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Aliases for MIR4760 Gene

Subcategory (RNA class) for MIR4760 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4760 Gene

  • MicroRNA 4760 2 3 5
  • Hsa-Mir-4760 3

External Ids for MIR4760 Gene

Previous GeneCards Identifiers for MIR4760 Gene

  • GC21U900447
  • GC21M041587

Summaries for MIR4760 Gene

Entrez Gene Summary for MIR4760 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4760 Gene

MIR4760 (MicroRNA 4760) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4760 Gene

Genomics for MIR4760 Gene

Regulatory Elements for MIR4760 Gene

Enhancers for MIR4760 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH21G040185 0.8 ENCODE 0.3 +25.6 25566 2.4 SOX13 BACH1 BMI1 ZNF697 RARA ARID3A GATA2 RELB CREM GATAD2A DSCAM MIR4760 GC21P040155
GH21G040176 0.6 ENCODE 0.3 +35.6 35583 0.2 ZNF263 RFX1 POLR2A REST RAD21 EP300 DSCAM GC21P040155 MIR4760
GH21G040330 1.1 dbSUPER 0.1 -124.7 -124692 13.4 HDGF PKNOX1 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 FEZF1 ZBTB7B HMGN1 DSCAM-AS1 MIR4760
GH21G040165 0.5 ENCODE 0.2 +46.5 46463 0.3 BCL6B BCL6 MAFK GC21P040155 MIR4760
GH21G040378 1 dbSUPER 0.1 -167.4 -167411 2.1 FOXA2 PKNOX1 ARID4B SIN3A ZNF207 ZNF263 SP5 ZNF488 TSHZ1 NFIL3 DSCAM-AS1 MIR4760
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4760 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4760 Gene

Chromosome:
21
Start:
40,212,352 bp from pter
End:
40,212,431 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR4760 Gene

Genes around MIR4760 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4760 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4760 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4760 Gene

Proteins for MIR4760 Gene

Post-translational modifications for MIR4760 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4760 Gene

Domains & Families for MIR4760 Gene

Gene Families for MIR4760 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4760: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4760 Gene

Function for MIR4760 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4760 Gene

Localization for MIR4760 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4760 Gene

Pathways & Interactions for MIR4760 Gene

SuperPathways for MIR4760 Gene

No Data Available

Interacting Proteins for MIR4760 Gene

Gene Ontology (GO) - Biological Process for MIR4760 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4760 Gene

Drugs & Compounds for MIR4760 Gene

No Compound Related Data Available

Transcripts for MIR4760 Gene

mRNA/cDNA for MIR4760 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4760 Gene

No ASD Table

Relevant External Links for MIR4760 Gene

GeneLoc Exon Structure for
MIR4760
ECgene alternative splicing isoforms for
MIR4760

Expression for MIR4760 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4760 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4760 Gene:

MIR4760
genes like me logo Genes that share expression patterns with MIR4760: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4760 Gene

Orthologs for MIR4760 Gene

Evolution for MIR4760 Gene

ENSEMBL:
Gene Tree for MIR4760 (if available)
TreeFam:
Gene Tree for MIR4760 (if available)

No data available for Orthologs for MIR4760 Gene

Paralogs for MIR4760 Gene

No data available for Paralogs for MIR4760 Gene

Variants for MIR4760 Gene

Sequence variations from dbSNP and Humsavar for MIR4760 Gene

SNP ID Clin Chr 21 pos Sequence Context AA Info Type
rs1000463683 -- 40,212,181(+) GCCAG(G/T)CTGAT intron-variant, downstream-variant-500B
rs1001138146 -- 40,211,991(+) GTGGG(A/G)GGGAG intron-variant, downstream-variant-500B
rs1001590482 -- 40,212,560(+) TCTCA(C/G)ACCAA intron-variant, upstream-variant-2KB
rs1002020612 -- 40,212,234(+) AAGTG(C/G)TGGGA intron-variant, downstream-variant-500B
rs1003959371 -- 40,212,342(+) ACCTT(-/GA)GAGGC intron-variant, downstream-variant-500B

Relevant External Links for MIR4760 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4760

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4760 Gene

Disorders for MIR4760 Gene

Relevant External Links for MIR4760

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4760

No disorders were found for MIR4760 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4760 Gene

Publications for MIR4760 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4760 Gene

Sources for MIR4760 Gene

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