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Aliases for MIR4766 Gene

Subcategory (RNA class) for MIR4766 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4766 Gene

  • MicroRNA 4766 2 3 5
  • Hsa-Mir-4766 3
  • Mir-4766 3

External Ids for MIR4766 Gene

Previous GeneCards Identifiers for MIR4766 Gene

  • GC22U900802
  • GC22M041215

Summaries for MIR4766 Gene

Entrez Gene Summary for MIR4766 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4766 Gene

MIR4766 (MicroRNA 4766) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4766 Gene

Genomics for MIR4766 Gene

Regulatory Elements for MIR4766 Gene

Enhancers for MIR4766 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F040814 0.2 ENCODE 0.8 -0.2 -194 0.2 ATF1 PKNOX1 ARNT ELK1 GATA2 KLF13 NCOA1 CREB3 MBD2 MEF2D ST13 XPNPEP3 LOC101927257 MIR4766 SLC25A17
GH22F040816 0.6 ENCODE 0.8 -4.8 -4772 3.5 ARID4B SIN3A DMAP1 ZNF48 ZNF2 ZNF121 ZNF143 ZNF207 KLF7 KDM4B XPNPEP3 TEF LOC100313968 MIR4766 SLC25A17
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4766 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4766 Gene

Chromosome:
22
Start:
40,813,883 bp from pter
End:
40,813,958 bp from pter
Size:
76 bases
Orientation:
Minus strand

Genomic View for MIR4766 Gene

Genes around MIR4766 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4766 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4766 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4766 Gene

ORGUL Member Location for MIR4766 Gene

ORGUL Member Location for MIR4766 gene

Proteins for MIR4766 Gene

Post-translational modifications for MIR4766 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4766 Gene

Domains & Families for MIR4766 Gene

Gene Families for MIR4766 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4766: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4766 Gene

Function for MIR4766 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4766 Gene

Localization for MIR4766 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4766 Gene

Pathways & Interactions for MIR4766 Gene

SuperPathways for MIR4766 Gene

No Data Available

Interacting Proteins for MIR4766 Gene

Gene Ontology (GO) - Biological Process for MIR4766 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4766 Gene

Transcripts for MIR4766 Gene

mRNA/cDNA for MIR4766 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4766 Gene

No ASD Table

Relevant External Links for MIR4766 Gene

GeneLoc Exon Structure for
MIR4766
ECgene alternative splicing isoforms for
MIR4766

Expression for MIR4766 Gene

mRNA expression in normal human tissues for MIR4766 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4766 Gene:

MIR4766
genes like me logo Genes that share expression patterns with MIR4766: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4766 Gene

Orthologs for MIR4766 Gene

Evolution for MIR4766 Gene

ENSEMBL:
Gene Tree for MIR4766 (if available)
TreeFam:
Gene Tree for MIR4766 (if available)

No data available for Orthologs for MIR4766 Gene

Paralogs for MIR4766 Gene

No data available for Paralogs for MIR4766 Gene

Variants for MIR4766 Gene

Sequence variations from dbSNP and Humsavar for MIR4766 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs10527651 -- 40,814,777(+) TATAT(-/ATATATATATATAT)TGTTG intron-variant, upstream-variant-2KB
rs111887976 -- 40,814,755(+) GCAGA(-/ATATATATATATAT)ATATA intron-variant, upstream-variant-2KB
rs112906434 -- 40,813,656(+) GAGGC(G/T)GAGCT intron-variant, downstream-variant-500B
rs113014804 -- 40,813,501(+) CCACC(A/G)CACTC intron-variant, downstream-variant-500B
rs116921591 -- 40,814,614(+) GAAAA(G/T)ACACA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4766 Gene

Variant ID Type Subtype PubMed ID
nsv834206 CNV gain 17160897

Relevant External Links for MIR4766 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4766

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4766 Gene

Disorders for MIR4766 Gene

Relevant External Links for MIR4766

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4766

No disorders were found for MIR4766 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4766 Gene

Publications for MIR4766 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4766 Gene

Sources for MIR4766 Gene

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