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Aliases for MIR4753 Gene

Subcategory (RNA class) for MIR4753 Gene


Quality Score for this RNA gene is


Aliases for MIR4753 Gene

  • MicroRNA 4753 2 3 5
  • Hsa-Mir-4753 3
  • Mir-4753 3

External Ids for MIR4753 Gene

Previous GeneCards Identifiers for MIR4753 Gene

  • GC01U903288
  • GC01M235357

Summaries for MIR4753 Gene

Entrez Gene Summary for MIR4753 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4753 Gene

MIR4753 (MicroRNA 4753) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4753 Gene

Genomics for MIR4753 Gene

Regulatory Elements for MIR4753 Gene

Enhancers for MIR4753 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F235199 0.2 ENCODE 0.4 -9.6 -9644 0.9 ZNF121 CTCF ZNF654 TEAD4 ZBTB33 PRDM1 RAD21 SNORA14B TOMM20 ARID4B MIR4753 GC01P235225
GH01F235206 0.6 ENCODE 0.3 -16.8 -16825 0.2 BCOR ARNT ZNF384 GATA2 NCOR1 SIRT6 TRIM24 KLF8 DNMT1 SMARCA5 SNORA14B TOMM20 ARID4B GGPS1 MIR4753 GC01P235225
GH01F235207 0.6 ENCODE 0.3 -17.3 -17265 0.2 HDAC1 ESRRA NRF1 ZEB2 NFE2 KDM1A HES1 SNORA14B TOMM20 GGPS1 ARID4B MIR4753 GC01P235225
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4753 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4753 Gene

235,190,034 bp from pter
235,190,116 bp from pter
83 bases
Minus strand

Genomic View for MIR4753 Gene

Genes around MIR4753 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4753 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4753 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4753 Gene

ORGUL Member Location for MIR4753 Gene

ORGUL Member Location for MIR4753 gene

Proteins for MIR4753 Gene

Post-translational modifications for MIR4753 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4753 Gene

Domains & Families for MIR4753 Gene

Gene Families for MIR4753 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4753: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4753 Gene

Function for MIR4753 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4753 Gene

Localization for MIR4753 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4753 Gene

Pathways & Interactions for MIR4753 Gene

SuperPathways for MIR4753 Gene

No Data Available

Interacting Proteins for MIR4753 Gene

Gene Ontology (GO) - Biological Process for MIR4753 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4753 Gene

Transcripts for MIR4753 Gene

mRNA/cDNA for MIR4753 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4753 Gene

No ASD Table

Relevant External Links for MIR4753 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4753 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4753 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4753 Gene:

genes like me logo Genes that share expression patterns with MIR4753: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4753 Gene

Orthologs for MIR4753 Gene

Evolution for MIR4753 Gene

Gene Tree for MIR4753 (if available)
Gene Tree for MIR4753 (if available)

No data available for Orthologs for MIR4753 Gene

Paralogs for MIR4753 Gene

No data available for Paralogs for MIR4753 Gene

Variants for MIR4753 Gene

Sequence variations from dbSNP and Humsavar for MIR4753 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10157739 -- 235,191,240(+) TGTCA(C/G)ATATT intron-variant, upstream-variant-2KB
rs112007686 -- 235,191,930(+) AAAAT(-/T)AGCCT intron-variant, upstream-variant-2KB
rs114021429 -- 235,191,851(+) ATGGA(G/T)TGGAT intron-variant, upstream-variant-2KB
rs11409901 -- 235,190,460(+) AAAAA(-/A)GATTC intron-variant, upstream-variant-2KB
rs139862994 -- 235,191,599(+) TTTAT(C/G)AGAAC intron-variant, upstream-variant-2KB

Relevant External Links for MIR4753 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4753 Gene

Disorders for MIR4753 Gene

Relevant External Links for MIR4753

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4753 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4753 Gene

Publications for MIR4753 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4753 Gene

Sources for MIR4753 Gene

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