Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR4762 Gene

Subcategory (RNA class) for MIR4762 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4762 Gene

  • MicroRNA 4762 2 3 5
  • Hsa-Mir-4762 3

External Ids for MIR4762 Gene

Previous GeneCards Identifiers for MIR4762 Gene

  • GC22U900798
  • GC22P046159

Summaries for MIR4762 Gene

Entrez Gene Summary for MIR4762 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4762 Gene

MIR4762 (MicroRNA 4762) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4762 Gene

Genomics for MIR4762 Gene

Regulatory Elements for MIR4762 Gene

Enhancers for MIR4762 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F045756 1.2 Ensembl ENCODE 0.8 -3.3 -3319 0.7 CTCF KLF1 PKNOX1 MAZ TEAD4 SP2 ZIC2 ZFHX2 GLIS2 KLF9 ATXN10 MIR4762 PIR51279
GH22F045762 0.2 ENCODE 0.8 +3.0 3023 2.1 SAP130 HLF ARID4B ZIC2 RARA ZNF341 SCRT2 HNF4G FOS ATXN10 MIR4762 GC22M045793
GH22F045768 0.6 ENCODE 0.4 +8.0 8008 0.5 POLR2A MIR4762 GC22M045793
GH22F045774 0.2 ENCODE 0.3 +16.1 16066 3.2 TBL1XR1 DMAP1 ZBTB40 YY1 SCRT2 CREM CEBPB TBX21 SP1 RAD51 ATXN10 LINC01589 GC22M045793 MIR4762
GH22F045784 0.8 Ensembl ENCODE 0.3 +24.7 24748 1.9 HDAC1 LEF1 CBX3 TAL1 MAX CEBPG RAD21 CHAMP1 YY1 GATA2 GC22M045793 MIR4762
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4762 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4762 Gene

Chromosome:
22
Start:
45,760,524 bp from pter
End:
45,760,598 bp from pter
Size:
75 bases
Orientation:
Plus strand

Genomic View for MIR4762 Gene

Genes around MIR4762 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4762 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4762 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4762 Gene

Proteins for MIR4762 Gene

Post-translational modifications for MIR4762 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4762 Gene

Domains & Families for MIR4762 Gene

Gene Families for MIR4762 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4762: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4762 Gene

Function for MIR4762 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4762 Gene

Localization for MIR4762 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4762 Gene

Pathways & Interactions for MIR4762 Gene

SuperPathways for MIR4762 Gene

No Data Available

Interacting Proteins for MIR4762 Gene

Gene Ontology (GO) - Biological Process for MIR4762 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4762 Gene

Transcripts for MIR4762 Gene

mRNA/cDNA for MIR4762 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4762 Gene

No ASD Table

Relevant External Links for MIR4762 Gene

GeneLoc Exon Structure for
MIR4762
ECgene alternative splicing isoforms for
MIR4762

Expression for MIR4762 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4762 Gene:

MIR4762
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4762 Gene

Orthologs for MIR4762 Gene

Evolution for MIR4762 Gene

ENSEMBL:
Gene Tree for MIR4762 (if available)
TreeFam:
Gene Tree for MIR4762 (if available)

No data available for Orthologs for MIR4762 Gene

Paralogs for MIR4762 Gene

No data available for Paralogs for MIR4762 Gene

Variants for MIR4762 Gene

Sequence variations from dbSNP and Humsavar for MIR4762 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs111656853 -- 45,760,524(+) TATTT(C/G)TGATA intron-variant, nc-transcript-variant
rs111989297 -- 45,759,760(+) CTGCC(A/G)GCATG intron-variant, upstream-variant-2KB
rs113845668 -- 45,760,446(+) GCAGT(A/C)CTTGT intron-variant, upstream-variant-2KB
rs117788150 -- 45,760,329(+) ATTCA(C/T)GTACC intron-variant, upstream-variant-2KB
rs11912739 -- 45,759,929(+) CCTCT(A/G)TCCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4762 Gene

Variant ID Type Subtype PubMed ID
dgv2469n106 OTHER inversion 24896259
dgv73n68 CNV gain 17160897
nsv1064179 CNV loss 25217958
nsv1066204 CNV gain 25217958
nsv1152661 OTHER inversion 26484159
nsv1160779 CNV duplication 26073780

Relevant External Links for MIR4762 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4762

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4762 Gene

Disorders for MIR4762 Gene

Relevant External Links for MIR4762

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4762

No disorders were found for MIR4762 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4762 Gene

Publications for MIR4762 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4762 Gene

Sources for MIR4762 Gene

Content
Loading form....