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Aliases for MIR4744 Gene

Subcategory (RNA class) for MIR4744 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR4744 Gene

  • MicroRNA 4744 2 3 5
  • Hsa-Mir-4744 3

External Ids for MIR4744 Gene

Previous GeneCards Identifiers for MIR4744 Gene

  • GC18U900670
  • GC18M046581

Summaries for MIR4744 Gene

Entrez Gene Summary for MIR4744 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR4744 Gene

MIR4744 (MicroRNA 4744) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR4744 Gene

Genomics for MIR4744 Gene

Regulatory Elements for MIR4744 Gene

Enhancers for MIR4744 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18G049050 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -2.7 -2746 3.2 ZNF263 SIN3A MAX REST HIC1 FOSL1 JUND PRDM10 FOS EGR2 SMAD7 DYM MIR4744 ENSG00000265128
GH18G049044 1 ENCODE dbSUPER 0.7 +4.3 4290 1.5 ZSCAN26 ZNF473 ZSCAN4 ZNF195 SALL2 ZIC2 TCF12 ZFHX2 ZNF776 ZNF791 RPL17 SMAD7 CTIF MIR4744 LOC100129878
GH18G049054 1.7 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -6.2 -6161 2.6 FOXA2 ZNF766 FOS RELB IKZF2 CREM USF2 GATAD2B ZNF592 RAD51 DYM SMAD7 MIR4744 ENSG00000265128
GH18G049047 0.7 ENCODE dbSUPER 0.7 +1.5 1508 1.3 CTCF TEAD4 JUNB SMAD7 MIR4744 LOC100129878
GH18G049061 1.2 Ensembl ENCODE dbSUPER 0.4 -12.3 -12264 1.5 PKNOX1 TAL1 ZNF175 FOSL1 TCF12 NCOR1 SMARCE1 L3MBTL2 RNF2 DPF2 MIR4744 ENSG00000265128
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR4744 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR4744 Gene

Chromosome:
18
Start:
49,049,687 bp from pter
End:
49,049,768 bp from pter
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR4744 Gene

Genes around MIR4744 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR4744 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR4744 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR4744 Gene

ORGUL Member Location for MIR4744 Gene

ORGUL Member Location for MIR4744 gene

Proteins for MIR4744 Gene

Post-translational modifications for MIR4744 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR4744 Gene

Domains & Families for MIR4744 Gene

Gene Families for MIR4744 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR4744: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR4744 Gene

Function for MIR4744 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR4744 Gene

Localization for MIR4744 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR4744 Gene

Pathways & Interactions for MIR4744 Gene

SuperPathways for MIR4744 Gene

No Data Available

Interacting Proteins for MIR4744 Gene

Gene Ontology (GO) - Biological Process for MIR4744 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR4744 Gene

Drugs & Compounds for MIR4744 Gene

No Compound Related Data Available

Transcripts for MIR4744 Gene

mRNA/cDNA for MIR4744 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR4744 Gene

No ASD Table

Relevant External Links for MIR4744 Gene

GeneLoc Exon Structure for
MIR4744
ECgene alternative splicing isoforms for
MIR4744

Expression for MIR4744 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR4744 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR4744 Gene:

MIR4744
genes like me logo Genes that share expression patterns with MIR4744: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR4744 Gene

Orthologs for MIR4744 Gene

Evolution for MIR4744 Gene

ENSEMBL:
Gene Tree for MIR4744 (if available)
TreeFam:
Gene Tree for MIR4744 (if available)

No data available for Orthologs for MIR4744 Gene

Paralogs for MIR4744 Gene

No data available for Paralogs for MIR4744 Gene

Variants for MIR4744 Gene

Sequence variations from dbSNP and Humsavar for MIR4744 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs1002033799 -- 49,051,089(+) CAGGC(C/T)TTTCC intron-variant, upstream-variant-2KB
rs1003141322 -- 49,050,319(+) CTCCC(A/G)ACCTC intron-variant, upstream-variant-2KB
rs1004588586 -- 49,049,260(+) GAAAC(A/T)ACTAC intron-variant, downstream-variant-500B
rs1005961103 -- 49,049,723(+) ATGTT(G/T)ACTAT intron-variant, nc-transcript-variant
rs1005993748 -- 49,049,334(+) ACTCA(A/G)TAAAT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR4744 Gene

Variant ID Type Subtype PubMed ID
nsv1055175 CNV gain 25217958
nsv833646 CNV gain 17160897

Relevant External Links for MIR4744 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR4744

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR4744 Gene

Disorders for MIR4744 Gene

Relevant External Links for MIR4744

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR4744

No disorders were found for MIR4744 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR4744 Gene

Publications for MIR4744 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR4744 Gene

Sources for MIR4744 Gene

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