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Aliases for MIR4783 Gene

Subcategory (RNA class) for MIR4783 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4783 Gene

  • MicroRNA 4783 2 3 5
  • Hsa-Mir-4783 3

External Ids for MIR4783 Gene

Previous GeneCards Identifiers for MIR4783 Gene

  • GC02U902423
  • GC02M128184

Summaries for MIR4783 Gene

Entrez Gene Summary for MIR4783 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4783 Gene

MIR4783 (MicroRNA 4783) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4783 Gene

Genomics for MIR4783 Gene

Regulatory Elements for MIR4783 Gene

Enhancers for MIR4783 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F127437 1 ENCODE 0.4 -14.8 -14753 1.3 ATF1 MLX ARID4B DMAP1 ZNF48 YY1 SLC30A9 ZNF143 SP5 NFYC ERCC3 ENSG00000236682 MAP3K2 RNU4-48P BIN1 LIMS2 MIR4783 LOC105373607
GH02F127455 1.3 Ensembl ENCODE 0.3 -31.7 -31743 2.6 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 SP5 NFYC PROC LIMS2 ERCC3 MAP3K2 ENSG00000236682 LOC105373607 MIR4783
GH02F127453 0.8 ENCODE 0.3 -29.9 -29922 0.2 ELF3 CTCF PKNOX1 SAP130 TAL1 ARID4B CEBPG DMAP1 ZNF48 RAD21 PROC LOC105373607 MIR4783
GH02F127454 0.8 ENCODE 0.3 -30.1 -30142 0.2 ELF3 PKNOX1 ARID4B DMAP1 ZNF48 DNMT3B RAD21 YY1 SLC30A9 GATA2 PROC LOC105373607 MIR4783
GH02F127449 0.5 FANTOM5 0.3 -26.2 -26190 0.4 ZNF316 HLF CEBPB MAFK PROC RNU4-48P ERCC3 LIMS2 LOC105373607 MIR4783
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4783 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4783 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001826985 218 1201 CTCF KLF1 MXI1 MAX ZIC2 E2F1 GLIS2 POLR2A EZH2 BHLHE40

Genomic Location for MIR4783 Gene

Chromosome:
2
Start:
127,423,537 bp from pter
End:
127,423,618 bp from pter
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR4783 Gene

Genes around MIR4783 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4783 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4783 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4783 Gene

ORGUL Member Location for MIR4783 Gene

ORGUL Member Location for MIR4783 gene

Proteins for MIR4783 Gene

Post-translational modifications for MIR4783 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4783 Gene

Domains & Families for MIR4783 Gene

Gene Families for MIR4783 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4783: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4783 Gene

Function for MIR4783 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4783 Gene

Localization for MIR4783 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4783 Gene

Pathways & Interactions for MIR4783 Gene

SuperPathways for MIR4783 Gene

No Data Available

Interacting Proteins for MIR4783 Gene

Gene Ontology (GO) - Biological Process for MIR4783 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4783 Gene

Transcripts for MIR4783 Gene

mRNA/cDNA for MIR4783 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4783 Gene

No ASD Table

Relevant External Links for MIR4783 Gene

GeneLoc Exon Structure for
MIR4783
ECgene alternative splicing isoforms for
MIR4783

Expression for MIR4783 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4783 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4783 Gene:

MIR4783
genes like me logo Genes that share expression patterns with MIR4783: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4783 Gene

Orthologs for MIR4783 Gene

Evolution for MIR4783 Gene

ENSEMBL:
Gene Tree for MIR4783 (if available)
TreeFam:
Gene Tree for MIR4783 (if available)

No data available for Orthologs for MIR4783 Gene

Paralogs for MIR4783 Gene

No data available for Paralogs for MIR4783 Gene

Variants for MIR4783 Gene

Sequence variations from dbSNP and Humsavar for MIR4783 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs121918159 Pathogenic 127,423,319(+) CACGC(A/C)TTACT downstream-variant-500B, reference, missense
rs200234655 Uncertain significance 127,423,093(+) GCGGG(A/C)ACGGC downstream-variant-500B, reference, missense
rs374476971 Uncertain significance 127,423,111(+) TCGAC(C/G)GCATC downstream-variant-500B, reference, missense
rs774908523 Uncertain significance 127,423,057(+) TCTTG(C/T)CCTTG downstream-variant-500B, reference, missense
rs5936 Benign 127,423,296(+) TGCTC(G/T)CTGGA downstream-variant-500B, reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for MIR4783 Gene

Variant ID Type Subtype PubMed ID
nsv583036 CNV gain 21841781

Relevant External Links for MIR4783 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4783

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4783 Gene

Disorders for MIR4783 Gene

Relevant External Links for MIR4783

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4783

No disorders were found for MIR4783 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4783 Gene

Publications for MIR4783 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4783 Gene

Sources for MIR4783 Gene

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