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Aliases for MIR4757 Gene

Subcategory (RNA class) for MIR4757 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4757 Gene

  • MicroRNA 4757 2 3 5
  • Hsa-Mir-4757 3

External Ids for MIR4757 Gene

Previous GeneCards Identifiers for MIR4757 Gene

  • GC02U902455
  • GC02P019551

Summaries for MIR4757 Gene

Entrez Gene Summary for MIR4757 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4757 Gene

MIR4757 (MicroRNA 4757) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4757 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4757 Gene

Genomics for MIR4757 Gene

GeneHancer (GH) Regulatory Elements for MIR4757 Gene

Promoters and enhancers for MIR4757 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I019346 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 550.8 +0.8 754 4.4 HDGF SMAD1 MLX ARNT ARID4B SIN3A DMAP1 IRF4 YY1 SLC30A9 MIR4757 GC02P019358
GH02I019354 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE dbSUPER 0.4 +8.5 8473 5.2 ZBTB6 SUZ12 SIN3A ZNF335 E2F1 CTBP1 GATA3 POLR2A RCOR1 EZH2 GC02P019358 OSR1 SDC1 MIR4757
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4757 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4757 Gene

Genomic Locations for MIR4757 Gene
chr2:19,348,429-19,348,505
(GRCh38/hg38)
Size:
77 bases
Orientation:
Plus strand
chr2:19,548,190-19,548,266
(GRCh37/hg19)

Genomic View for MIR4757 Gene

Genes around MIR4757 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4757 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4757 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4757 Gene

Proteins for MIR4757 Gene

Post-translational modifications for MIR4757 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4757 Gene

Domains & Families for MIR4757 Gene

Gene Families for MIR4757 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4757: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4757 Gene

Function for MIR4757 Gene

Phenotypes From GWAS Catalog for MIR4757 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4757 Gene

Localization for MIR4757 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4757 Gene

Pathways & Interactions for MIR4757 Gene

SuperPathways for MIR4757 Gene

No Data Available

Interacting Proteins for MIR4757 Gene

Gene Ontology (GO) - Biological Process for MIR4757 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4757 Gene

Drugs & Compounds for MIR4757 Gene

No Compound Related Data Available

Transcripts for MIR4757 Gene

mRNA/cDNA for MIR4757 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4757 Gene

No ASD Table

Relevant External Links for MIR4757 Gene

GeneLoc Exon Structure for
MIR4757
ECgene alternative splicing isoforms for
MIR4757

Expression for MIR4757 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4757 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4757 Gene:

MIR4757
genes like me logo Genes that share expression patterns with MIR4757: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4757 Gene

Orthologs for MIR4757 Gene

Evolution for MIR4757 Gene

ENSEMBL:
Gene Tree for MIR4757 (if available)
TreeFam:
Gene Tree for MIR4757 (if available)

No data available for Orthologs for MIR4757 Gene

Paralogs for MIR4757 Gene

No data available for Paralogs for MIR4757 Gene

Variants for MIR4757 Gene

Sequence variations from dbSNP and Humsavar for MIR4757 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000115812 -- 19,348,432(+) C/G non_coding_transcript_variant
rs1001234363 -- 19,347,772(+) G/A upstream_transcript_variant
rs1001976542 -- 19,348,339(+) T/G upstream_transcript_variant
rs1003362977 -- 19,347,565(+) C/T upstream_transcript_variant
rs1004518310 -- 19,347,506(+) G/A upstream_transcript_variant

Additional Variant Information for MIR4757 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4757

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4757 Gene

Disorders for MIR4757 Gene

Additional Disease Information for MIR4757

No disorders were found for MIR4757 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4757 Gene

Publications for MIR4757 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4757 Gene

Sources for MIR4757 Gene

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