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Aliases for MIR4748 Gene

Subcategory (RNA class) for MIR4748 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4748 Gene

  • MicroRNA 4748 2 3 5
  • Hsa-Mir-4748 3
  • Mir-4748 3

External Ids for MIR4748 Gene

Previous GeneCards Identifiers for MIR4748 Gene

  • GC19U901539
  • GC19P010892

Summaries for MIR4748 Gene

Entrez Gene Summary for MIR4748 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4748 Gene

MIR4748 (MicroRNA 4748) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR4748 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4748 Gene

Genomics for MIR4748 Gene

Regulatory Elements for MIR4748 Gene

Enhancers for MIR4748 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19H010776 1.2 Ensembl ENCODE dbSUPER 0.7 -3.1 -3090 1.4 ZBTB21 ZNF664 ZNF433 ZNF639 ZNF202 ZNF680 ZNF654 NR2F1 OVOL3 ZNF404 KRI1 ZNF627 ILF3 DNMT1 YIPF2 TIMM29 PPAN FBXL12 MIR199A1 ZNF846
GH19H010779 1 Ensembl ENCODE dbSUPER 0.7 +0.2 233 2 ZNF362 JUND JUN MIR199A1 SLC44A2 SMARCA4 ILF3-AS1 MIR4748 GC19P010786
GH19H010757 1.6 Ensembl ENCODE dbSUPER 0.4 -17.5 -17546 9.8 HDGF PKNOX1 FOXA2 MLX SIN3A ARID4B DMAP1 YY1 SLC30A9 ZNF207 MIR199A1 SLC44A2 DNM2 MIR638 KRI1 CDKN2D SMARCA4 MIR4748 PIR47140
GH19H010783 0.9 Ensembl ENCODE dbSUPER 0.7 +4.1 4099 0.9 POLR2A MAX SMARCA4 SLC44A2 MIR4748 GC19P010786
GH19H010746 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -30.0 -30049 6.8 HDGF FOXA2 MLX ARNT ARID4B SIN3A DMAP1 ZNF2 ZNF766 FOS SLC44A2 CDKN2D ILF3-AS1 ICAM3 DNM2 KRI1 HNRNPA1P10 TYK2 ICAM1 C19orf38
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4748 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR4748 Gene

Genomic Locations for MIR4748 Gene
chr19:10,780,254-10,780,335
(GRCh38/hg38)
Size:
82 bases
Orientation:
Plus strand
chr19:10,890,930-10,891,011
(GRCh37/hg19)

Genomic View for MIR4748 Gene

Genes around MIR4748 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4748 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4748 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4748 Gene

Proteins for MIR4748 Gene

Post-translational modifications for MIR4748 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4748 Gene

Domains & Families for MIR4748 Gene

Gene Families for MIR4748 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4748: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4748 Gene

Function for MIR4748 Gene

Phenotypes From GWAS Catalog for MIR4748 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4748 Gene

Localization for MIR4748 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR4748 Gene

Pathways & Interactions for MIR4748 Gene

SuperPathways for MIR4748 Gene

No Data Available

Interacting Proteins for MIR4748 Gene

Gene Ontology (GO) - Biological Process for MIR4748 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4748 Gene

Drugs & Compounds for MIR4748 Gene

No Compound Related Data Available

Transcripts for MIR4748 Gene

mRNA/cDNA for MIR4748 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4748 Gene

No ASD Table

Relevant External Links for MIR4748 Gene

GeneLoc Exon Structure for
MIR4748
ECgene alternative splicing isoforms for
MIR4748

Expression for MIR4748 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4748 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4748 Gene:

MIR4748
genes like me logo Genes that share expression patterns with MIR4748: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4748 Gene

Orthologs for MIR4748 Gene

Evolution for MIR4748 Gene

ENSEMBL:
Gene Tree for MIR4748 (if available)
TreeFam:
Gene Tree for MIR4748 (if available)

No data available for Orthologs for MIR4748 Gene

Paralogs for MIR4748 Gene

No data available for Paralogs for MIR4748 Gene

Variants for MIR4748 Gene

Sequence variations from dbSNP and Humsavar for MIR4748 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000396972 -- 10,779,657(+) CATGT(A/G)CGATT intron-variant, upstream-variant-2KB
rs1000840101 -- 10,779,179(+) CACTT(C/T)ACTCC intron-variant, upstream-variant-2KB
rs1000869616 -- 10,778,944(+) GGCAT(A/G)GTGAC intron-variant, upstream-variant-2KB
rs1001568708 -- 10,779,258(+) TTTAT(C/T)GGAGC intron-variant, upstream-variant-2KB
rs1001928380 -- 10,780,392(+) GGGCC(G/T)TTGGG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4748 Gene

Variant ID Type Subtype PubMed ID
nsv833748 CNV loss 17160897
nsv833746 CNV loss 17160897
nsv1160584 CNV deletion 26073780

Relevant External Links for MIR4748 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4748

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4748 Gene

Disorders for MIR4748 Gene

Relevant External Links for MIR4748

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4748

No disorders were found for MIR4748 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4748 Gene

Publications for MIR4748 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR4748 Gene

Sources for MIR4748 Gene

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