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Aliases for MIR4753 Gene

Subcategory (RNA class) for MIR4753 Gene


Quality Score for this RNA gene is


Aliases for MIR4753 Gene

  • MicroRNA 4753 2 3 5
  • Hsa-Mir-4753 3
  • Mir-4753 3

External Ids for MIR4753 Gene

Previous GeneCards Identifiers for MIR4753 Gene

  • GC01U903288
  • GC01M235357

Summaries for MIR4753 Gene

Entrez Gene Summary for MIR4753 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4753 Gene

MIR4753 (MicroRNA 4753) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4753 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4753 Gene

Genomics for MIR4753 Gene

Regulatory Elements for MIR4753 Gene

Enhancers for MIR4753 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H235206 0.8 ENCODE 0.4 -16.8 -16825 0 BCOR ARNT FOSL1 CC2D1A GATA2 NCOR1 ZNF350 SIRT6 TRIM24 RUNX3 ARID4B SNORA14B TOMM20 GGPS1 RPS21P1 GC01P235225 MIR4753
GH01H235207 0.6 ENCODE 0.4 -17.3 -17265 0 HDAC1 NRF1 MLLT1 KDM1A NFE2 ZEB2 RUNX3 SNORA14B TOMM20 GGPS1 ARID4B GC01P235225 MIR4753
GH01H235199 0.5 ENCODE 0.4 -9.6 -9644 0 CTCF ZNF654 PRDM1 RAD21 SNORA14B TOMM20 ARID4B MIR4753 GC01P235225
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4753 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4753 Gene

235,190,034 bp from pter
235,190,116 bp from pter
83 bases
Minus strand

Genomic View for MIR4753 Gene

Genes around MIR4753 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4753 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4753 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4753 Gene

ORGUL Member Location for MIR4753 Gene

ORGUL Member Location for MIR4753 gene

Proteins for MIR4753 Gene

Post-translational modifications for MIR4753 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4753 Gene

Domains & Families for MIR4753 Gene

Gene Families for MIR4753 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4753: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4753 Gene

Function for MIR4753 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4753
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4753 Gene

Localization for MIR4753 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4753 Gene

Pathways & Interactions for MIR4753 Gene

SuperPathways for MIR4753 Gene

No Data Available

Interacting Proteins for MIR4753 Gene

Gene Ontology (GO) - Biological Process for MIR4753 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4753 Gene

Drugs & Compounds for MIR4753 Gene

No Compound Related Data Available

Transcripts for MIR4753 Gene

mRNA/cDNA for MIR4753 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR4753
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4753 Gene

No ASD Table

Relevant External Links for MIR4753 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4753 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4753 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4753 Gene:

genes like me logo Genes that share expression patterns with MIR4753: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4753 Gene

Orthologs for MIR4753 Gene

Evolution for MIR4753 Gene

Gene Tree for MIR4753 (if available)
Gene Tree for MIR4753 (if available)

No data available for Orthologs for MIR4753 Gene

Paralogs for MIR4753 Gene

No data available for Paralogs for MIR4753 Gene

Variants for MIR4753 Gene

Sequence variations from dbSNP and Humsavar for MIR4753 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000987000 -- 235,191,525(+) TGCTG(A/G)GATTA intron-variant, upstream-variant-2KB
rs1000991374 -- 235,189,754(+) AAATT(G/T)GGCAG intron-variant, downstream-variant-500B
rs1001866034 -- 235,191,993(+) AGGTC(A/G)CTTGA intron-variant, upstream-variant-2KB
rs1004111823 -- 235,191,999(+) CTTGA(A/G)CCCAG intron-variant, upstream-variant-2KB
rs1004887186 -- 235,190,815(+) AACTA(C/T)ATTAA intron-variant, upstream-variant-2KB

Relevant External Links for MIR4753 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR4753 Gene

Disorders for MIR4753 Gene

Relevant External Links for MIR4753

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4753 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4753 Gene

Publications for MIR4753 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4753 Gene

Sources for MIR4753 Gene

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