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Aliases for MIR4773-1 Gene

Subcategory (RNA class) for MIR4773-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4773-1 Gene

  • MicroRNA 4773-1 2 3
  • MicroRNA 4773-2 5
  • Hsa-Mir-4773-1 3
  • MIR4773-2 5

External Ids for MIR4773-1 Gene

Previous GeneCards Identifiers for MIR4773-1 Gene

  • GC02U902429
  • GC02P152227

Summaries for MIR4773-1 Gene

Entrez Gene Summary for MIR4773-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4773-1 Gene

MIR4773-1 (MicroRNA 4773-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4773-1 Gene

Genomics for MIR4773-1 Gene

Regulatory Elements for MIR4773-1 Gene

Enhancers for MIR4773-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F151363 0.9 Ensembl ENCODE 0.8 -4.4 -4434 1.0 ATF1 CEBPB ATF2 RELA POLR2A ATF3 IKZF1 MLLT1 CREM RBM43 MIR4773-1 TNFAIP6
GH02F151356 0.6 ENCODE 0.4 -10.4 -10373 2.3 TBP PKNOX1 CEBPB FOS EP300 RFX5 TNFAIP6 MIR4773-1
GH02F151360 0.5 Ensembl 0.4 -8.2 -8234 0.2 ZNF316 CEBPB EMSY MAFK TNFAIP6 MIR4773-1
GH02F151361 0.2 ENCODE 0.4 -6.3 -6310 0.9 RBM43 NMI TNFAIP6 MIR4773-1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4773-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4773-1 Gene

Chromosome:
2
Start:
151,368,334 bp from pter
End:
151,368,411 bp from pter
Size:
78 bases
Orientation:
Plus strand

Genomic View for MIR4773-1 Gene

Genes around MIR4773-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4773-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4773-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4773-1 Gene

Proteins for MIR4773-1 Gene

Post-translational modifications for MIR4773-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4773-1 Gene

Domains & Families for MIR4773-1 Gene

Gene Families for MIR4773-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4773-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4773-1 Gene

Function for MIR4773-1 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4773-1 Gene

Localization for MIR4773-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4773-1 Gene

Pathways & Interactions for MIR4773-1 Gene

SuperPathways for MIR4773-1 Gene

No Data Available

Interacting Proteins for MIR4773-1 Gene

Gene Ontology (GO) - Biological Process for MIR4773-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4773-1 Gene

Transcripts for MIR4773-1 Gene

mRNA/cDNA for MIR4773-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4773-1 Gene

No ASD Table

Relevant External Links for MIR4773-1 Gene

GeneLoc Exon Structure for
MIR4773-1
ECgene alternative splicing isoforms for
MIR4773-1

Expression for MIR4773-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4773-1 Gene

genes like me logo Genes that share expression patterns with MIR4773-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4773-1 Gene

Orthologs for MIR4773-1 Gene

Evolution for MIR4773-1 Gene

ENSEMBL:
Gene Tree for MIR4773-1 (if available)
TreeFam:
Gene Tree for MIR4773-1 (if available)

No data available for Orthologs for MIR4773-1 Gene

Paralogs for MIR4773-1 Gene

No data available for Paralogs for MIR4773-1 Gene

Variants for MIR4773-1 Gene

Sequence variations from dbSNP and Humsavar for MIR4773-1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10180428 -- 151,366,967(+) TTCCA(C/G)CAGGA intron-variant, upstream-variant-2KB
rs10201647 -- 151,368,779(+) GAATT(C/T)ATGGG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs10432475 -- 151,368,426(+) TAGAC(A/G)TTAGA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs10432476 -- 151,368,574(+) ACATA(C/T)TGAAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs111303102 -- 151,366,847(+) ATTTT(A/T)TCCAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4773-1 Gene

Variant ID Type Subtype PubMed ID
nsv1012891 CNV gain 25217958
nsv2972 CNV insertion 18451855
nsv834418 CNV gain 17160897
esv34659 CNV loss 17911159
dgv4094n100 CNV gain 25217958

Relevant External Links for MIR4773-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4773-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4773-1 Gene

Disorders for MIR4773-1 Gene

Relevant External Links for MIR4773-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4773-1

No disorders were found for MIR4773-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4773-1 Gene

Publications for MIR4773-1 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4773-1 Gene

Sources for MIR4773-1 Gene

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