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Aliases for MIR4775 Gene

Subcategory (RNA class) for MIR4775 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4775 Gene

  • MicroRNA 4775 2 3 5
  • Hsa-Mir-4775 3

External Ids for MIR4775 Gene

Previous GeneCards Identifiers for MIR4775 Gene

  • GC02U902422
  • GC02P208621

Summaries for MIR4775 Gene

Entrez Gene Summary for MIR4775 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4775 Gene

MIR4775 (MicroRNA 4775) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4775 Gene

Genomics for MIR4775 Gene

Regulatory Elements for MIR4775 Gene

Enhancers for MIR4775 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02G207762 1.4 ENCODE dbSUPER 0.4 +12.9 12920 10.0 HNRNPUL1 FOXA2 MLX CREB3L1 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 METTL21A PLEKHM3 FZD5 MIR4775
GH02G207758 0.7 FANTOM5 dbSUPER 0.7 +3.5 3475 0.3 HMBOX1 RBFOX2 PLEKHM3 CCNYL1 MIR4775 FZD5
GH02G207757 0.5 dbSUPER 0.7 +2.5 2511 0.3 ZBTB33 MAFK ATF2 PLEKHM3 CCNYL1 MIR4775 FZD5
GH02G207759 0.4 dbSUPER 0.7 +4.3 4309 0.4 MXD3 PLEKHM3 CCNYL1 MIR4775 FZD5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4775 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4775 Gene

Chromosome:
2
Start:
207,754,807 bp from pter
End:
207,754,881 bp from pter
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR4775 Gene

Genes around MIR4775 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4775 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4775 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4775 Gene

Proteins for MIR4775 Gene

Post-translational modifications for MIR4775 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4775 Gene

Domains & Families for MIR4775 Gene

Gene Families for MIR4775 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4775: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4775 Gene

Function for MIR4775 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4775 Gene

Localization for MIR4775 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4775 Gene

Pathways & Interactions for MIR4775 Gene

SuperPathways for MIR4775 Gene

No Data Available

Interacting Proteins for MIR4775 Gene

Gene Ontology (GO) - Biological Process for MIR4775 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4775 Gene

Drugs & Compounds for MIR4775 Gene

No Compound Related Data Available

Transcripts for MIR4775 Gene

mRNA/cDNA for MIR4775 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4775 Gene

No ASD Table

Relevant External Links for MIR4775 Gene

GeneLoc Exon Structure for
MIR4775
ECgene alternative splicing isoforms for
MIR4775

Expression for MIR4775 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4775 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4775 Gene:

MIR4775
genes like me logo Genes that share expression patterns with MIR4775: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4775 Gene

Orthologs for MIR4775 Gene

Evolution for MIR4775 Gene

ENSEMBL:
Gene Tree for MIR4775 (if available)
TreeFam:
Gene Tree for MIR4775 (if available)

No data available for Orthologs for MIR4775 Gene

Paralogs for MIR4775 Gene

No data available for Paralogs for MIR4775 Gene

Variants for MIR4775 Gene

Sequence variations from dbSNP and Humsavar for MIR4775 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1000259394 -- 207,753,045(+) GAAAA(-/AAAT)AATAA intron-variant, upstream-variant-2KB
rs1000592763 -- 207,754,481(+) TGCCA(A/C)CCAAC nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs1001717890 -- 207,753,478(+) GTAAC(-/TG)TGAAC intron-variant, upstream-variant-2KB
rs1001814363 -- 207,755,022(+) TAGCT(A/G)CTACA nc-transcript-variant, downstream-variant-500B, utr-variant-3-prime
rs1003032281 -- 207,753,120(+) AGACC(A/G)CTCAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4775 Gene

Variant ID Type Subtype PubMed ID
nsv3133 CNV insertion 18451855
nsv963769 CNV duplication 23825009

Relevant External Links for MIR4775 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4775

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4775 Gene

Disorders for MIR4775 Gene

Relevant External Links for MIR4775

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4775

No disorders were found for MIR4775 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4775 Gene

Publications for MIR4775 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4775 Gene

Sources for MIR4775 Gene

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