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Aliases for MIR4751 Gene

Subcategory (RNA class) for MIR4751 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4751 Gene

  • MicroRNA 4751 2 3 5
  • Hsa-Mir-4751 3

External Ids for MIR4751 Gene

Previous GeneCards Identifiers for MIR4751 Gene

  • GC19U901550
  • GC19P050438

Summaries for MIR4751 Gene

Entrez Gene Summary for MIR4751 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4751 Gene

MIR4751 (MicroRNA 4751) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Circadian rythm related genes and Myometrial Relaxation and Contraction Pathways.

Additional gene information for MIR4751 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4751 Gene

Genomics for MIR4751 Gene

GeneHancer (GH) Regulatory Elements for MIR4751 Gene

Promoters and enhancers for MIR4751 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I049932 Enhancer 0.7 Ensembl ENCODE 550.8 -0.1 -53 0.5 SMARCA5 CCNT2 POLR2B TARDBP ZBTB33 MIR4751 NUP62 ATF5 ENSG00000269179
GH19I049933 Enhancer 0.6 ENCODE 550.8 -0.7 -695 0.1 HDGF PKNOX1 AFF1 ARNT NCOA1 TSC22D4 TCF12 IRF9 POLR2B TARDBP MIR4751 ATF5 NUP62 ENSG00000269179
GH19I049934 Enhancer 0.6 ENCODE 550.8 +0.7 653 0.1 HDAC1 BACH1 ZEB2 ZNF148 POLR2B CBX1 CTBP1 POLR2A E2F8 TARDBP MIR4751 NUP62 ATF5 GC19M049951 ENSG00000221125 ENSG00000269179
GH19I049937 Enhancer 1.1 Ensembl ENCODE 0.4 +5.2 5185 1.8 HDAC1 ELF3 RB1 ARID4B SIN3A RAD21 ZNF335 GLIS2 ARID2 EGR1 MIR4751 ENSG00000221125 GC19M049951 ENSG00000269179
GH19I049941 Enhancer 0.6 ENCODE 0.4 +8.5 8486 0.8 MEIS2 PKNOX1 NR2F1 USF2 MNT REST DPF2 MITF FOSL1 RAD51 ASPDH MIR4751 GC19M049951 ENSG00000221125 ENSG00000269179
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR4751 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4751 Gene

Genomic Locations for MIR4751 Gene
chr19:49,933,064-49,933,137
(GRCh38/hg38)
Size:
74 bases
Orientation:
Plus strand
chr19:50,436,321-50,436,394
(GRCh37/hg19)

Genomic View for MIR4751 Gene

Genes around MIR4751 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4751 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4751 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4751 Gene

Proteins for MIR4751 Gene

Post-translational modifications for MIR4751 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4751 Gene

Domains & Families for MIR4751 Gene

Gene Families for MIR4751 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4751: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4751 Gene

Function for MIR4751 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4751 Gene

Localization for MIR4751 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4751 Gene

Pathways & Interactions for MIR4751 Gene

genes like me logo Genes that share pathways with MIR4751: view

Pathways by source for MIR4751 Gene

Interacting Proteins for MIR4751 Gene

Gene Ontology (GO) - Biological Process for MIR4751 Gene

None

No data available for SIGNOR curated interactions for MIR4751 Gene

Drugs & Compounds for MIR4751 Gene

No Compound Related Data Available

Transcripts for MIR4751 Gene

mRNA/cDNA for MIR4751 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4751 Gene

No ASD Table

Relevant External Links for MIR4751 Gene

GeneLoc Exon Structure for
MIR4751
ECgene alternative splicing isoforms for
MIR4751

Expression for MIR4751 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4751 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4751 Gene:

MIR4751
genes like me logo Genes that share expression patterns with MIR4751: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4751 Gene

Orthologs for MIR4751 Gene

Evolution for MIR4751 Gene

ENSEMBL:
Gene Tree for MIR4751 (if available)
TreeFam:
Gene Tree for MIR4751 (if available)

No data available for Orthologs for MIR4751 Gene

Paralogs for MIR4751 Gene

No data available for Paralogs for MIR4751 Gene

Variants for MIR4751 Gene

Sequence variations from dbSNP and Humsavar for MIR4751 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000223412 -- 49,932,306(+) GTTGTTTT/GTTGTTTTGTTGTTTT upstream_transcript_variant
rs1001818136 -- 49,931,615(+) G/A upstream_transcript_variant
rs1003736231 -- 49,933,193(+) G/T downstream_transcript_variant
rs1005322785 -- 49,931,748(+) A/G upstream_transcript_variant
rs1005681923 -- 49,931,991(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR4751 Gene

Variant ID Type Subtype PubMed ID
dgv53n68 CNV loss 17160897
dgv54n68 CNV loss 17160897
esv3644630 CNV gain 21293372
nsv1058623 CNV gain 25217958
nsv1065648 CNV gain 25217958
nsv1140251 OTHER inversion 24896259
nsv458720 CNV gain 19166990
nsv579910 CNV gain 21841781
nsv579911 CNV gain 21841781
nsv7309 OTHER inversion 18451855
nsv953600 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Additional Variant Information for MIR4751 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4751

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4751 Gene

Disorders for MIR4751 Gene

Additional Disease Information for MIR4751

No disorders were found for MIR4751 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4751 Gene

Publications for MIR4751 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR4751 Gene

Sources for MIR4751 Gene

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