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Aliases for MIR4757 Gene

Subcategory (RNA class) for MIR4757 Gene


Quality Score for this RNA gene is


Aliases for MIR4757 Gene

  • MicroRNA 4757 2 3 5
  • Hsa-Mir-4757 3

External Ids for MIR4757 Gene

Previous GeneCards Identifiers for MIR4757 Gene

  • GC02U902455
  • GC02P019551

Summaries for MIR4757 Gene

Entrez Gene Summary for MIR4757 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4757 Gene

MIR4757 (MicroRNA 4757) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4757 Gene

Genomics for MIR4757 Gene

Regulatory Elements for MIR4757 Gene

Enhancers for MIR4757 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F019346 1.3 FANTOM5 ENCODE 0.8 +0.8 755 4.4 HDGF MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 MIR4757 GC02P019358
GH02F019354 0.5 ENCODE 0.4 +8.6 8562 5.1 CTCF PKNOX1 SUZ12 SIN3A E2F1 GATA3 POLR2A RCOR1 ZNF652 MAFK SDC1 GC02P019358 MIR4757
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4757 on UCSC Golden Path with GeneCards custom track

Promoters for MIR4757 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000121665 -429 1601 HDGF MLX ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF143 SP3 SP5

Genomic Location for MIR4757 Gene

19,348,429 bp from pter
19,348,505 bp from pter
77 bases
Plus strand

Genomic View for MIR4757 Gene

Genes around MIR4757 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4757 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4757 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4757 Gene

Proteins for MIR4757 Gene

Post-translational modifications for MIR4757 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4757 Gene

Domains & Families for MIR4757 Gene

Gene Families for MIR4757 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4757: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4757 Gene

Function for MIR4757 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4757 Gene

Localization for MIR4757 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4757 Gene

Pathways & Interactions for MIR4757 Gene

SuperPathways for MIR4757 Gene

No Data Available

Interacting Proteins for MIR4757 Gene

Gene Ontology (GO) - Biological Process for MIR4757 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4757 Gene

Transcripts for MIR4757 Gene

mRNA/cDNA for MIR4757 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4757 Gene

No ASD Table

Relevant External Links for MIR4757 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4757 Gene

mRNA expression in normal human tissues for MIR4757 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4757 Gene:

genes like me logo Genes that share expression patterns with MIR4757: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4757 Gene

Orthologs for MIR4757 Gene

Evolution for MIR4757 Gene

Gene Tree for MIR4757 (if available)
Gene Tree for MIR4757 (if available)

No data available for Orthologs for MIR4757 Gene

Paralogs for MIR4757 Gene

No data available for Paralogs for MIR4757 Gene

Variants for MIR4757 Gene

Sequence variations from dbSNP and Humsavar for MIR4757 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs114666149 -- 19,348,218(+) GGCAC(C/G)GCCCT upstream-variant-2KB
rs114689414 -- 19,347,700(+) AGAGA(A/G)GCTGC upstream-variant-2KB
rs115155996 -- 19,348,030(+) GCCTG(C/T)GAGTT upstream-variant-2KB
rs12710706 -- 19,347,034(+) CCCTA(C/T)GTCAT upstream-variant-2KB
rs13427470 -- 19,348,622(+) GCATC(A/C)CATTG downstream-variant-500B

Relevant External Links for MIR4757 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4757 Gene

Disorders for MIR4757 Gene

Relevant External Links for MIR4757

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4757 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4757 Gene

Publications for MIR4757 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4757 Gene

Sources for MIR4757 Gene

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