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Aliases for MIR4748 Gene

Subcategory (RNA class) for MIR4748 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4748 Gene

  • MicroRNA 4748 2 3 5
  • Hsa-Mir-4748 3
  • Mir-4748 3

External Ids for MIR4748 Gene

Previous GeneCards Identifiers for MIR4748 Gene

  • GC19U901539
  • GC19P010892

Summaries for MIR4748 Gene

Entrez Gene Summary for MIR4748 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4748 Gene

MIR4748 (MicroRNA 4748) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4748 Gene

Genomics for MIR4748 Gene

Regulatory Elements for MIR4748 Gene

Enhancers for MIR4748 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F010783 1 Ensembl ENCODE 0.8 +4.1 4099 0.9 KLF1 MAX ZIC2 ZNF121 OSR2 SCRT2 ZNF341 PRDM10 WT1 SMARCA4 SLC44A2 GC19P010786 MIR4748
GH19F010776 0.5 Ensembl ENCODE 0.8 -3.1 -3090 1.4 ZIC2 ZNF101 ZNF335 ZNF664 GLIS2 POLR2A PATZ1 ZNF433 ZNF202 ZNF639 ZNF627 YIPF2 TIMM29 FBXL12 MIR199A1 RAVER1 KRI1 SLC44A2 CDKN2D MIR1181
GH19F010779 1 Ensembl ENCODE 0.8 +0.2 233 2.0 JUN KLF17 ZIC2 ZNF121 HIC1 POLR2A SCRT2 ZNF600 EGR2 SCRT1 MIR199A1 SLC44A2 SMARCA4 ILF3-AS1 MIR4748 GC19P010786
GH19F010768 1.2 Ensembl ENCODE 0.4 -10.6 -10566 2.3 HDGF ARNT MLX CREB3L1 ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF143 KANK2 DOCK6 LOC105372273 UBE2L4 S1PR2 FBXL12 CNN1 CDKN2D KRI1 ZNF627
GH19F010746 1.4 FANTOM5 Ensembl ENCODE 0.3 -23.0 -23041 20.8 MLX DMAP1 YY1 SLC30A9 ZNF143 ZNF263 MCM3 SP3 NFYC TBX21 FBXL12 HNRNPA1P10 SLC44A2 CDKN2D ZNF627 RAVER1 DNM2 KRI1 MIR638 PRKCSH
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR4748 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4748 Gene

Chromosome:
19
Start:
10,780,254 bp from pter
End:
10,780,335 bp from pter
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR4748 Gene

Genes around MIR4748 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4748 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4748 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4748 Gene

Proteins for MIR4748 Gene

Post-translational modifications for MIR4748 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4748 Gene

Domains & Families for MIR4748 Gene

Gene Families for MIR4748 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4748: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4748 Gene

Function for MIR4748 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4748 Gene

Localization for MIR4748 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4748 Gene

Pathways & Interactions for MIR4748 Gene

SuperPathways for MIR4748 Gene

No Data Available

Interacting Proteins for MIR4748 Gene

Gene Ontology (GO) - Biological Process for MIR4748 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4748 Gene

Transcripts for MIR4748 Gene

mRNA/cDNA for MIR4748 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4748 Gene

No ASD Table

Relevant External Links for MIR4748 Gene

GeneLoc Exon Structure for
MIR4748
ECgene alternative splicing isoforms for
MIR4748

Expression for MIR4748 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR4748 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4748 Gene:

MIR4748
genes like me logo Genes that share expression patterns with MIR4748: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR4748 Gene

Orthologs for MIR4748 Gene

Evolution for MIR4748 Gene

ENSEMBL:
Gene Tree for MIR4748 (if available)
TreeFam:
Gene Tree for MIR4748 (if available)

No data available for Orthologs for MIR4748 Gene

Paralogs for MIR4748 Gene

No data available for Paralogs for MIR4748 Gene

Variants for MIR4748 Gene

Sequence variations from dbSNP and Humsavar for MIR4748 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10419721 -- 10,779,838(+) tagta(A/G)agatg intron-variant, upstream-variant-2KB
rs10420961 -- 10,779,163(+) CGAGC(C/T)GAGAT intron-variant, upstream-variant-2KB
rs113852710 -- 10,780,636(+) CTTTA(C/T)GGGAA intron-variant, downstream-variant-500B
rs117743749 -- 10,780,339(+) CACCC(C/G)GACCC intron-variant, downstream-variant-500B
rs12462887 -- 10,779,506(+) tcttt(C/T)ttttt intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR4748 Gene

Variant ID Type Subtype PubMed ID
nsv1160584 CNV deletion 26073780
nsv833746 CNV loss 17160897
nsv833748 CNV loss 17160897

Relevant External Links for MIR4748 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4748

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4748 Gene

Disorders for MIR4748 Gene

Relevant External Links for MIR4748

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4748

No disorders were found for MIR4748 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4748 Gene

Publications for MIR4748 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4748 Gene

Sources for MIR4748 Gene

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