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Aliases for MIR4745 Gene

Subcategory (RNA class) for MIR4745 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR4745 Gene

  • MicroRNA 4745 2 3
  • Hsa-Mir-4745 3

External Ids for MIR4745 Gene

Previous GeneCards Identifiers for MIR4745 Gene

  • GC19U901548
  • GC19P000809
  • GC19P000815

Summaries for MIR4745 Gene

Entrez Gene Summary for MIR4745 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4745 Gene

MIR4745 (MicroRNA 4745) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4745 Gene

Genomics for MIR4745 Gene

Genomic Location for MIR4745 Gene

Start:
804,940 bp from pter
End:
805,001 bp from pter
Size:
62 bases
Orientation:
Plus strand

Genomic View for MIR4745 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR4745 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4745 Gene

No data available for Regulatory Elements for MIR4745 Gene

Proteins for MIR4745 Gene

Post-translational modifications for MIR4745 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4745 Gene

Domains for MIR4745 Gene

Gene Families for MIR4745 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4745: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4745 Gene

Function for MIR4745 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR4745 Gene

Localization for MIR4745 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4745 Gene

Pathways for MIR4745 Gene

SuperPathways for MIR4745 Gene

No Data Available

Interacting Proteins for MIR4745 Gene

Gene Ontology (GO) - Biological Process for MIR4745 Gene

None

No data available for Pathways by source for MIR4745 Gene

Transcripts for MIR4745 Gene

mRNA/cDNA for MIR4745 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4745 Gene

No ASD Table

Relevant External Links for MIR4745 Gene

GeneLoc Exon Structure for
MIR4745
ECgene alternative splicing isoforms for
MIR4745

Expression for MIR4745 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR4745 Gene

Orthologs for MIR4745 Gene

Evolution for MIR4745 Gene

ENSEMBL:
Gene Tree for MIR4745 (if available)
TreeFam:
Gene Tree for MIR4745 (if available)

No data available for Orthologs for MIR4745 Gene

Paralogs for MIR4745 Gene

No data available for Paralogs for MIR4745 Gene

Variants for MIR4745 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR4745 Gene

Variant ID Type Subtype PubMed ID
nsv910109 CNV Loss 21882294
nsv470101 CNV Loss 18288195
dgv3508n71 CNV Loss 21882294
dgv3513n71 CNV Loss 21882294
dgv3516n71 CNV Loss 21882294
nsv910224 CNV Loss 21882294
nsv910260 CNV Loss 21882294
dgv3544n71 CNV Gain 21882294
nsv910269 CNV Gain+Loss 21882294
dgv3546n71 CNV Loss 21882294
dgv3547n71 CNV Loss 21882294
dgv3548n71 CNV Loss 21882294
dgv3549n71 CNV Loss 21882294
dgv3550n71 CNV Loss 21882294
nsv828353 CNV Loss 20364138
dgv3551n71 CNV Loss 21882294
dgv3552n71 CNV Loss 21882294
nsv910292 CNV Loss 21882294
dgv3553n71 CNV Loss 21882294
dgv3554n71 CNV Loss 21882294
nsv910310 CNV Loss 21882294
dgv3555n71 CNV Loss 21882294
nsv828354 CNV Gain 20364138
nsv458321 CNV Loss 19166990
dgv3556n71 CNV Loss 21882294
dgv3557n71 CNV Loss 21882294

Relevant External Links for MIR4745 Gene

HapMap Linkage Disequilibrium report
MIR4745

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR4745 Gene

Disorders for MIR4745 Gene

No disorders were found for MIR4745 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR4745 Gene

Publications for MIR4745 Gene

  1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

Products for MIR4745 Gene

Sources for MIR4745 Gene

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