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Aliases for MIR4781 Gene

Subcategory (RNA class) for MIR4781 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4781 Gene

  • MicroRNA 4781 2 3 5
  • Hsa-Mir-4781 3
  • Mir-4781 3

External Ids for MIR4781 Gene

Previous GeneCards Identifiers for MIR4781 Gene

  • GC01U903261
  • GC01P054524

Summaries for MIR4781 Gene

Entrez Gene Summary for MIR4781 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4781 Gene

MIR4781 (MicroRNA 4781) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4781 Gene

Genomics for MIR4781 Gene

Regulatory Elements for MIR4781 Gene

Enhancers for MIR4781 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G054069 0.9 ENCODE 0.4 +16.1 16137 1.0 ELF3 FOXA2 RB1 ARID4B RAD21 RARA ZNF143 CREM MIXL1 ZNF654 TCEANC2 GC01P054077 MIR4781
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4781 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4781 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000006585 -1079 2801 CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 ZNF548 ZNF263 SP3

Genomic Location for MIR4781 Gene

Chromosome:
1
Start:
54,054,079 bp from pter
End:
54,054,154 bp from pter
Size:
76 bases
Orientation:
Plus strand

Genomic View for MIR4781 Gene

Genes around MIR4781 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4781 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4781 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4781 Gene

Proteins for MIR4781 Gene

Post-translational modifications for MIR4781 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4781 Gene

Domains & Families for MIR4781 Gene

Gene Families for MIR4781 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4781: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4781 Gene

Function for MIR4781 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4781 Gene

Localization for MIR4781 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4781 Gene

Pathways & Interactions for MIR4781 Gene

SuperPathways for MIR4781 Gene

No Data Available

Interacting Proteins for MIR4781 Gene

Gene Ontology (GO) - Biological Process for MIR4781 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4781 Gene

Drugs & Compounds for MIR4781 Gene

No Compound Related Data Available

Transcripts for MIR4781 Gene

mRNA/cDNA for MIR4781 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4781 Gene

No ASD Table

Relevant External Links for MIR4781 Gene

GeneLoc Exon Structure for
MIR4781
ECgene alternative splicing isoforms for
MIR4781

Expression for MIR4781 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4781 Gene:

MIR4781
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4781 Gene

Orthologs for MIR4781 Gene

Evolution for MIR4781 Gene

ENSEMBL:
Gene Tree for MIR4781 (if available)
TreeFam:
Gene Tree for MIR4781 (if available)

No data available for Orthologs for MIR4781 Gene

Paralogs for MIR4781 Gene

No data available for Paralogs for MIR4781 Gene

Variants for MIR4781 Gene

Sequence variations from dbSNP and Humsavar for MIR4781 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000455349 -- 54,052,150(+) ATACA(C/T)GGGAA intron-variant, upstream-variant-2KB
rs1000493559 -- 54,052,254(+) AAAAG(-/A)AAGGG intron-variant, upstream-variant-2KB
rs1000824487 -- 54,052,435(+) CGTCT(C/T)GGACA intron-variant, upstream-variant-2KB
rs1002449396 -- 54,054,631(+) GCCTC(C/G)TCCTC intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1004390893 -- 54,054,165(+) AGCTA(A/G)GAACC intron-variant, downstream-variant-500B, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4781 Gene

Variant ID Type Subtype PubMed ID
nsv1011262 CNV gain 25217958

Relevant External Links for MIR4781 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4781

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4781 Gene

Disorders for MIR4781 Gene

Relevant External Links for MIR4781

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4781

No disorders were found for MIR4781 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4781 Gene

Publications for MIR4781 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4781 Gene

Sources for MIR4781 Gene

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