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Aliases for MIR4756 Gene

Subcategory (RNA class) for MIR4756 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4756 Gene

  • MicroRNA 4756 2 3 5
  • Hsa-Mir-4756 3

External Ids for MIR4756 Gene

Previous GeneCards Identifiers for MIR4756 Gene

  • GC20U900698
  • GC20M052687

Summaries for MIR4756 Gene

Entrez Gene Summary for MIR4756 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4756 Gene

MIR4756 (MicroRNA 4756) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4756 Gene

Genomics for MIR4756 Gene

Regulatory Elements for MIR4756 Gene

Enhancers for MIR4756 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH20G054065 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -0.1 -61 6.0 PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF143 FOS DEK MXD4 BCAS1 PFDN4 MIR4756
GH20G054063 0.8 ENCODE 0.7 +4.3 4257 1.4 PKNOX1 BACH1 ZMYM3 NFXL1 EBF1 RELA ARID3A GATA2 RELB IKZF2 BCAS1 CYP24A1 MIR4756 GC20M054012
GH20G054062 0.7 ENCODE 0.4 +5.5 5539 0.2 CTCF PKNOX1 ZNF654 TRIM22 REST EP300 RAD21 PBX2 SMC3 ZNF143 CYP24A1 BCAS1 MIR4756 GC20M054012
GH20G054044 0.9 ENCODE 0.3 +24.1 24109 0.2 HDAC1 PKNOX1 ATF1 CBX3 TBL1XR1 CHAMP1 TCF12 GATA2 ETV6 FOS MIR4756 GC20M054012
GH20G054017 1 Ensembl ENCODE 0.2 +50.6 50633 1.7 TBP MXI1 BMI1 NFXL1 ZBTB40 CBX5 ETV6 RELB IKZF2 BCLAF1 GC20M054012 MIR4756
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4756 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4756 Gene

Chromosome:
20
Start:
54,068,408 bp from pter
End:
54,068,485 bp from pter
Size:
78 bases
Orientation:
Minus strand

Genomic View for MIR4756 Gene

Genes around MIR4756 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4756 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4756 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4756 Gene

Proteins for MIR4756 Gene

Post-translational modifications for MIR4756 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4756 Gene

Domains & Families for MIR4756 Gene

Gene Families for MIR4756 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4756: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4756 Gene

Function for MIR4756 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4756 Gene

Localization for MIR4756 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4756 Gene

Pathways & Interactions for MIR4756 Gene

SuperPathways for MIR4756 Gene

No Data Available

Interacting Proteins for MIR4756 Gene

Gene Ontology (GO) - Biological Process for MIR4756 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4756 Gene

Drugs & Compounds for MIR4756 Gene

No Compound Related Data Available

Transcripts for MIR4756 Gene

mRNA/cDNA for MIR4756 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4756 Gene

No ASD Table

Relevant External Links for MIR4756 Gene

GeneLoc Exon Structure for
MIR4756
ECgene alternative splicing isoforms for
MIR4756

Expression for MIR4756 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4756 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4756 Gene:

MIR4756
genes like me logo Genes that share expression patterns with MIR4756: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4756 Gene

Orthologs for MIR4756 Gene

Evolution for MIR4756 Gene

ENSEMBL:
Gene Tree for MIR4756 (if available)
TreeFam:
Gene Tree for MIR4756 (if available)

No data available for Orthologs for MIR4756 Gene

Paralogs for MIR4756 Gene

No data available for Paralogs for MIR4756 Gene

Variants for MIR4756 Gene

Sequence variations from dbSNP and Humsavar for MIR4756 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs1001920670 -- 54,069,839(+) CGCAC(C/T)CGCAT intron-variant, upstream-variant-2KB
rs1002927370 -- 54,068,660(+) GGCAC(C/T)TTACT intron-variant, upstream-variant-2KB
rs1003713602 -- 54,069,784(+) GCACC(C/T)AGCCA intron-variant, upstream-variant-2KB
rs1006160636 -- 54,070,118(+) GTGAC(C/T)TCTCC intron-variant, upstream-variant-2KB
rs1007861757 -- 54,068,093(+) TACAA(A/G)GGGAC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4756 Gene

Variant ID Type Subtype PubMed ID
dgv1254e212 CNV loss 25503493
esv2758801 CNV loss 17122850
esv34060 CNV loss 18971310
nsv586224 CNV gain 21841781

Relevant External Links for MIR4756 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4756

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4756 Gene

Disorders for MIR4756 Gene

Relevant External Links for MIR4756

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4756

No disorders were found for MIR4756 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4756 Gene

Publications for MIR4756 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4756 Gene

Sources for MIR4756 Gene

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