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Aliases for MIR4774 Gene

Subcategory (RNA class) for MIR4774 Gene


Quality Score for this RNA gene is


Aliases for MIR4774 Gene

  • MicroRNA 4774 2 3 5
  • Hsa-Mir-4774 3

External Ids for MIR4774 Gene

Previous GeneCards Identifiers for MIR4774 Gene

  • GC02U902454
  • GC02P169442

Summaries for MIR4774 Gene

Entrez Gene Summary for MIR4774 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4774 Gene

MIR4774 (MicroRNA 4774) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4774 Gene

Genomics for MIR4774 Gene

Regulatory Elements for MIR4774 Gene

Enhancers for MIR4774 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F168581 0.8 Ensembl ENCODE 0.8 +0.3 267 4.4 PKNOX1 ZMYM3 ZEB1 SCRT2 PRDM10 NFE2 NFE2L2 NR2F1 USF2 MAFG RNU6-766P CERS6 MIR4774 GC02M168607
GH02F168592 0.2 Ensembl 0.4 +9.6 9558 0.6 FOSL1 HMBOX1 MIR4774 GC02M168607 RNU6-766P
GH02F168590 0.5 Ensembl 0.4 +7.2 7158 0.2 ZNF146 HMBOX1 NFE2 EMSY ZNF7 MIR4774 GC02M168607 RNU6-766P
GH02F168572 0.6 Ensembl 0.4 -9.6 -9643 1.0 MAFG CEBPB EBF1 ZNF316 SMARCA4 SCRT2 FOS MAFK EMSY SPI1 MIR4774 GC02M168537
GH02F168594 0.7 Ensembl ENCODE 0.4 +12.0 11958 1.0 HLF TCF7 CEBPB EBF1 SPI1 STK39 GC02M168607 RNU6-766P MIR4774
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4774 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4774 Gene

168,582,943 bp from pter
168,583,018 bp from pter
76 bases
Plus strand

Genomic View for MIR4774 Gene

Genes around MIR4774 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4774 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4774 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4774 Gene

Proteins for MIR4774 Gene

Post-translational modifications for MIR4774 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4774 Gene

Domains & Families for MIR4774 Gene

Gene Families for MIR4774 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4774: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4774 Gene

Function for MIR4774 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4774 Gene

Localization for MIR4774 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4774 Gene

Pathways & Interactions for MIR4774 Gene

SuperPathways for MIR4774 Gene

No Data Available

Interacting Proteins for MIR4774 Gene

Gene Ontology (GO) - Biological Process for MIR4774 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4774 Gene

Transcripts for MIR4774 Gene

mRNA/cDNA for MIR4774 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4774 Gene

No ASD Table

Relevant External Links for MIR4774 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4774 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4774 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4774 Gene

Orthologs for MIR4774 Gene

Evolution for MIR4774 Gene

Gene Tree for MIR4774 (if available)
Gene Tree for MIR4774 (if available)

No data available for Orthologs for MIR4774 Gene

Paralogs for MIR4774 Gene

No data available for Paralogs for MIR4774 Gene

Variants for MIR4774 Gene

Sequence variations from dbSNP and Humsavar for MIR4774 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs113500467 -- 168,583,041(+) CAAAA(C/T)AATGC intron-variant, downstream-variant-500B
rs113886635 -- 168,581,404(+) TCGTT(C/T)TCTGT intron-variant, upstream-variant-2KB
rs113936204 -- 168,583,478(+) TTCAT(-/TTGC)TTTCT intron-variant, downstream-variant-500B
rs116166804 -- 168,581,859(+) GGAGA(A/C)TCTTG intron-variant, upstream-variant-2KB
rs12470825 -- 168,581,764(+) TTTGC(A/G)GGTGT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4774 Gene

Variant ID Type Subtype PubMed ID
dgv64n68 CNV gain 17160897
nsv428405 CNV loss 18775914

Relevant External Links for MIR4774 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4774 Gene

Disorders for MIR4774 Gene

Relevant External Links for MIR4774

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4774 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4774 Gene

Publications for MIR4774 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4774 Gene

Sources for MIR4774 Gene

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