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Aliases for MIR4749 Gene

Subcategory (RNA class) for MIR4749 Gene


Quality Score for this RNA gene is


Aliases for MIR4749 Gene

  • MicroRNA 4749 2 3 5
  • Hsa-Mir-4749 3
  • Mir-4749 3

External Ids for MIR4749 Gene

Previous GeneCards Identifiers for MIR4749 Gene

  • GC19U901546
  • GC19P050361

Summaries for MIR4749 Gene

Entrez Gene Summary for MIR4749 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4749 Gene

MIR4749 (MicroRNA 4749) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4749 Gene

Genomics for MIR4749 Gene

Genomic Location for MIR4749 Gene

49,854,591 bp from pter
49,854,651 bp from pter
61 bases
Plus strand

Genomic View for MIR4749 Gene

Genes around MIR4749 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4749 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4749 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4749 Gene

No data available for Regulatory Elements for MIR4749 Gene

Proteins for MIR4749 Gene

Post-translational modifications for MIR4749 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4749 Gene

Domains & Families for MIR4749 Gene

Gene Families for MIR4749 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4749: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4749 Gene

Function for MIR4749 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4749 Gene

Localization for MIR4749 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4749 Gene

Pathways & Interactions for MIR4749 Gene

SuperPathways for MIR4749 Gene

No Data Available

Interacting Proteins for MIR4749 Gene

Gene Ontology (GO) - Biological Process for MIR4749 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR4749 Gene

Transcripts for MIR4749 Gene

mRNA/cDNA for MIR4749 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4749 Gene

No ASD Table

Relevant External Links for MIR4749 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR4749 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4749 Gene:

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4749 Gene

Orthologs for MIR4749 Gene

Evolution for MIR4749 Gene

Gene Tree for MIR4749 (if available)
Gene Tree for MIR4749 (if available)

No data available for Orthologs for MIR4749 Gene

Paralogs for MIR4749 Gene

No data available for Paralogs for MIR4749 Gene

Variants for MIR4749 Gene

Sequence variations from dbSNP and Humsavar for MIR4749 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10423897 -- 49,853,932(+) GGAGC(C/T)TTAGG intron-variant, upstream-variant-2KB
rs112926952 -- 49,853,017(+) CTGAC(G/T)ACTGC intron-variant, upstream-variant-2KB
rs113897016 -- 49,854,830(+) CCATA(G/T)GGAGA downstream-variant-500B, splice-acceptor-variant
rs115035661 -- 49,852,703(+) CTGCT(C/G)TCCTA intron-variant, upstream-variant-2KB
rs11558837 -- 49,854,668(+) CTACT(C/T)TGACT nc-transcript-variant, downstream-variant-500B, reference, missense, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR4749 Gene

Variant ID Type Subtype PubMed ID
dgv53n68 CNV loss 17160897
dgv54n68 CNV loss 17160897
nsv1140251 OTHER inversion 24896259
nsv470150 CNV gain 18288195
nsv524068 CNV loss 19592680
nsv524534 CNV loss 19592680
nsv526372 CNV loss 19592680
nsv953600 CNV deletion 24416366
nsv9739 CNV gain+loss 18304495

Relevant External Links for MIR4749 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4749 Gene

Disorders for MIR4749 Gene

Relevant External Links for MIR4749

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR4749 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4749 Gene

Publications for MIR4749 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4749 Gene

Sources for MIR4749 Gene

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