4784 Gene

Publications for MIR4784 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4784 Gene

Sources for MIR4784 Gene

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